NPR

Taking Shortcuts In Drug Testing Can Put Patients At Risk

Researchers use intermediate endpoints like how a drug lowers cholesterol to get a quick sense of whether the drug might improve health. But those shortcuts often don't show true benefits and harms.
Source: Jamel Akib

We all want breakthroughs in medicine. I've never met someone who doesn't.

Even with all the progress we have seen in medicine, millions of people suffer, or have family members who suffer, from diseases that are making their lives worse or threatening their lives. Time means something different to these people. They do not have the luxury of waiting patiently while researchers test new drugs.

There is growing interest in reducing the evidence required to approve new drugs and to more rapidly deliver new therapies to patients. The sentiment behind speeding approval is a good one – no one wants to delay the availability

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