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Dr Vidushi Sharma

MD (AIIMS), FRCS (UK)

Dr Suresh K Pandey
MS (PGIMER), ASF (USA)

SUVI EYE INSTITUTE KOTA, RAJ, INDIA Phone +91 9351412449 E-mail:suvieye@gmail.com Website: www.suvieye.com

Spectrum of Refractive Surgeries


REFRACTIVE SURGERIES CORNEA BASED LENTICULAR BASED

COMBINED(BIOPTICS)

-R.K. -PRK -LASIK -EPILASIK -LASEK -Conductive Keratoplasty -Corneal Inlays and rings

-Clear Lens extraction for myopia -Phakic IOL (IPCL) - Prelex Clear Lens Extraction with use of Multifocal IOLs

Combination of the two

HISTORY OF PHAKIC IOLs


Pioneers of Phakic IOL Choyce, Strampelli,

Barraquer conducted first ever trials using AC refractive lenses to correct high myopia in 1950s. But due to unacceptable complications such as loss of corneal endothelial cells, iris atrophy, PAS , these especially the angle supported lenses were phased out of the market.

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

HISTORY OF PHAKIC IOL


First model made by Fyodorov in 1980s

in Russia of a collar button configuration. First implant in Europe in 1993. Concept of soft phakic lens.

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota India

Types of Phakic IOLs

1.

An intra-ocular lens is placed inside the eye in front of the patients natural lens. These are available in three types
Anterior chamber angle fixated IOL Nuvita (Bausch & Lomb), Kelman duet, I care (corneal), Vivarte (Ciba vision) Iris supported phakic IOL Verisyse/ Artisan (AMO/Ophtec) Plate lens that fits between the iris & the crystalline lens Starr implantable contact lens (ICL), PRL (Ciba), and recently launched IPCL (Care Group India)
Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

2. 3.

Advantage of Posterior Chamber Phakic IOL (IPCL)


Behind the iris
Far from the endothelium (ECD) Excellent cosmesis (invisible to the eye) Close to the Nodal points of the eye Gain in retinal size image Greater effective Optical Zone (at the corneal plane)

Sulcus located
Stable location (allows for Toric design with same platform) Easy removable /exchangable

No fixations into tissues (iris)


Does not alter shape/remove tissue (corneal based procedures)

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

What Is IPCL?
IPCL is single piece posterior chamber phakic IOL, which can be inserted into the eye through sub 2.8mm incision. The lens is customized according to shape and size of each eye Widest power correction range from +10D to -25D with cylinder up to 8D Made from a Hybrid Acrylic material to ensure long term performance. 100% vegetarian Lens no porcine collamer inside

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL

Indications for IPCL


Age above 18 years Stable refraction for one year Patients not suitable for LASIK/LASEK due to high

powers or thin corneas AC depth 2.80 mm Endothelial count >2000cells/cumm No other ocular pathology

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL: An Option where LASIK is not Feasible


LASIK IS NOT INDICATED

WHEN
CCT such that minimum safe

bed thickness is not left(250270).Post op Corneal thickness should not be <410. Postop Cornea not too flat or steep.<36D or>49D(Poor Optics).

Contraindications of IPCL
Myopia other than axial myopia Corneal dystrophy/ Endothelial cell count

<2000cells/cu mm Anterior chamber depth less than 2.8 mm History of uveitis Presence of anterior/posterior synechiae Glaucoma or IOP higher than 20 mmHg Evidence of nuclear sclerosis or developing cataract Personal or family history of retinal detachment Diabetes mellitus
Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Pre-op assessment for IPCL


Refraction Objective & subjective acceptance at

12mm vertex distance Anterior chamber depth (ACD) from corneal endothelium Anterior & posterior segment examinations K-reading & Topography Intra-ocular pressure White to white measurement Specular microscopy (if possible)

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

INDICATIONS FOR IPCL


Indication in

Myopia
Myopia of -3 to -25 Dioptres

Astigmtism up to 6 Dioptres Thin Corneas Hyperopia Presbyopia (Multifocal IPCL)

Measurement of white to white diameter (Clear Cornea to Clear Cornea)


Using Orbscan, UBM or digital calipers
Add 0.5 mm to horizontal WW measurement for IPCL

overall length IPCL too short lens vault less, exposes to risk of Anterior capsular cataract IPCL too long lens vault exceeds angle crowding closed angle glaucoma

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

White-To-White Measurement Using Calipers

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

White-To-White with calipers


Measurements of the White-to-white distance using a

caliper has been proven to be a simple but reliable method.


