Alzheimers Disease

By Irvin Safavi and Jake Lopez

Irvins Grandma Jakes Grandpa
Alzheimers or AD is a disease, that contributes to Dementia. It is
caused by a abnormal plaque build up, in the brain. It affects 5.1
million Americans, every year.

This is a huge problem, that unfortunately has no cure.

The Science
No one knows what is connected to AD.
It may be a part of complex changes
Genetics is a possible issue: APOE 40%
Interferes with cell communication (plaque build up)



The Science Continued
Neurons lose their ability to function and communicate
with each other, and die.
Not reversible and creates Nerve damage, it is dangerous.
Its a progressive brain disease that slowly destroys thinking
skills, and to carry out the simple tasks.
Damage to the brain starts a decade or more before
problems become evident.
Neurofibrillary tangles are found in an AD brain.
How big is the Problem? Is it getting worse?
Estimated to affects over 5,000,000 people
Every year, the symptoms get worse.
Eventually it has affected 30% of the brain.
Its 6th most killing disease.
50% of age 80, have AD.
The issue is getting worse; unknown why.




http://www.cdc.gov/nchs/data/databriefs/db116_fig2.png
Causes
Not part of normal aging.
Possible connection to heart disease, high blood pressure.
Mutated genes
Brain Damage:
Cellular Debris,
Protein plaques, and
Collapsed, clumped
microtubules.
Tau protein cluster,
malfunctioning tangles
Amyloid plaques and
Neurofibrillary tangles



http://mydementedmom.files.wordpress.com/2012/12/screen-shot-2012-12-02-at-2-52-18-pm.png
Symptoms
Its mostly memory loss, but other symptoms
include:
Confusion or ignorance, depression,
talking about
odd things,
Lastly emotionality,
for no reason.

http://www.alzheimer-europe.org/Research/Value-of-Knowing/Public-knowledge-of-Alzheimer-s-disease
Symptoms of the Stages
AD splits into three stages.
Mild AD patients get
short-term memory,
bad judgment of things,
and personality changes.
During Moderate AD, the person gets
increased memory loss,
the inability to learn new things,
hallucinations, impulses, and paranoia.
The final stage of AD, is Severe Alzheimer's Disease.
This is when AD effects more than just memory-related parts of
the brain.
Inability to communicate,
weight loss, seizures, skin infections,
groaning, and death.
http://www.leadingage.org/Advice_for_Caregivers_of_People_
with_Alzheimers_Disease.aspx
THE SOLUTION
There will be no cure for Alzheimers Disease, for a long
time.
However, there are some medications that can slow down
the effects.
Four approved drugs are
Donepezil,
Rivastigmine,
Galantamine, and
Memantine.

The drugs only work temporarily.
http://www.uspharmacist.com/content/c/26130/?t
=alzheimer%27s_and_dementia
Why do we care?
Imagine this:
Family members dont remember you.
Soon enough, you wont remember
them,
right now,
your childhood,
and hardly know who you are.
Imagine one day,
you wake up in a hospital,
you dont know how you got there.
You will have seizures, hallucinations
until you die.
This will happen to half of us, and in maybe in a
few decades, that number will increase largely.
http://insaniroefliana.com/wp-
content/uploads/2014/03/cara-mencegah-alzheimer.jpg
Food that helps memory (Ways to
prevent AD)






