Grade and Topic: 10, Genetic mutations and disorders Length of Lesson: 1 hour___ Mentor Teacher: Dr. Cornelius School: University of Memphis___
LESSON DESCRIPTION/SUMMARY: In this lesson, students will integrate information covered in a previous lesson on genetic mutations to create an informational brochure about a specific genetic disorder. Students will be paired and assigned a genetic disorder. Students will use Microsoft PowerPoint to create a brochure that includes information about the mutation that causes the disorder, how the mutation affects the body, and the symptoms it causes for an affected person. Students will make sure all information that they want to share with the class is on the brochure. Students will also plan how they will work with their partners to present the brochures to their classmates in the next lesson.
UNIT/CHAPTER OBJECTIVE/GENERALIZATION/BIG IDEA: The lesson on genetic mutations and human genetic disorders is part of a unit on heredity exploring the mechanisms by which organisms reproduce and transmit hereditary information.
LESSON OBJECTIVE: The student will be able to explain in-depth information about a specific genetic disorder. The student will have an understanding of what type(s) of genetic mutations may be the cause of genetic disorders. The students will participate in groups of 2 in the creation of an informational brochure using Microsoft PowerPoint as well as in the planning of presentation of the brochure to classmates.
STANDARDS ADDRESSED: Common Core Standards: Tennessee Biology Standard 4 Heredity Course Level Expectation CLE 3210.4.6 Describe the connection between mutations and human genetic disorders. Check For Understanding 3210.4.6 Design an informational brochure to describe a human genetic disorder. State Performance Indicator SPI 3210.4.8 Determine the relationship between mutations and human genetic disorders. ISTE Standards: 1. Creativity and Innovation b. Create original works as a means of personal or group expression
2. Communication and Collaboration a. Interact, collaborate, and publish with peers, experts, or others employing a variety of digital environments and media
3. Research and Information Fluency b. Locate, organize, analyze, evaluate, synthesize, and ethically use information from a variety of sources and media
5. Digital Citizenship a. Advocate and practice safe, legal, and responsible use of information and technology b. Exhibit a positive attitude toward using technology that supports collaboration, learning, and productivity
6. Technology Operations and Concepts a. Understand and use technology systems
MATERIALS: Textbook Computer Microsoft PowerPoint Internet Technology Integration At the computer, students will create an informational brochure about a genetic disorder using Microsoft PowerPoint. Students will access the internet to get information or images that they would like to include in their brochures.
BACKGROUND and RATIONALE: The key concepts for this lesson are genetic mutations and human genetic disorders. The critical academic language for this lesson includes the following terms: mutation, missense, nonsense, insertion, deletion, duplication, frameshift mutation, repeat expansion. This lesson builds on the previous lesson on genetic mutations. In the previous lesson, the teacher gave an introduction to and lecture on the topic of genetic mutations. Students were introduced to all types of mutations and other relevant material in this lesson. In the subsequent lesson, students will present their informational brochures to their fellow classmates. Students will teach/learn from each other about several human genetic disorders. It may be necessary to plan differentiated activities for any students who fall behind and do not understand the material or for any student who may wish to go further into detail on the topic.
PROCEDURES AND TIMELINE: Introduction: Yesterday we learned about genetic mutations. We learned that there are several different types of mutations and also that they can have big effects on organisms, depending on the type and location of the mutation. However, we didnt talk about any specific genetic disorders. Im sure that if we all think for a minute or two we can come up with at least one person that we know of who suffers from a genetic disorder. Maybe your mom has Huntington disease, for example. Wouldnt you like to know why she suffers from that disorder? What tiny, microscopic mistake in DNA replication has caused your mother to be affected? How is that disease transmitted; can you get the disorder? What symptoms does your mom suffer from, or what symptoms may she suffer from in the future? And how can doctors help her? Are there medications or treatments out there? A lot of people dont think about these things until it becomes personal. So I want everyone to think about someone you may know and come up with an idea or two of a disorder you would like to learn about. Then were going to work in pairs to research some disorders. Each pair is then going to open up Microsoft PowerPoint and create an informational brochure about the disorder you researched. Tomorrow, each pair is going to present those brochures to your classmates. You all get a chance to learn about a disorder that may be important to you personally, and then you get to teach your peers about that disorder. Procedures: First 10 minutes- The teacher will give the introduction. Students will brainstorm some disorders that may interest them. The teacher will pair students based on their interests in the same disorders as much as is possible. Next 20 minutes- The students will move to the computers and open the internet. Students will look up the answers to the following questions that will be listed on a performance think sheet: What type of genetic mutation causes this disorder? How is this disorder transmitted among family members? What are the symptoms of the disorder? What treatments or medications are available for the disorder? (Answers to all questions will be filled in on the think sheet before the brochures are made.) Students will also look up any other information they find relevant or interesting about their disorder. Last 30 minutes- The students will open Microsoft PowerPoint and use the program to create informational brochures. Students will follow the following instructions for getting a brochure template in PowerPoint: Click on the Design tab. Select a theme for the presentation that isnt too flashy. Click on the slide. Press Ctrl-A. Press Delete. Click on the Insert tab. Click Table. Choose a 3x1 table. Click on the table. Click Layout. Enter 7.5 for height and 10 for width. Click the Home tab. Click the New Slide drop down. Select Duplicate selected slides. Students will then enter text and/or graphics into the three columns to lay out their brochures as they see will best present the information. Students should save this brochure as well as print a copy to turn in before the end of class. Closure: Students will give a copy of their brochure to the teacher as well as their filled out think sheets. Students will also discuss with their partners how their class presentations will go and who will talk about which topics. This will allow students to be prepared to present in the subsequent lesson.
ASSESSMENT EVIDENCE: Student Product Description Students will produce a tri-fold brochure in Microsoft PowerPoint. The brochure should provide the appropriate information about a chosen genetic disorder. Answers to all questions listed above should be incorporated. The brochure must also be designed well so that it is easy to read but is also creative and original. Rubrics-
Criteria for Participation Grade: Unsatisfactory Satisfactory Think Sheet Did not find and fill out the answers to questions on the think sheet. Located all answers to questions on the think sheet and filled out the think sheet. Computer Work Did not actively participate with internet research or with creation of brochure in Microsoft PowerPoint. Actively participated with internet research and with creation of brochure in Microsoft PowerPoint.
Criteria for Brochure Grade: Unsatisfactory Satisfactory Required information Explanations of answers to required questions are not all present. Explanations of answers to required questions are all present. Layout The layout/background was not appealing and detracted from the information. The layout/background was appealing and enhanced the presentation of information. Graphics No meaningful graphics were used. At least one meaningful graphic was used. Spelling and Grammar There were at least two spelling or grammar errors in the text on the brochure. There were less than two spelling or grammar errors in the text on the brochure.