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Virus: A biological particle composed of nucleic acid and protein Intracellular Parasites: organism that must live inside

e a host

1) Made of cells? 2) Organization? 3) Require energy? 4) Respond to Environment? 5) Grow? 6) Reproduce? 7) Adapt?

They are not made of cells or organelles They cannot reproduce without a host They dont have both DNA and RNA They do not metabolize energy

Reproduce They have DNA or RNA They can adapt to surroundings The have organization

All Have: 1) Capsid: coat of protein that surrounds DNA or RNA 2) Nucleic Acid: RNA or DNA Some Have: Tail Fibers: Used for attachment (not legs) Shapes vary

Cannot reproduce w/o a host cell Virulent: cause disease Bacteriophages (infect bacteria) are often studied Replication is similar with many animal viruses

1st Step: Attachment


Virus lands on cell membrane Virus attaches to a cell receptor No attachment = No infection Virus acts as a key to the receptor

endocytosis

2nd Step: Entry Virus enzyme weakens cell membrane Genetic material (DNA or RNA) enters host cell

3rd Step: Replication Virus DNA/RNA uses ribosomes to make virus proteins Proteins created by transcription/translation Virus proteins make new virus parts

4th Step: Assembly (formation) New virus parts are assembled in the cytoplasm

5th Step: Lysis & Release Virus enzyme causes cell membrane to lyse New viruses are released to find new host Cycle repeats

Viral Transcription & Translation

If DNA Virus: 1) Viral DNA injected 2) Viral DNA transcribed into viral mRNA 3) Viral mRNA translated into viral proteins

If RNA Virus: 1) Viral RNA injected 2) Viral mRNA translated into viral proteins

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