bladder (a) The detrusor pressure rises only minimally (b) Proprioceptive impulses pass via the pudendal nerves (c) The first desire to void occurs at about 100 ml capacity (d) There may be voluntary pelvic floor contractions to maintain continence (e) An abnormally high detrusor pressure may be caused by interstitial cystitis T;F;F;T;T;
The pelvic floor
(a) has two distinct layers of support (b) is commonly disrupted by childbirth (c) gains the majority of its support from the transverse perineal muscles (d) consists of both fascial and muscular supporting structures (e) receives nerve supply from both the pudendal nerve and the pelvic plexus F; T; F; T; T;
Of the drugs used in the treatment of bladder
symptoms (a) Oxybutinin acts by an antimuscarinic action and a direct relaxant effect on the smooth muscle (b) Oxybutinin may have a dilitarious effect on cognitive function in the elderly (c) Tolterodine is more effective than Oxybutinin in controlling frequency of micturition (d) Imipramine is effective in the treatment of nocturnal enuresis in children (e) Desmopressin (DDAVP) can be used for treating nocturnal frequency and enuresis in adults T; T; F; T; T;
Oral anti-cholinergic treatment used
currently (a) is highly selective for bladder smooth muscle (b) increases bladder capacity (c) includes the drug baclofen (d) reduces leakage due to genuine stress incontinence (e) should not be used in patients with glaucoma F; T; F; F; T;
With regards to the somatic storage
reflex a) Its mediated in the Pontine micturition center. b) Higher centers have no role. c) NA and serotonin are inhibitory in the Onufs nucleus. d) Aids in stress continence mechanisms. e) Duloxetine acts as a adrenergic receptor agonist. F; F; F; T; F;