PLATFORM BIOREACTORS TO

FACILITATE REGENERATIVE
MEDICINE EFFORTS
Lee Sierad
lsierad@g.clemson.edu
OUR GOALS
Provide a system that allows researchers to test
and create living cardiovascular replacements
Heart valves, blood vessels, etc
Support regenerative medicine research by
adapting our products and technologies to fit
each researchers specific needs
MORE THAN THE STATUS QUO
Standard 2D and 3D culture environments are
inadequate models for whole-tissue culturing
Apply limited mechanical forces
Directed at cellular response, not tissue development
All tissue-engineered products need pre-conditioning
Cardiovascular bioreactor options are scarce
Most created by research labs dont fully represent
the blood flow seen in the body
No adequate commercial option
WE HAVE A COMPETITIVE ADVANTAGE
Sterile
Environment
Stroke
Volume
Pulse
Rate
Simplicity
of assembly
<30 minutes
TISSUE ENGINEERING & REGENERATION IN 2016
Global Market
$89.7Billion
U.S.
$40.4 Billion
Europe
$36.1 Billion
Rest of World
$13.1 Billion
Cardiovascular
Devices
$1.7 Billion
Source: BCC Research 2012
ADVANTAGES FOR APTUS MARKET ENTRY
Seven years of university research
Third-generation, sophisticated, platform system
made for easy assembly and use
Extensive experience and knowledge in the
field for use in customer support
IP portfolio covering trademarks, copyrights,
and three pending patents
POTENTIAL FOR EXPANSION
Additional modules
Pulmonary/aortic valves
Small diameter blood vessels
Aortic aneurysms
Mitral valves
TAVI implantation tests
Customization and service
Drug and diagnostics testing
WHATS NEXT?
File patents and determine license agreements
with Clemson University Research Foundation
Fulfill first order for a waiting customer then
finalize additional modules
Secure initial funding through local and
national small business grants
Looking for additional partners to expand our
applications, market segments, network, and
research capabilities
Looking for additional partners to expand our
applications, market segments, network, and
research capabilities
WHATS NEXT?
Lee Sierad
lsierad@g.clemson.edu
864-986-0533