Journal of Dental Hygiene Science Vol. 2, No. 1, pp.

0~0 (2002)

 
         

 
1

 
 

Effect of Gargle Containing Citrex and Cetylpyridinium Chloride on the Oral Pathogenic Bacteria
Young-Min Park and Eun-Suk Lee
Department of Dental Hygiene, Yeojoo Institute of Technology(YIT) Kyo-ri 454-5, Yeojoo-up, Yeojoo-gun, Kyonggi-do 880-705, Korea 1 Department of Dental Hygiene, Kimcheon College, Kimcheon, Gyeonbuk 740-704, Korea


 The purpose of this study was to investigate that the effect of Citrex and CPC on the growth of oral microorganism such as Streptococcus mutans KCTC 3065, Candida albicans KCTC 7122, and Staphylococcus aureus KCTC 1916 which were cariogenic, candidiasis(bleeding gum, dry mouth and tongue, thrush) and angular cheilitis inducing bacteria, respectively. The efficacy of complex of Citrex and CPC was determined in assays measuring Halo Test. The gargle containing Citrex(0.02%) and CPC(0.02%) demonstrated broad-spectrum anti-microbial properties, with activity against both Gram-positive and Gram-negative and a yeast(Candida albicans).   
CPC, Citrex, Streptococcus mutans, Candida albicans, Staphylococcus aureus

  
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Corresponding author Tel: Fax: E-mail:

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Effect of Gargle Containing Citrex and Cetylpyridinium Chloride on the Oral Pathogenic Bacteria

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1* x => p q& Candida albicans KCTC 1916 ? BHI(Brain heart infusion), MHM(Mueher hinton medium) MHM ee > +u  x MN +1. 2. ee p q< 2.010 cfu/ml# 5 /^ e petri dish 1 ml  +u  _, paper disk(Whatman, USA) e petri dish 3s O 1. 3 ! "< 1/25 +u 1 paper disk 100 l<, 2 disk. 3 !" "< 50 l u+, z, 3 paper disk. 3 !" " 100 l ee  +1. . 1 2 paper disk Tap Water 100 l z, 3 paper disk. * 100 l < ['+1. 5.  (M-PHP ) 5I  ( L$ _ 30  M-PHP5 6 !#  Q< d5 1) $ +d, I d5 !" 15 ml 1  , !_ 2) $
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5

Journal of Dental Hygiene Science Vol. 2, No. 1, pp. 0~0 (2002)

3+1.

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mutans

Citrex  CPC    Streptococcus    .



 
 $ % x -& '
 18.58087 ( ) 9.62501 #* 14.77805 + , 14.41495 -. 9.16392 / 0 2.244805
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P-value 0.00095* 0.02204*** 0.00518** 0.00239** 0.2719NS 0.52318

aureus

 

Citrex  CPC       .

Staphyloccuc

*; P<0.001, **; P<0.01, ***; P<0.005, NS; Not significant statically

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 CPC    Candida albicans 

Effect of Gargle Containing Citrex and Cetylpyridinium Chloride on the Oral Pathogenic Bacteria


  
 !"#$      t-value P-value  ! 2.01 0.050 " ! 1.42 0.165 # ! 0.73 0.470 $ ! 0.89 0.377 %& ! 0.14 0.890

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   .  !" 36: 734-737, 1998. 2. #$ , %&, '(, )*, +,-, ./: Grapefruit 0
1 234  56 7+8, 9:;<!" 23(5): 1991. 3. =, >?>, -@, )(, #$ : Grapefruit 0
123 Enterbacter pyrinus AB
C DE ,F. 9:;<!" 27(6): 614-618, 1995. 4. >G , HI<, JKL, M', )0H, NO,:
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123 Q 123 R UDCA HS TUVW S. mutansX  6 Y8 R Z[\]8 ^ _. `ab<!" 22(1): 37-46, 1998. 5. `c., )de, f=g, )0@: h[ []GijBkl (cetylpyridinium Chloride) HS mW Z[ n DE , F ^ o- pq_. `ab<!" 19:35, 1995. 6. rs, )t, uL, f/v: wQ 12 xy z{ 123   8 ^ _. `ab<!" 15: 377-389, 1991. 7. ur>, N, |}~, #+
, +, f=g, ':
P, c
R   S. mutans :n8. `ab <!" 19: 357, 1995.
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8. Silness J, Loe, H: Periodental disease in pregnancy, II. Correlation between oral hygiene and periodontal condition. Acta Prevalence and Severity 22: 533-551, 1963. 9. Loe H and Silness J: Periodontal disease in pregnancy. 1. Prevalence and severity. Acta Odont Scand 21: 533-551, 1963. 10. Splosky VW, Bhatia HL, Forsythe A, Levin D: The Effect of antimicrobial mouth awsh on dental plaque and gingivitis in young adults. J periodontol 46: 685, 1975. (Received May 9, 2002; Accepted June 17, 2002)