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CK-BB

Modani izoenzim
Uzroci povienih vrijednosti:
1.

Cerebrovaskularni inzult (CVA)

2.

Subarahnoidalno krvarenje (subarachnoid hemorrhage)

3.

Neoplazme: prostate, gastrointestinalnog trakta, mozga, ovarija, grudi-dojki,

plua (neoplasms: prostate, GI tract, brain, ovary, breast, lung)


4.

Teak ok (severe shock)

5.

Infarkt crijeva (bowel infarction)

6.

Hipotermija (hypothermia)

7.

Meningitis

CK-

:
1. (CVA)
2.
3. : , , , ,
,

4.
5.
6.
7.

3.1.8 BB Isozyme of Creatine Kinase


CK-BB is predominantly found in the CNS, but is also in the gastrointestinal system,
uterus, and vascular wall, and has been suggested to be a marker of adenocarcinomas.
[151] The half-life of CK-BB is 1-5 hours. In CSF samples, a correlation between
outcome (GOS) and lesion size has been found with respect to CK-BB levels.[164]
However, no correlation was found when these measures were compared with serum
levels of CK or CK-BB.[138,165] The lack of diagnostic accuracy in serum samples is
thought to be due to either low transfer rates of CK-BB from the CSF to the serum, or
its rapid elimination from the serum.

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