Please watch the following points:

Make sure that the caliper is well calibrated. Pre-treat the eye with anaesthetic drops Take the measurement under the microscope with the patient in the supine position Read the caliper measure on a ruler
Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Pearls: White-To-White
Use Orbscan to validate caliper measurement:

Automated & Manual: Eye Metrics Tool If you use the IOL-Master or similar make sure you validate the outputs: some reports of IOL-Masters overestimation of the wtw Be careful with pterygium, pigmented area around the cornea etc. Evaluate discrepancies between measuring devices and between eyes: both eyes should have about the same wtw

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL and Sizing


Ideal sized IPCL will provide a vault (central distance

between anterior surface of the crystalline lens and posterior surface of the IPCL) within a range of 0.250 to 0.750 mm ( CT to 1 & CT) . An undersized IPCL (less than 0.125 mm vault) may increase the risk of anterior subcapsular opacification.
An oversized IPCL (more than 1 mm vault) may push the iris forward and close the angles which could lead to IOP rise and Iris malfunction.

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL and Sizing: Vault

If the IPCL is properly sized (WtW & ACD are critical) a separation will exist between the post surface of the IPCL and the ant suface of the human lens. We use the term - Vault to refer to this space

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL inside the Eye

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL Vault

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL Vault

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL IMPLANTATION PRE-OPERTIVE PREPARTION

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Peripheral Iridotomies (YAG PIs)


One to two weeks pre-op perform PIs Provides an outlet for aqueous flow

11:00

1:30

around the lens

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Peripheral Iridotomies (PIs)


The PIs must be large & patent: at least 0.8 to 1 mm in diameter Location: 10.30 oclock and 1.30 oclock, or (90 ) apart in the superior iris Inadequate PIs can cause early post-op complications (IOP rise, pup block)

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Dilatation- Immediate Pre-Op


Minimum 8 mm dilation. Avoid Cyclopentolate. Pre-treat: Tropicamide, Phenlyephrine and NSAID

Borderline size

Well dilated pupil

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Topical Anesthesia- Immediate PreOperative


Topical Anesthetic
per routine

IV/PO Sedation
as necessary

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Immediate Pre-Operative
Cataract prep and drape Normal sterile technique

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

The IPCL Injection System (Care Group India)


The IPCL is injected through the

injectors The IPCL cartridge requires a 2.8mm incision

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Loading the IPCL


The IPCL is marked to ensure proper Orientation in the eye as it unfolds

Hole on Left Side (Leading Haptic)

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Loading the IPCL Observe the IPCL for proper orientation in the cartridge
Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Surgical Technique

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL PREPARATION
Step 1. Open the Cartridge and Injector fill the Cartrige

with HPMC Step II. Open the IPCL Container Step II. Gently Hold the IPCL with McPherson Forceps near haptics Step III: Check the Orientation of IPCL (Hole at Left Side, 2 holes superiorly) Step IV: Place the IPCL in the Cartridge Step V: Put the Cartridge in injector
Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Surgical Technique of IPCL


- Two Paracentesis

- Viscoelastic injection
- Temporal, clear corneal incision - Injection of IPCL

- Injection of viscoelastic on top of IPCL


- Positioning of IPCL behind iris - Irrigation (and aspiration) of viscoelastic - (Constriction of pupil) - 2-4 hours post-op check

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL Surgical Technique


Remember that you have always removed the crystalline lens Now you are preserving the

crystalline lens... Nothing more than a series of steps you are already comfortable with Execution of each step is more critical

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Paracentesis for IPCL


degrees away from the main incision
Remember that is difficult to make a

Carefully make two paracentesis 90

paracentesis after the main incision

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Inject Viscoelastic (2% HPMC)


Inject 2% HPMC type viscoelastic

Maintain visible chains


Do not overfill

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Clear Corneal Incision


Slow, controlled entry Use knife that you are

comfortable with

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL Injection
Leading Left Landmark (LLL)

Place cartridge just inside

incision

Inject slowly until the leading

left landmark is visible

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL Injection
Do not fully inject the IPCL until you

visualize the landmarks


You still have control as long as the IPCL

remains in the cartridge

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL Injection (How to Identify Upside Down position?


