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US 2008/0292721 Al lays and 17 days following inoculation, All eatments were applied by spray uatil the surfaces of te plant leaves were fully wetted (bogan to drip). Two sets of plants were used as positive and negative controls: te frst set was treated with ‘water only (Treatment A) and not inoculated. The second set was also treated with water only, but was also inoculated ‘concurrent withthe others. The speific formulations foreach sw i Bon nie FMibapi owe 628350 mt wate’ ester [0148] Six days following the second treatment, the plants ‘were evaluated for ltermaria leat spot by visual inspection. The results ofthe leaf spot evaluation were as presented in ‘Table 21. As seen in Table 21, those plants treated with the lowest concentration of the bioactive composition (with ~5 ‘ppm of each metal ion Treatment C) stl showed nearly a 50% drop in leaf spot formation, Doubling the bioactive composition (10 ppm of each metal ion—Treatment D) reduced Jeaf spot by ever 75%. Somewhat similar results were found with the two dilutions of the commercial fungi- cide Eagle 40WP with the lower concentration (Treatment H) rexlucing leaf spot by about 30% while the higher concentra tion (Lreatment 1 reduced leaf spot by 80%. Combining the two provided marked improvement with, oddly enough, the ‘combination of the two lowest concentrations providing nearly comple inhibition of lea spot manifestation, The ‘other commercial Fuangicide Seala SC provided no inhibition ‘and, appeared to promote the manifestation of lat spot. TABLE 21 Fo 8o bow oo s 3 © 08 5 0 0s wo at hoo 8 8308 9 ey toe D0 SD 33 [0149] Fleven days following the ast treatment, disease overly was once again astessed. However, owing to the numberof spots which made giving @ mamercal assessment impossible, disease severity was recorded using the following scale: I-1—nodisease, 2~ slight, 3~moderae, 4severeto ‘5 plant dead. The results are presented in Table 22. Noy. 27, 2008 TABLE 22 [0180] As shown in Table 22, the bioactive compositions cording to the presen invention provided excellntprotee= ‘ion agains leaf spot, with those plants treated at the higher level and in combination with the commercial fungicide ale 40WP showing nearly the same level of disease asthose thathad not been inoculated at all. On the contrary, the Eagle alone, even atthe recommended application rate, proved less ‘efficacious than the bioactive eomposition, Finally, the Seala ‘nce again failed to show any efficacy and, in fact, proved ‘ore detrimental. It was suspected that the Scala treted plants nunifested both lea spot disease and phytotoxicty ‘None ofthe plants treated with the bioactive composition or the commercial Eagle fungicide showed evidence of phyto- tonicity, EXAMPL 1 Fire Blight on Crabapples [0151] _ study ofthe bioeticaey of the various agrichemi- cal compositions, including bioactive acid solutions. and beads thereof with an antibiotic agrichemical, were eval= ated to assess their bioelficacy against fie blight on era- ‘apple. The stidy was conducted on year old Snow Drift crabapple trees, with cach othe compositions being applied to ten tees in two-subplotsof fie trees, four different ime at 100% bloom-—day I, a second application was made on day 4, third on day 11 anda final treatment on day 19. The ‘woes were inoculated with F, amlovora ISBN ata concen ‘cation of 410” cells per milter on day 1 following drying ofthe treatment, with the inoculation being repeated on day 13, Evaluation for fire blight was completed on 100 blossoms for each of the subplots on day 12, day 19 and day 27. Additionally, the incidence of shoot infection andthe length ‘ofcankers were evaluated on day 63. The results are shown in Table 23, [0152] The test compositions were prepared by forming solutions ofthe bioactive agents. Two diferent dilutions of the MI2 biosctive were evaluated, the fist employing 94.46 ‘il/gallon @5 mi of water (S ppm of each metal) and the second 188.9 ml/galon (60 mal) of water (10 ppm of each metal). A streptomycin product (17% concentrated) was dliluted ata rate of 0.049 Tbs/gallon ($8.72 /}) (200 ppm). nly copper le wa ited ano aca (119.8 g/), Bach ofthe compositions and blends were s lid et rat of 50 gallons (1893 1) pre are. The specie {ests and the results atained therewith are showin Table 2, The results ate presented as the mean of the counts. [0153] As seenin Table 23, all tested compositions showed ewer infected flowers as compared tothe contol. The eom- US 2008/0292721 Al bination of the MIZ acid solution with streptomyein pet formed better than either biowctive alone, A siguiieaat rate response wats soon between the two MI2 compositions: the 10 ‘ppm solution performing significantly beter than the 5 ppm Solution. Shoot blight incidence wos greatly reduced for the ‘copper hydroxide, streptomycin an streptomyeivMI2 com- bination and a modest improvement with the higher concen- trated solution of MI2. Only sirepiomyein and copper hydroxide appeared to prevent canker, while measurable can- kers were noted with all compositions containing bioactive ‘eid solution, Even s, these results show a marked benefit of the bioactive acid solutions alone or in combination with streptomycin. More importantly, it ust be noted that even at the higher concentration M2 composition, the 10 ppm of | ‘ach metal, total of 30 ppm metals, ples in comparison to the more than $0,000 ppm copper in tbe capper hydroxide solution. Inessence, each application ofthecopper hydroxide release almost 1000 g or Copper ino the environment com- ‘pared less than 2 gram or any one metal released by higher ‘concentration MI2 composition sau Hye? 227g) ee ee Scene Gime ‘copper ciate an incr, co ae tm sous provide 20 ph ‘ttt ogeter wt 394 sun Laut sonata 35% eee ens [0153] Although the present invention has been deseribed ‘with respeet to the foregoing specific embodiments and ‘examples, it should be