Vitamin formula should contain
folic acid and vitamin C.
Alzheimers disease are not
just dependent upon your genes,
your lifestyle has a huge impact as
well.
Eat These:
20% good fats. Items like virgin olive oil, and avocado.
40% lean proteins, like fish.
40% complex carbohydrates. Including blueberries, spinach, and
seaweed.
http://healthfindersmn.org/reason/images/245470.jpg
Acknowledgments
Special Thanks to Ms. Oefinger, Ms. Cerni, and all these websites
Below:
Bibliography
""About Alzheimer's Disease: Causes." National Institute on Aging. N.p., n.d. Web. 11 Mar. 2014.
<http://www.nia.nih.gov/alzheimers/topics/causes>.
"About Alzheimer's Disease: Symptoms." National Institute on Aging. N.p., n.d. Web. 12 Mar. 2014.
<http://www.nia.nih.gov/alzheimers/topics/symptoms>.
"About Alzheimer's Disease: Treatment." National Institute on Aging. N.p., n.d. Web. 12 Mar. 2014.
<http://www.nia.nih.gov/alzheimers/topics/treatment>.
"Alzheimers Disease." Alzheimers Disease. N.p., n.d. Web. 13 Mar. 2014.
<http://learn.genetics.utah.edu/content/disorders/multifactorial/alzheimers/>.
"Alzheimer's Disease." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 23 Feb. 2011. Web. 13 Feb.
2014. <http://www.cdc.gov/aging/aginginfo/alzheimers.htm>.
"Alzheimer's Disease: Unraveling the Mystery." National Institute on Aging. N.p., n.d. Web. 12 Mar. 2014.
<http://www.nia.nih.gov/alzheimers/publication/part-3-ad-research-better-questions-new-answers/looking-causes-ad>.
Gandy, Sam. "Alzheimer's Disease." World Book. N.p., n.d. Web. 04 Feb. 2014.
Hamilton, Jon. "Alzheimer's 'Epidemic' Now A Deadlier Threat To Elderly." NPR. NPR, n.d. Web. 14 Feb. 2014.
<http://www.npr.org/blogs/health/2013/03/19/174651566/alzheimers-epidemic-now-a-deadlier-threat-to-
elderly?ft=3&f=111787346&sc=nl&cc=es-20130324>.
Kennedy, Angus. "Alzheimer Disease." Grolier Multimedia Encyclopedia. N.p., n.d. Web. 11 Feb. 2014.
N.p., n.d. Web.
"About Alzheimer's Disease: Causes." National Institute on Aging. N.p., n.d. Web. 11 Mar. 2014.
<http://www.nia.nih.gov/alzheimers/topics/causes>.
"About Alzheimer's Disease: Symptoms." National Institute on Aging. N.p., n.d. Web. 12 Mar. 2014.
<http://www.nia.nih.gov/alzheimers/topics/symptoms>.
"About Alzheimer's Disease: Treatment." National Institute on Aging. N.p., n.d. Web. 12 Mar. 2014.
<http://www.nia.nih.gov/alzheimers/topics/treatment>.
"Alzheimers Disease." Alzheimers Disease. N.p., n.d. Web. 13 Mar. 2014.
<http://learn.genetics.utah.edu/content/disorders/multifactorial/alzheimers/>.
Acknowledgments Continued!
"Alzheimer's Disease." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 23 Feb. 2011. Web. 13
Feb. 2014. <http://www.cdc.gov/aging/aginginfo/alzheimers.htm>.
"Alzheimer's Disease: Unraveling the Mystery." National Institute on Aging. N.p., n.d. Web. 12 Mar. 2014.
<http://www.nia.nih.gov/alzheimers/publication/part-3-ad-research-better-questions-new-answers/looking-causes-ad>.
Gandy, Sam. "Alzheimer's Disease." World Book. N.p., n.d. Web. 04 Feb. 2014.
Hamilton, Jon. "Alzheimer's 'Epidemic' Now A Deadlier Threat To Elderly." NPR. NPR, n.d. Web. 14 Feb. 2014.
<http://www.npr.org/blogs/health/2013/03/19/174651566/alzheimers-epidemic-
"Alzheimers Disease." Alzheimers Disease. N.p., n.d. Web. 13 Mar. 2014.
"Alzheimers Disease." Alzheimers Disease. N.p., n.d. Web. 20 Mar. 2014.
"Alzheimer's Disease Fact Sheet." National Institute on Aging. N.p., 13 Feb. 2014. Web. 27 Feb. 2014.
"Behavioral Symptoms | Alzheimer's Association." Behavioral Symptoms | Alzheimer's Association. N.p., n.d. Web. 12 Mar. 2014.
DeSimone II, Edward M., and Laura Viereck. "Alzheimer's Disease: Increasing Numbers, But No Cure." USPharmacist.com. N.p., 20 Jan.
2011. Web. 28 Mar. 2014.
Greytone. "Advice for Caregivers of People with Alzheimer's Disease." - LeadingAge. N.p., 27 Jan. 2014. Web. 31 Mar. 2014.
Hamilton, Jon. "Alzheimer's 'Epidemic' Now A Deadlier Threat To Elderly." NPR. NPR, n.d. Web. 28 Feb. 2014.
Http://mydementedmom.files.wordpress.com/2012/12/screen-shot-2012-12-02-at-2-52-18-pm.png. N.d. By My Demented Mom. Web.
Http://www.cdc.gov/nchs/data/databriefs/db116_fig2.png. N.d. By CDC .. Gov. Web.
"PILLAR 1: DIET & SUPPLEMENTS." Diet & Supplements. N.p., n.d. Web. 01 Apr. 2014.
Pointblog, Media .. 1fecaf144abd40d0bc5ecc0ae2b52b7a_1058328.jpg 769x768 Pixles. N.d. N.p.
"Public Knowledge of Alzheimer's Disease." - Value of Knowing. N.p., 13 July 2011. Web. 28 Mar. 2014.
Silverman, Jacob. "Alzhemer's Overview." HowStuffWorks. N.p., n.d. Web. 28 Mar. 2014.
"Healthfinders Collaborative." Healthfinders Collaborative. N.p., n.d. Web. 03 Apr. 2014.


Thank You for Watching!