Lecture 1- Mitosis & Meiosis

Mitosis
a specific phase of normal cell division.

Meiosis
generation of sex cells, sperm & ovum. 1/2 the number of chromosomes.

Mitosis
cells reproduce by duplicating their contents and dividing in two.
u nicellular organisms (bacteria, yeast) each cell division produces a new organism. multicellular organisms require many rounds of cell division. required in adult to replace cells lost through wear & tear or programmed cell death.
adult humans many millions of cells each second.

Mitosis
produce a pair of genetically identical daughter cells.
DNA replicated chromosomes segregated into each cell cytoplasm and organelles must replicate and divide.

Controlled by proteins conserved from yeast to humans.

cyclins

Interphase

Interphase

Early Prophase

Interphase

Early Prophase

Late Prophase

Interphase

Early Prophase

Late Prophase

Prometaphase

Metaphase

Metaphase

Early Anaphase

Metaphase

Early Anaphase

Late Anaphase

Metaphase

Early Anaphase

Late Anaphase

Late Telephase

Prophase

Prometaphase

Metap h a s e

Anaphase

Telep h a s e

Kinetochore

Microtubule Spindle

Cytokinesis

Meiosis

Meiosis