appreciated that other embodiments utilizing the concept of the present invention are possible without departing trom the scope of the invention. The is define by the claimed elements and any ns, variations, or equivalents that fall Within the spirit and seope ofthe underlying principles, We claim: 1. A bioactive agrichemical concentrate composition com- prising an intimate, substantially homogeneous, dry mixofan ‘cid and at least one source ofa least one antimicrobial metal jon, sid acid being present in atleast 40 weight percent and a a level tht represents at Jeast a2 times molar excess, relative lo the anlmicrobjal metal ions of the source, sid bioactive composition, when said concentrate, when diluted 1o its end-use concenicaton, has a pH of less than 6 and the ‘concentration of aatimierabiel metal ion derived from the source is 500 ppm or ess, inthe eae ofa single antimicrobial ‘metal ion, or 1000 ppm or les, inthe case of multiple anti ‘mierobial metal ions Noy. 27, 2008 2. Theeoncentrateof claim I wherein the acid is present in ‘an amount of From 40 (0 $0 weight perceat 3. The concentrate of claim 1 further comprising one oF more conventioal sxlditives in concentrated amounts, sid additives selected from protective colloids, adjuvants, sabi- Tizers, binders, thickeners, thixotropie agents, penetrating agents, antifreeze agents, dofoaming agents, foaming agens, oils for spraying. corrosion inhibitors, surfactants, filers, ‘wetting agents, dispersing agents, emulsifiers, rain fasteners and dyes and other known active ingredients which have pesticide or plant growth related properties or both 4. The concentrate of claim 1 wherein the acid is presenti at least a5 times molar excess relative tothe metal ion(s) of the bioactive acid composition '. The concentrate of elaim 1 wherein the components of the bioactive acid composition are dry powders and the cote centrateis prepared by dry blending the powders. 6. The concentrate of elaias 1 wherein the biowctve acid ‘composition i prepared by forming homogeneous soliton fof the acid and metal ion source in a volatile solvent and ‘evaporating the solvent to leave # dry cake which is then ground before combining with the conventional bioactive eal active. 7. The concentrate claim 1 wherein the metal ion source is ‘one or more materials tat in the presence of wate, ets as a source of antimierobial metal ions. ‘8 The concentrate of claim 1 wherein the meta ion(s) are selected from the group consisting of silver, copper, zine, ‘mercury, tn, ron, gold, ead, bismuth, cadmium, chromium, and thallium ions and combinations of any two oF mote of seh ions 9. The concentrate of claim 1 svherein the antimirobial ‘etal jons are selected from the group consisting of silver ions, copper ions, zine ions, a combination of silver and copper ions, a combination of silver and zine ions, #combi- ‘aon of copper and zine ious and a combination of silver, ‘copper and zie ions 10, The concentrate ofelaim I wherein the acids watere soluble weak or moderate acid, 11, The conceatmte of elsim 1 wherein the aid has a pKa fat least 1 in water 12. The concentrate of ela I further comprising at east ‘one surfactant which, when the concentrate is diluted to a level where the concentration ofthe metal ion is 500 ppm ot less, enhances the bieflicacy of the composition as eom- pared to the solution without the surfctan 13, The concentrate of claim 1 wherein the pH is from 1.5 10 5 in the diluted state 14. A bioactive agrchemical active concentrate solution ‘comprising 8) an aqueous or agueous-hased concentrated acid solution, b) at least one antimicrobial metal ion or anti- ‘microbial metal ion source flly or partially dissolved in said acid solution, and e) optionally, at last one surfactant ‘wherein the concentration of the acid is at Teast shout 40 ‘weight percent acid and the acid is presenta level that is least a2 times molar excess relative To the metal ions of the acid solution, and wherein, whea the concentrate i diluted 9 its end-use composition, the pl of that composition is less than 6 and the amount of metal ion atibuted tothe acid solution is $00 ppm ores, in the case ofa single animicro- bial metal fon, oF 1000 ppm or less, in the ease of muliple Aantimierobial metal ions 15, The concentrate of claim 14 further comprising one or more conventional additives selected from protective eol- US 2008/0292721 Al Toids, adjuvants, stabilizers, binders, thickener, thixotropie ‘agenis, peneiring agents, antifreeze apents, defoaming ‘agents foaming agents, oil for spraying, corrosion ihibi- tors, surfactants, files, wetting agents, dispersing agents, ‘emulsifiers, ran fasteners, and dyes and other known ative ingrodients which have pesticide or plant growth related properties or both. 16, The concentrate of claim 14 wherein the acid solution has a concentration of from about 40 to about 80 weight PST. The concentrate of claim 14 wherein the acids present in at east a $ times molar excess relative tothe metal ion). 18, The concentrate of elim 14 whersin the metal ion(s) ‘are sleet From the group consisting of silver, copper, zinc, mercury, in, iron, gol, lead, bismuth, cadmium, eros, ‘and thallium ions and Combinations of any two or more of such ions Noy. 27, 2008 19. The concentrate of claim 14 wherein the antimicrobial ‘metal ions are selected from the group consisting of silver ions, copper ions, zine ions, a combination of silver and copper ious, a combination of silver aud zine ions, a combi- ‘ation of copper and zine ions and a combination of silver, copper and zine ions. 20. The concentrate of claim 14 wherein the acid is a water-soluble or water miscible weak or moderate acid. 21. The concentrate of claim M4 further comprising atleast ‘one surfactant which enhances the bivellicacy ofthe compo- sition a8 compared tothe safution without the surfactant 22, The concentrate of claim 14 wherein the pll of the end-use composition is from 1.50 5.