Iron deficiency Symptoms Fatigue tachycardia palpiatatons dyspnea on exertion PICA (CRAVINGS) Low <12 mcg/L Elevated High

Increased Decreased

Chronic Thalassemia Vit B12 disease deficiency (inflammation) Symptoms of Diarrhea chronic anorexia condition NEUROLOGIC SYNDROME!!

Autoimmune hemolytic Sickle cell anemia Fatigue Acute pain Angina/CHF Fever Jaundice/splenomegaly anemia

Serum Iron Ferritin Transferrin TIBC Platelet MCV

Low Elevated Elevated Low Normal or slightly reduced Not <60%

Normal High Increased Low? Low Elevated (110140 fL) Low High? Elevated Macroovalocytes Reticulocytosis Hypersegmented Spherocytes neutrophils Erythrocyte anisocytosis agglutinationwith cold poikilocytosis agglutinin disease High Normocytic Normochromatic Sickle cells Reticulocytosis Hyposplenism via Howell-Jolly bodies Increased usually 20-30% Micro/hypo Targeting

Hct RDW Elevated Reticulocyte Blood Anisocytosis smear (cell size) poikilocytosis (cell shape) hypochromic microcytic cigar shaped/pencil

Normal Normocytic normochromic

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