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DRUG

Generic Name: Piperacillin Tazobactan Brand Name: Zosyn Classification: Anti-infective Route: IVTT Dosage: 4.5 mg now, then 2.25mg Frequency: Every 8hrs

Indications
Treatment of serious infections due to susceptible organism, including: infections, respiratory tract infection.

Mechanism of Action
Piperacillin -binds to bacterial cell wall membrane, causing cell death. Tazobactan -Inhibits betalactamase, an enzyme that can destroy penicillin. Therapeutic effect: Death of susceptible bacteria.

Contraindication
Hypersensitivity to penicillins or tazobactan. Use cautiously in: renal impairment.

Adverse reaction
CNS: Confusion, lethargy, seizure. CV: congestive heart failure, arrhythmias.

Nursing Responsibility
Do the rights of the patient.. - Right patient. - Right medication. - Right site. - Right dosage. - Right route. - Right time. - Right to refuse. Checked the patency of the IV. Inject slowly. Observed for the sign and symptoms of anaphylaxis. Provided clean environment.

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