Comparison between Innate and Adaptive Immunity

Primary cells Origin of cells Site of Location of Primary Primary actions Allergic
maturation mature cell secretory Reaction
product
Innate Immunity

Neutrophils, Red bone marrow Red bone Blood, connective Histamin, Inflamatory None
eosinophils, marrow(Neutroph tissue and complement, response and
basophils, mast ils, eosinophils, lymphatic tissue prostaglandin, phagocytosis
cells, monocytes basophils and leukotrienes,
and macrophages monocytes) and kinins and
tissues (mast cell interferons
and macrophages)

Adaptive
immunity

Antibody- Red bone marrow Red bone marrow Blood and Antibodies Protection against Immediate
mediated lymphatic tissue extracellular hypersensitivity
immunity antigens
B cells

Cell-mediated Red bone marrow Thymus Blood and Cytokines Protection against Delay
immunity lymphatic tissue intracellular hypersensitivity
T cells antigens( viruses
and intracellular
bacteria) and
tumors;
responsible for
graft rejection