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IBRO - TIFR Neuroscience Symposium - PROGRAM

Tuesday - February 3, 2015

Venue: Faculty Lounge

Global Advocacy in APRC Region

Global Advocacy in APRC Region

9.00

Opening remarks by Keiji Tanaka (Chair, APRC)

9.10

Global Advocacy activities in IBRO (Sten Grillner)

10.00

Situations of neuroscience funding and research in individual countries 1

 

Japan (Tadashi Isa)

 

Korea (Yoo - Hun Suh)

 

China and Hongkong (Y.S. Chan)

 

Taiwan (Ding - I Yang)

12.00

Lunch Break

13.00

Situations of neuroscience funding and research in individual countries 2

 

Malaysia (Pike - see Cheah)

 

Singapore (S. Thameem Dheen)

 

Australia (John Rostas )

 

India (Upinder S. Bhalla)

 

Sri Lanka (Ranil De Silva)

 

Iran (Saeed Semnanian)

16.30

Coffee Break

17.00

Discussion on possible collaboration of global advocacy in APRC region

18. 00

Indian D ance P rogram - Kathak by students of the Beej School Venue: Homi Bhabha Auditorium Foyer

18. 30

Departure from A’ Block Reception for Banquet Dinner

19.00

Banquet Dinner at Konkan Café, Vivanta by Taj President

Wednesday - February 4, 2015

Venue : AG66

IBRO - TIFR Neuroscience Symposium

9.00

Opening remarks by Keiji Tanaka (Chair, APRC)

9.10

Plenary lecture: ‘The Computational Logics of Network in Motion – from Microcircuits to Selection of Behaviour’ by Sten Grillner

10.00

Lecture 1: ‘What D oes O ur V isual S ystem Know about the World?’ by S.P. Arun

10.35

Lecture 2 : Developmental Plasticity of Vestibular Circuits Regulates the Behavioral Outcome of Spatial Coding’ by Ying- Shing Chan

11.10

Coffee Break

11.30

Lecture 3: Functional Division among Prefrontal Areas of Macaque Monkeys’ by Keiji Tanaka

12.05

Lecture 4: Pathogenesis and T herapy for Alzheimer’s D isease (AD) and Parkinson’s D isease (PD)’ by Yoo - Hun Suh

12.40

Lecture 5 : Large- scaled Network Reorganization during Recovery from Partial Spinal Cord Injury’ by Tadashi Isa

13.15

Lunch Break

 

Lecture 6 : Early Adverse Experience and the Development of Psychopathology’ by

14.15

Vidita A. Vaidya Lecture 6 : ‘Ischaemia- Induced Neuronal Cell Death is Mediated by Molecular Targeting of CaMKII Phosphorylated at T253’ by JAP Rostas

14.50

Lecture 7 : Controlling flow of synaptic vesicles in neurons’ by Sandhya Koushika

15.25

Lecture 8 : ‘Ischaemia- Induced Neuronal Cell Death is Mediated by Molecular Targeting of CaMKII Phosphorylated at T253’ by JAP Rostas

16.00

Colloquium: Molecular- motor transport in cells: what is the importance of motor number, and how might this be regulated?’ by Steven Gross

17.00

High Tea

 

Indian Music Program - Pritam Bhattacharjee , Indian Classical vocalist from

18.00

Mewati Gharana. Venue: Homi Bhabha Auditorium Foyer

20.00

Banquet Dinner at TIFR Almond Groove

Why the Brain? - why advocacy?
Why the Brain?
- why advocacy?

Sten Grillner IBRO

The HUMAN BRAIN is the challenge of the 21st century

It is an electrochemical machine that enables us to think, perceive, act and remember that consists of:

100 000 000 000 nervecells 10 000 000 000 000 synapses (contact points) nervecells form functional modules/networks that subserve different functions Energy efficient – runs on 30 – 60 watts Diseases of the nervous system causes 35% of the costs for healthcare in North-America and Europe

Sten Grillner INTERNATIONAL BRAIN RESEARCH ORGANIZATION

Sten Grillner

INTERNATIONAL BRAIN RESEARCH ORGANIZATION

IBRO Organiza9on Founded in 1961, IBRO is governed by an Execu9ve CommiIee and a Governing

IBRO Organiza9on

IBRO Organiza9on Founded in 1961, IBRO is governed by an Execu9ve CommiIee and a Governing Council.

Founded in 1961, IBRO is governed by an Execu9ve CommiIee and a Governing Council.

IBRO Mission •   develop, support, coordinate and promote scienti2ic research in all 2ields concerning

IBRO Mission

develop, support, coordinate and promote scienti2ic research in all 2ields concerning the brain Promote neuroscience through interna0onal collabora0on and global interchange of scien0fic informa0on provide for and assist in educa0on and dissemina0on of informa0on rela0ng to neuroscience research

IBRO Membership

Corporate Members: 70 Neuroscience society or commi:ee, IBRO na0onal chapter, research council or similar

- e.g., Argen0nian Society for Research in Neurosciences, Chilean Neuroscience Society Academic Members: 12 Na0onal academies of science or similar

- e.g. La0n American Academy of Sciences (Mexico), Venezuelan Society of Physiological Sciences

IBRO Organiza9on

Secretariat in Paris Execu0ve Director Stephanie de la Rochefoucauld

Execu9ve CommiIee Chair: Sten Grillner (Secretary-General) Pierre MagistreP (President ) Quen0n Pi:man (Treasurer) Chairs of the 6 Regional Commi:ees Co-opted Members

Governing Council Chair: Pierre MagistreP (president) Representa0ves of Member Affiliated Organiza0ons Directors of Programmes & Chair of the World Congress Commi:ee Members of the Execu0ve Commi:ee

