The Atlantic

When Missed Periods Are a Metabolic Problem

The hormonal disorder known as Polycystic Ovary Syndrome affects around 10 percent of women, but scientists are only just beginning to understand it.
Source: ET1972 / Shutterstock

When the former NFL cheerleader Natalie Nirchi stopped menstruating at age 17, she was diagnosed with polycystic ovary syndrome (PCOS), a hormone disorder affecting up to 10 percent of women of reproductive age. She didn’t initially show any of the physical symptoms, like excess hair growth, cystic acne, or obesity, but a blood test revealed that she had high levels of testosterone and an ultrasound showed cysts on her ovaries.

“My doctor mentioned that one day I might have trouble getting pregnant, but didn’t offer any other information about the disorder,” Nirichi said. Other than the absence of her period, PCOS did not significantly impact her life until college, when she began experiencing shooting pains in her pelvis, mood swings, and rapid weight gain despite a rigorous exercise routine.

“It wasn’t like I turned 21 and started partying, it was like I turned 21 and all of a sudden, I was extremely depressed. No matter what I did, I just kept building this layer of extra weight around my midsection,” she said.

PCOS is genetic and presents differently in each woman of of the 728 women in the cohort had PCOS, but had no pre-existing diagnosis.  

You’re reading a preview, subscribe to read more.

More from The Atlantic

The Atlantic5 min readSocial History
The Pro-life Movement’s Not-So-Secret Plan for Trump
Sign up for The Decision, a newsletter featuring our 2024 election coverage. Donald Trump has made no secret of the fact that he regards his party’s position on reproductive rights as a political liability. He blamed the “abortion issue” for his part
The Atlantic6 min read
The Happy Way to Drop Your Grievances
Want to stay current with Arthur’s writing? Sign up to get an email every time a new column comes out. In 15th-century Germany, there was an expression for a chronic complainer: Greiner, Zanner, which can be translated as “whiner-grumbler.” It was no
The Atlantic5 min readAmerican Government
What Nikki Haley Is Trying to Prove
This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here. Nikki Haley faces terrible odds in her home state of

Related Books & Audiobooks