Brand name: Iterax

Generic name: Hydroxyzine

Indication: Treatment of anxiety, preoperative sedation, antiemetic, antipuritic, may be
combined with opioid anagesics
Drug classification: antianxiety agents, antihistamines, sedative
Mechanism of action: competes with histamine for H1-receptor sites on effector cells in
the GIT, blood vessels, and respiratory tract
Dosage: Adult anxiety: 25mg bid-qid or 50-100mgmg at night, premed general anesth
100-200mg the night before the surgery symptomatic treatment of pruritus and
allergic origin 30-100mg/day Children 30 mos – 15 yr 1mg/kg/day in divided
doses
Special precaution: severe hepatic dysfunction, geriatric patients, labor,
Pregnancy risk category: C
Adverse reaction: CNS: drowsiness, agitation, ataxia, dizziness, headache, weakness
Resp: wheezing GI: dry mouth, bitter taste, constipation, nausea Derm:
flushing Others: pain and abscesses at IM site, chest tightness, urinary retention
Contraindicated to: hypersensitivity, pregnancy
Form: Tablets 10mg, Capsules 10mg, syrup 10mg/5ml, oral suspension 25mg/5ml,
injection 25mg/ml
Nursing responsibilities:
 Assess client for dizziness and drowsiness
 Assess client with kidney disease
 Assess clients for allergic reactions