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    Understanding DNA: The Molecule and How It Works
    Understanding DNA: The Molecule and How It Works
    Understanding DNA: The Molecule and How It Works
    Ebook342 pages7 hours

    Understanding DNA: The Molecule and How It Works

    By Chris R. Calladine and Horace Drew

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    About this ebook

    The Second Edition of Understanding DNA has been entirely revised and updated, and expanded by more than 50% to cover new advances. The book explains step-by-step how DNA forms specific structures, the nature of these structures, and how they fundamentally affect the biological processes of transcription and replication.The functional properties of any molecule are directly related to and affected by its structure; this is especially true for DNA, the molecule that carries the code for all life on earth. Written in a clear, concise, and at times lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry, and genetics students, for newcomers to the field from such areas as physics or chemistry, and for even the most seasoned researchers who really want to understand DNA.

    Key Features* New edition, expanded by more than 50%* Completely revised and updated* Includes many additional and updated references* Summarizes the recent studies of DNA in disease and medicine* Contains more than 110 illustrations, some in full color* Describes the basic units of DNA and how these form the double helix* Characterizes the various types of DNA double helix that have been found* Explains how and why DNA twists and curves* Discusses the mechanisms of DNA supercoiling* Summarizes the assembly of DNA and proteins into chromosomes* Outlines the methods used to study DNA structureDescribes the latest work on protein-DNA complexes* Contains simple exercises and further reading at the end of each chapter
    LanguageEnglish
    PublisherAcademic Press
    Release dateMar 14, 1997
    ISBN9780080572529
    Understanding DNA: The Molecule and How It Works
    Author

    Chris R. Calladine

    Chris Calladine is Professor of Structural Mechanics at the University of Cambridge. In addition to researching aspects of structural engineering, he has applied the methods of structural mechanics to the study of flagella and DNA.

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    • 3/5
      A book that is very definitely biochemistry rather than molecular biology. None of that stuff about genes, expression, operons and so on. This was about the physical properties of the DNA molecule: how and why it curls, what methylation is chemically, things like that. Obviously the details of this stuff don't much matter to me, and there were some parts that were a hard slog and that I skipped over. But, all in all, it was an interesting and worthwhile read; not too hard to understand, and very interesting to see a different side of DNA science.

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