Hernandez 1

Jessica M. Hernandez
Professor Debra Dagher
UWRT 1102
13 October 2014
Double Entry Journal of Peer Reviewed Article
Article Citation: Burgmer M, Rehbein MA, Wrenger M, Kandil J, Heuft G, et al. (2013) Early Affective
Processing in Patients with Acute Posttraumatic Stress Disorder:
Magnetoencephalographic Correlates. PLoS ONE 8(8): e71289. doi:10.1371/journal.pone.0071289

Page Number /Quote

1, chronic PTSD
1, However, it remains unknown if the
severe trauma.
1, showed an enhanced PFC response to
high-arousing pictures btween 60-80 ms.
1, All aspects of the trauma including
cognitions, emotions, sensory, and
physiological responses, are stored as
nodes in a fear network
1, excitement of a single element is
sufficient to activate the whole network
and to initiate a fear reaction
1, Several functional brain imaging
studies revealed brain areas involved in
the trauma network
2, disturbed prefrontal cortex function
was recorded
List of areas of brain mentioned in text:
occipital cortex, superior parietal areas,
dorsomedial & R orbital PFC, L occipitotemporal & bilateral orbitofrontal cortex,
R dorsolateral & temporal cortex, L
temporo-parietal cortex, bilateral
dorsolateral & ventro-central prefrontal
cortex

Reflection/Comments
What is the difference between chronic
and regular diseases?
Possibly same to what Im trying to look
into
What type of measurement is ms? What
does 60-80 ms mean?
Interesting, maybe something to look
more into

Similar to a memory triggered by a smell

or noise

Are these possibly the same areas that

cause/activate with depression?

Look into original PFC function

Look into what these areas do and how

changes to them cause difference in
reactions from patients and controls

For the highlighted terms look up what

changes in text mean

Hernandez 2
Jessica M. Hernandez
Professor Debra Dagher
UWRT 1102
13 October 2014

Page Number /Quote

2, It was concluded that such heightened
PFC responsiveness displays a rapid
threat detection mechanism activating a
primary orienting response towards
threatening stimuli, while the reduced
responses in sensory areas reflect a
subsequent avoidance reaction.
2, All walk-in patients indicated that the
traumatic event had taken place between
13 and 52 days (mean:25 days) before
seeking treatment
2, the Clinical Administered PTSD Scale
(CAPS) Hamilton Anxiety and
Depression Scale (HADS)
4, Four patients fulfilled criteria of a
comorbid major depression of moderate
severity
5, This finding supports the
interpretation that patients and controls
differentially recruit frontal or visual
areas in the processing of emotional
stimuli during EPN-m [magnetic early
posterior negativity]
6, One-sided t-tests indicated a greater
activation for high arousing than low
arousing in patients and (by trend) greater
responses toward low-arousing than higharousing pictures in controls *differnces
in levels or arousing and valence defined
on page 1*

Reflection/Comments
I believe this is referring to the fight or
flight instinct that is honed through
similar traumatic experiences

What counts as a traumatic event?

How would the results be different if the
time between event and treatment were
longer? *study T-E=man-made phys viol*
Are these scales universal or German
specific?
What does comorbid mean?
Is this another level like chronic? If so
what are all the levels?
Is this referring to a change in the
processing of visual information between
controls and patients?

What do one-sided t-tests test?

What does this tell us about the patients
and controls.

Hernandez 3
Jessica M. Hernandez
Professor Debra Dagher
UWRT 1102
13 October 2014
Anything not used from the text either only enhanced my understanding of the process the study took or
was technical jargon that was not understood but didnt need to be understood for comprehension of the
study/results.