(SCHEMATIC DIAGRAM)

PREDISPOSING FACTORS Age (43 years old) Sex (Male) PRECIPITATING FACTORS Stressful Event (emotional guilt and conscience) Separation from family (Isolated) Human Brain Chemistry Unknown/Idiopatic Cause/Theoretical Bases Neuro-chemical Theory Human Brain (Central Nervous System)

Alteration of stimuli neurotransmission Disruption of communication between cells

Increased dopamine Alteration in frontal lobe

Decreased Serotonin Disruption of distribution of serotonin in pathway

Triggers the release of dopamine form the neuron into the synaptic space Binds to dopamine receptor on post synaptic neuron Stimuli

Frontal Lobe

Limbic

Temporal Lobe

S/Sx: Insomnia Feelings of Guilt Mania Loss of Appetite Hopelessness Psychotic Hallucination

Blocks the transport of CHON Inhibition of dopamine reuptake

Stimulation of dopamine receptors

Treatment: Haloperidol Biperiden CPZ Na Valproate Lithium Carbonate

Diagnostic Test: CBC Crea SGPT/SGOT

Dopamine builds up in the synaptic space

Excess dopamine continue to bind receptors

Stimulation of the post-synaptic neuron Increases dopamine distribution in the 4 major dopamine pathways

Mesolimbic Pathway disorganized

Mesocortical Pathway disorganized

Nigostriatatal Pathway disorganized

Tube Indufundibular Pathway disorganized

Schizoaffective Disorder

PROGNOSIS

With Medical Management: Psychotherapy and Counseling Nurse-Patient Interaction

Good Prognosis

Maintenance/Medication: Haloperidol Biperiden Chlorpromazine

Recovery

LEGENDS:

RISK FACTORS

PATHOLOGY

MANAGEMENT/DIAGNOSTIC TEST

LABORATORY TEST/RESULT

MANIFESTATIONS