IBUPROFEN

1. Name & class of drug – generic and trade name.

GENERIC NAME: Ibuprofen

BRAND NAME: Actiprofen, Advil, Motrin, Cramp end, Excedrin IB, Genpril, Haltran, Ibuprin, Midol, Pamprin-IB, Nuprin
CLASSIFICATION: Nonsteiroidal anti-inflammatory, antipyretic

2. Dose range and routes for adult & geriatric client.

PREPARATIONS: PO

DOSING: Analgesia Adult (PO) 200 - 400 mg q 4-6h, (not to exceed 3.2 g/24h)
Antiinflammatory (PO) 300 - 800 mg tid – qid, (not to exceed 3.2g/24h)

3. Purpose prescribed. Underline reason your client is prescribed drug.

USES: Rheumatoid arthritis, osteoarthritis, primary dysmenorrheal, gout, dental pain, musculoskeletal disorders, fever

4. Major side effects & drug interactions.

DRUG INTERACTIONS: decreased effect of antihypertensives, thiazides, furosemide

• Decreased ibuprofen action, aspirin
• Increased risk of bleeding: cefamandole, cefotetan, cefoparazone, valproic acid, thrombolytics, antiplatelets, warfarin
• Increased possibility of blood discrasias: antineoplastics, radiation
• Increased toxicity: digoxin, lithium, oral anticoagulants, cyclosporine, probenecid
• Increased GI reactions: aspirin, corticosteiroids, NSAIDs, alcohol
• Increased hypoglycemia: oral antidiabetics, insulin

SIDE EFFECTS: headache, nausea, anorexia,

5. Nursing Implications & teaching.

• Report blurred vision, ringing, roaring in ears; may indicate toxicity; eye and hearing tests should be done during long-
term therapy
• Avoid driving, other hazardous activities if drowsiness or dizziness occurs.
• Report change in urinary pattern, increased weight, edema, increased pain in joints, fever, blood in urine, indicate
nephrotoxicity.
• Therapeutic inflammatory effects may take up to 1 mo.
• Avoid alcohol, NSAIDs, salicylates; bleeding may occur
• Use sunscreen to prevent photosensitivity.