Echocardiographic Protocol for Thoracic Aortic Aneurysms
The initial evaluation for a thoracic aortic aneurysm by echocardiogram should show all the structures of the heart, including the heart valves and the entire ascending thoracic aorta. It is critical that the aortic diameter be measured accurately and standard nomograms for aortic diameter be used that are based on the patients age and body surface area. These nomograms are attached (Roman et al. Am J Cardiol 1989; 64:507-512).
We strongly recommend obtaining 4-point measurements of the ascending aorta at the following levels shown on the figure below: (1) annulus; (2) mid-sinuses of Valsalva; (3) supraaortic ridge or sinotubular junction; (4) the proximal ascending aorta. Four point measurements are important for the following reasons: (1) some aneurysms enlarge initially at the sinuses of Valsalva (e.g., Marfan syndrome, Loeys-Dietz syndrome) while other spare the sinuses and involve the ascending aorta (MYH11 mutations); (2) standardized measurement allow for more accurate assessment of the aortic diameter over time.
Recommendations for measurement: (1) First use parasternal long-axis view to generate m-mode from mid sinuses of Valsalva and measure diameter (described as m-mode measurement). (2) Use parasternal long axis view at the end of diastole (onset of QRS complex) to measure the 4 sites on the figure. Measurements are made from leading edge to leading edge except at the hingepoints of the aortic valve cusps (annulus), where measurements are made from trailing edge to leading edge. If the rhythm is regular, average the measurements from 2-3 consecutive beats. If the rhythm is irregular, average the measurements from 5-10 consecutive beats. (3) Use graph for infants and children (ages up to 15 years) for comparison to normal and plot both measurements (sinuses of Valsalva and supraaortic ridge) requested. Post puberty, may consider using graph for adults (< age 40 or > 40). (4) Inspect aortic valve for morphology (trileaflet, bicuspid) and function (by Doppler) for assessment of insufficiency and/or outflow gradient.
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