Manufacturer

Reckitt Benckiser
Distributor
Reckitt Benckiser
Contents
Sodium alginate, sodium bicarbonate, calcium carbonate.
Indications
Gaviscon brings fast, soothing and long lasting relief. It is used for the treat
ment of symptoms of gastroesophageal reflux (GERD) eg, acid regurgitation, heart
burn and indigestion due to reflux of stomach content. It is safe for pregnant w
omen and breastfeeding mothers.
Dosage & Administration
Chewable Tablet: Adults and Children >12 years: 2-4 tablets. The tablet must be
chewed thoroughly before swallowing.
Oral Liquid: Adults and Children >12 years: Take 10-20 mL (two to four 5 mL spoo
nfuls). Children 6-12 years: Take 5-10 mL (one to two 5 mL spoonfuls). Administe
red after meals and at bedtime.
Contraindications
Hypersensitivity to any of the ingredients of Gaviscon as very rare difficulty i
n breathing and skin rashes have occurred.
Storage
Chewable Tablet: Store below 30C. Oral Liquid: Store at room temperature not exce
eding30C.
Shelf-Life: 2 years.
Description
Each chewable tablet contains sodium alginate 250 mg, sodium bicarbonate 133.5 m
g and calcium carbonate 80 mg. Per 10 mL liquid contains sodium alginate 500 mg,
sodium bicarbonate 267 mg and calcium carbonate 160 mg. Gaviscon chewable table
t is aluminum-, sugar-, lactose- and gluten-free. Gaviscon peppermint liquid is
sugar-free and gluten-free.
Mechanism of Action
Sodium alginate reacts with gastric HCl to produce a low density viscous raft th
at floats on top of the stomach contents to physically impede their reflux back
into the esophagus. Thus, the acid pepsin, bile and food all remain in the stoma
ch.
The bicarbonate reacts with the HCl to produce bubbles of carbon dioxide that be
come entrapped in the raft allowing it to float on the stomach contents. The inc
lusion of calcium carbonate in some formulations means that the raft has conside
rable strength, since a cross-linked lattice is formed involving calcium ions re
leased on reaction of calcium carbonate with HCl and the guluronate dimers in th
e alginic acid. The raft remains on top of the stomach contents until the stomac
h empties.
Gaviscon