IX.

Pathophysiology:
ETIOLOGY -Viral: adenovirus -%a "erials: S"re&"o o us &neu#oniae *ae#o&+ilus in,luen-ae RISK AND PREDISPOSING FACTORS - i!are""e s#o$in! -environ#en"al &ollu"an"s'dus"( s#o$e) -!ene"i ,a "or'Al&+a(an"i"r.&sin de,i ien .) ra e 'Cau asians) In,la##a"ion o, "+e air/a.s and lun!s

Alveoli 0e o#es ,i0rosed

release o, +e#i al #edia"ors '0rad.$inin(+is"a#ine(&ros"a!landin) in rease a&illar. &er#ea0ili".

release o, &.ro!ens ,ro# #a ro&+a!es and 1%C

ons"an" irri"a"ion In rease nu#0er o, #u us se re"in! ells '!o0le")

Overdis"en"ion o, alveoli re"en"ion o, a0on dio2ide +.&o2ia i, &rolon!ed(4 lu00in! o, nails

lun! e2&ansion ,luid3 ellular e2uda"ion +.&erven"ila"ion o, lun!s ,i2a"ion o, ri0s in ins&ira"or. &osi"ion 0arrel +es" +.&erse re"ion o, #u us &ersis"en" ou!+

De"e "ion o, +.&o"+ala#us

%ron +ial /alls "+i $ened

narro/in! o, air/a.s

de rease o2.!en de rease o2.!en d.s&nea su&&l. "o "+e 0rain su&&l. "o "+e lo/er e2"re#i"ies ene!. de&le"in! or in"er,eres ea"in! di--iness ra#&s in "+e ,ee" /ei!+" loss