What if this IPCL unfolded with the landmark on the Right? Upside down IPCL

WAIT, WAIT, WAIT

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Manipulating the Haptics


- Put viscoelastic on top of the lens to give yourself more room - Manipulate in the periphery via the paracentesis - Do the distal haptics first while the pupil is maximum dilated - Avoid going across the central lens - Manipulate on the body of the IPCL, avoid the optic

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Viscoelastic removal
Thoroughly

remove viscoelastic with BSS on a cannula or use your I/A instruments


Slight incisional

pressure while irrigating

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Constrict Pupil with Pilocarpine


Make sure

footplates are behind Iris

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

If you prefer, you can leave the

pupil dilated to allow aqueous and possibly remaining viscoelastic to pass in front of the IPCL.

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

2 hour post-op exam


IOP check
use caution if IOP > 24 mmHg or 10 mmHg higher than pre-op

IOP Elevation - Retained Viscoelastic burp and recheck - Non-patent Iridotomies back to the Yag laser Check PIs
ACD should look deep

Check IPCL vault


low vault is common at 2 and 24 hour check

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Post-op Medication
Follow your normal cataract routine Antibiotic 3-4x / day for one week Steroids or NSAID 3-4x / day for 2 weeks (taper if steroids) Systemic Acetazolamide for 3 days
Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

IPCL Loading

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

VIDEO OF IPCL
http://www.youtube.com/watch?v=GmyMkyA9ZCE

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

VIDEO OF TORIC IPCL


http://www.youtube.com/watch?v=GPLyfuPwfbg

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

VIDEO OF TORIC IPCL


http://www.youtube.com/watch?v=rltHvJ3pnbs

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Toric IPCL Marking on Slit lamp

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Note the Marking on Cornea

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Axis Marking during Surgery (0-180 Degree)

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Dr Vidushi & Dr Suresh Pandey Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Final Alignment of Toric IPCL

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

RECENT ADVANCES IN IPCL SIZING


With the advancements in anterior segment imaging ,

ultrasonic biomicroscopy , Optical coherence tomography and Scheimpflug imging ,valuable information is now provided about anterior segment anatomy for phakic Intraocular lenses(IPCL) for correction of moderate to high refractive errors.

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Advantages of IPCL
The procedure is reversible unlike LASIK
The quality of vision is usually better It creates a small corneal incision so astigmatism is

minimum Corneal tissue is not removed ,hence adequate tear layer Reduction of risk of optical distortions an higher order aberrations

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Complications of IPCL
IPCL decentration
Pupillary block Pigment dispersion

Subcapsular cataract
Potentially endophthalmitis

Dr Vidushi & Dr Suresh Pandey

Advantages of phakic IOLs over laser corrective procedures


A higher range of refractive errors can be corrected Reversible: Phakic IOL implantation is a potentially

reversible procedure Safe: No structural changes are induced. Hence it is safe in any eye with high error & also thin corneas. Better quality of vision: Quality of vision (contrast sensitivity) is better than the laser refractive procedures in eyes with higher refractive errors and no induced higher order aberrations. There is also a considerable improvement in BVCA with these lenses because of the magnification effect. Highly skilled procedure: Prevents misuse of the procedure.
Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Bioptics

Bioptics is a combination of phakic IOL and LASIK. Bioptics is done for the correction of the residual spherocylindrical power when a spherical implant is used.

Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

RK: Started in 1978, peaked in 1994. PRK: Started in 1984, peaked in 2006. LASIK: Started in 1989, Has LASIK peaked?? LASIK Procedure losing share in major markets. IPCL: IPCLs implant gaining popularity world wide.
Dr Vidushi & Dr Suresh Pandey SuVi Eye Institute, Kota ,India

Dr Vidushi Sharma
MD (AIIMS), FRCS (UK)

Dr Suresh K Pandey
MS (PGIMER), ASF (USA)

SUVI EYE INSTITUTE KOTA, RAJ, INDIA Phone +91 9351412449 E-mail:suvieye@gmail.com Website: www.suvieye.com

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