Titrimetric analysis

This involves removing small portions (aliquots) of the reacting mixture at

regular intervals. These aliquots are usually added to another reagent, which
immediately stops or quenches the reaction.
Alternatively, the reaction is slowed by immersing the portion in an ice bath,
so that there are no further changes to the concentrations in the reacting
mixture until further analysis can be carried out. The quenched aliquots are
then titrated to find the concentrations of known compounds in them.
In a reaction in which acid is being used up, titration could be carried out with
a standard solution of sodium hydroxide. A similar technique of titrimetric
analysis is useful for investigating the reaction between iodine and propanone
(fig. 1.1.5) , which is catalysed by acid. The samples are run into excess sodium
hydrogencarbonate to stop the reaction. By titrating with sodium thiosulfate you
can measure the concentration of iodine in the reacting mixture (see page 14) :
CH
3
COCH
3
(aq) + Iiaq) CH
3
COCH
2
I(aq) + H+(aq) + I-(aq)
2Na
2
S
2
0
3
(aq) + Iiaq) Na
2
S
4
0
6
(aq) + 2Nai(aq)