Drug (brand names)

morphine immediate
release

morphine long acting

hydrocodone (Vicodin,
Lorcet, Norco, Hycet,
Lortab, Zamicet, Zydone)

hydromorphone
oxycodone (Percocet,
Oxycontin, Oxecta, Oxyfast,
Roxicodone)
oxymorphone (Opana,
Opana ER, Numorphan)
codiene (Tyl # 3, Tyl # 4)
tramadol (Ultram, Conzip,
Rybix, Ryzolt)
levorphanol (LevoDromoran)
methadone (Dolophine,
Methadose)
fentanyl (Duragesic)
meperidine (Demerol)

Brand availability
MSIR: 15,30 ($0.50)
Roxanol 2,4,20/ml ($1/ml)
supp: 5,10,20,30
Avinza:30,45,60,75,90,120
($520) Kadian:10,20,30,40,50,60,70,80,
100, 130,150,200 ($6- )
MSContin: 15,30,60,100,200 ($130/pill
for 200mg)
generic forms: 2.5/500,5/300, 5/325,
5/500, 7.5/300, 7.5/325, 7.5/500,
7.5/650, 7.5/750, 10/300, 10/325,
10/500, 10/650, 10/660,
7.5/325/15ml, 7.5/500/15ml,
10/325/15ml ($0.25 - 2)
Dilaudid: 2,4,8,1/ml ($9)
Exalgo ER: 8,12,16,32 ($19)
supp: 3
Percocet: 2.5/325, 5/325, 7.5/325,
7.5/500,10/325,10/650
Roxicodone: 5, 15, 30 ($0.5- 0.75)
Oxycontin (ER): 15, 15, 20, 30, 40, 60,
80 ($3-5)

Opana ER: 5, 7.5, 10, 15, 20, 30, 40

codeine: 15, 30, 60
Tyl
#3:300/30
Tyl
#4:300/60
Ultram: 50 Rybix ODT:50
Ultram ER (& Conzip&Ryzolt): 100,
200, 300

10 mg
SC/IM/IV

$$

30 mg po

2.5-10 mg q4-6 2-4 hours

$$$

7.5 mg po
1.5 mg
SC/IM/IV

2-8 mg q3-4

20 mg po

5-15 mg q 4-6

$$$

2.5-10 mg SC/IM/IV q 2-6

epidural 1-6 mg
(M)

(M)
NONE

NONE

1-4 mg SC/IM/IV q3-6

3 mg q6-8

NONE

NONE

(M)

200 mg po
130 mg IM

15-60 mg q4-6

120 mg po
100 mg IM

50-100 mg q 4-6

4 mg po
2 mg q 6-8
2 mg SC/IM/IV
20 mg po
10 mg IM
(variable)

(M)

(M)

12 hours

(M)
2-4 hours

200 mg max in renal

failure

24 hours
3-6 hours

2.5-10 mg
PO/SC/IM/IV q 8- 6-8 hours
12

0.1 SC/IM/IV
300 mg po
100 mg IM

2-4 hours

(M)

2.5-10 mg PO/SC/IM/IV q 812

48-72 hours
50-150 mg q3-4

pent/naloxone
150 mg po
combo: 1-2 tabs
30 mg SC/IM/IV
q3-4
0.8 mg po
0.3 mg IM

nalbuphine (Nubain)
tapentadol (Nucynta)

10-20 mg
q4

(D)
(P)

50-150 mg SC/IM q 3-4

(P)
(M)

300 mcg IM/IV q6-8

10 mg SC/IM/IV q 3-6

50, 75, 100

ER: 50, 100, 150, 200, 250

notes

8-12 hours
10 mg po
10-20 mg q 4-6
1 mg SC/IM/IV

$$$

cate
gory

2-4 hours

$$$

rectal
dosing

8-24 hours

$$

5, 10, 40, 5/5ml, 10/1ml ($0.33)

2, 8 SL

parenteral dosing

2-4 hours

$$$

50/0.5

Duration of
Action

10-30 mg q3-4

2 mg ($2)

50, 100, 10/1ml

po dosing

30 mg po

$$$

12, 25, 50, 75, 100 mcg/hr (75 approx

$20/d)

po Morphine
equivalent

Opana: 5, 10

pentazocine (Talwin)
buprenorphine (Buprenex,
Subutex)

COS
T

75 mg po

butorphanol (Stadol)

0.4 mg IM

sufentanil (Sufenta)

0.2 mg IV

50-100 mg q 4-6 2-4 hours

0.5-2 mg IV q3-4
Anesthesia 8-30 mcg/kg IV X
1

hepatic metabolism,
good for renal failure
transdermal dosing
toxic metabolites,
poor absorption
mixed
agonist/antagonist
mixed
agonist/antagonist
mixed
agonist/antagonist
mu receptor
antagonist

(M)
(P)

(M): morphines, (D): diphenylheptanes, (P): phenylpyridines