CHALK MIXTURE

Antacid
USES:
Antacid Gastrointestinal Agent
INDICATIONS:
Indigestion and Dyspepsia.
CONTRAINDICATIONS:
Adverse reaction to antacids and antigastric secretion drugs.
SIDE EFFECTS:
Constipation.
PRECAUTIONS:
Before you use this medicine,
Do not use the medicine if:
Liver Disease
Avoid chalk in water retention in liver disease.
Renal Failure
Consider dose reduction in renal failure to avoid possibility of toxicity,
increased sensitivity and side effects.
Pregnancy
Drugs can have harmful effects on the fetus at any stage of pregnancy.
Experience with many drugs is limited. CHALK should only be used if expected
benefit outweighs possible risk.
PHARMACOLOGIC ACTIONS:
Antacid Effect.
FORMULATION NOTES:
Chalk is practically insoluble in water and is an undiffusable solid which requires a
suspending agent. Tragacanth powder is used in this formulation. The concentrated
cinnamon water is a flavoring agent and the syrup increase the viscosity as well as
acting as a sweetener. Chloroform water is the preservative.
METHOD OF PREPARATION:
The chalk and tracaganth should be weighed and lightly mixed in a mortar and
pestle. Add the syrup and mix to make a paste. The double strength chloroform
water should be gradually added, with mixing, followed by the concentrated
cinnamon water. The mixture should be rinsed into a previously tared 100ml amber
medicine bottle and made up to the volume with water. Shake the suspension well
and seal with a child resistant closure. Polish and label the bottle and give a 5ml
medicine spoon with the medicine

SHELF LIFE AND STORAGE:

Store in a cool, dry place. It is freshly prepared, therefore a shelf life of 1 week is
applicable.
ADVICE AND LABELLING:
Shake well before use. Advice on the importance of fluid replacement using oral
rehydration sachets should be given if necessary.
REFERENCE:
http://216.122.144.54/cgi-bin/drugcgic/INGR?136876289+0#CONTRAIND
GROUP 5
PH3Y2-2

PHM 325
MS. ORTEGA