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Some armies in the medieval times used the disease for biological warfare. For example they would send people with the Bubonic plague into cities they were in war with and infect and decrease their population. The medieval doctors recommended moving from the plagued cities, staying away from rats and insects, and being more sanitary. When people started moving away from the plagued cities, they moved into lands that didnt have the disease and started the disease there. So basically the world was in a cycle of disease. Plague still exists in various parts of the world. In 2003, more than 2,100 human cases and 180 deaths were recorded, nearly all of them in Africa. The last reported serious outbreak was in 2006 in the Democratic Republic of the Congo in Central Africa, when at least 50 people died. The United States, China, India, Vietnam, and Mongolia are among the other countries that have confirmed human plague cases in recent years. Most people survive if they're given the correct antibiotics in time. Good sanitation and pest control help prevent plague outbreaks since they need crowded, dirty, rat-infested conditions to really get going. Some people today still fear that some nation can find a way to combine the infection, and make multiple supplements of the bubonic plague, put it into a nuclear bomb and affect the world again. I think that this is one of the most major turning points in history! It changed the world for hundreds of years! It killed and extinguished 1/3 of the worlds population and changed history forever!