IBRO REGIONS

IBRO REGIONS

IBRO REGIONS

IBRO Regional CommiIees & Chairs

AFRICA: Pierre Luabeya (Democra0c Republic of Congo) ASIAN/PACIFIC: Keiji Tanaka (Japan) LATIN AMERICA: Dora Fix Ventura (Brazil) PAN EUROPEAN: Juan Lerma (Spain) USA/CANADA: Sharon Juliano (USA)

MIDDLE EAST/NORTHERN AFRICA (Sub-region):

Omar El-Agnef (UAE)

Global Advocacy CommiIee coordinated by IBRO

Global Advocacy CommiIee formed by SfN, FENS, IBRO, DANA, ISN, Japanese NS, Australian NS At the na9onal level only the Na9onal socie9es can act. For each region an advocacy workshop GAC plans to provide seed-money to the different global regions of IBRO

Global Advocacy Ini9a9ve 2014-15: Kinshasa, Buenos Aires, Mumbai

Global Advocacy Ini9a9ve

Global Advocacy Ini9a9ve 2014-15: Kinshasa, Buenos Aires, Mumbai

2014-15: Kinshasa, Buenos Aires, Mumbai

Neuroscience and society?

The goal must be to inform at all levels of society Legislators Funding organisa9ons Lay public solid informa9on on important items delivered by the best available scien9sts – credibility. No Hype….

Public funding Cancer and Brain Research

Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted
Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted
Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted
Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted
Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted
Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted
Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted
Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted
Public funding Cancer and Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted

Costs for Cancer and Diseases of the Brain

Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of
Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of
Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of
Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of
Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of
Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of
Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of
Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of
Brain Research Costs for Cancer and Diseases of the Brain Disability Adjusted Life Years Diseases of

Disability Adjusted Life Years

and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%
and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%
and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%
and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%
and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%
and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%
and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%
and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%
and Diseases of the Brain Disability Adjusted Life Years Diseases of the nervous system cause 35%

Diseases of the nervous system cause 35% of the costs for healthcare in North-America and Europe.

The BRAIN in focus for a great number of disciplines

The BRAIN in focus for a great number of disciplines Psychiatry Neurology Psychology Linguistics Geriatrics Cognitive

Psychiatry

Neurology

Psychology

Linguistics

Geriatrics

Cognitive and Systems mmNeuroscience Neurophysiology Molecular biology Pharmacology

The Brain not only in disease

How to maintain a healthy brain throughout life

Physical ac9vity, no smoking, diet

Understanding brain func9on from gene to behaviour–

understanding ourselves understanding animal kingdom – ethology

Learning and memory - the importance of brain func9on for

educa9on

Develop pharmaceu9cal industry – drugs considering degenera9ve diseases and psychiatric condi9ons Robo9cs, computers, informa9on processing

Basic science – “the unexpected usefulness” -- transistors, CCD cameras, MRI, penicillin, DOPA therapy against Parkinson´s…… Clinical care versus investment in science

care versus polio virus – vaccine

Translatory from basic mechanisms – to therapy – all clinical disciplines

a great challenge for current neuroscience the interface between the cellular level and global brain func@on -

between the cellular level and global brain func@on - ? Behaviour is produced by networks/microcircuits of
between the cellular level and global brain func@on - ? Behaviour is produced by networks/microcircuits of
?
?

Behaviour is produced by networks/microcircuits of interacting nerve cells

gene/molecule - cell - synapse - network – behaviour - cognition

How to support??

major breakthroughs are due to individual scien0sts - through dedicated work and crea0ve recombina0ons

Project grants Program grants – several inves0gators with complementary exper0se addressing the same problem

Plaaorm building important eg the Human Genome project, Allen Brain ins0tute, Flagship projects…INCF

Priori0es

US success acer the 2 nd world-war – funding but also effec0ve peer review scholarly selec0on of grants Problem-oriented rather than purely

descrip0ve

Breakthroughs to be preferred, but it ocen comes from systema0c incremental research towards solving a problem

Different Brain initiatives

EU flagship - Human Brain Project The Obama initiative NIH, NSF, DARPA Japanese initiative - marmoset Chinese initiative – on the way Australian initiative – on the way?

Current challenge

Excessive accumula0on of neuroscience data at all levels of analyses

- Difficulty to integrate and fundamentally understand

- Extending from genes to cogni0on and diseases Fragmenta0on and subspecialisa0on – many subdisciplines with very different methodology Many dynamic complex interac0ve processes Neuroinforma0cs important aid

GAC - Grants

For specific ac0ons Prin0ng of advocacy material Strategy workshops, analyses of specific situa0on with GAC grants in a given country etc Organize advocacy ac0ons – legislators , media etc € 5000? Prefer not for BAW Not for transla0ng

What do we like to achieve??

Awareness of possible strategies for advocacy for different groups Which organiza0ons are ac0ve, role of APRC Knowledge of strategies, materials developed by SfN, FENS or DANA Experience from other socie0es Views of different funding organiza0ons

Join forces between basic and clinical neuroscience, and brain-inspired technologies to argue for all the different aspects of neuroscience

9 th IBRO World Congress 2015

7-11 July, Rio de Janeiro, Brazil

9 t h IBRO World Congress 2015 7-11 July, Rio de Janeiro, Brazil IBRO2015.org

IBRO2015.org

IBRO World Congresses

1. Lausanne, Switzerland (1982)

2. Budapest, Hungary (1987)

3. Montréal, Canada (1991)

4. Kyoto, Japan (1995)

5. Jerusalem, Israel (1999)

6. Prague, Czech Republic (2003)

7. Melbourne, Australia (2007)

8. Florence, Italy (2011)

IBRO fellowships

Travel grants to mee0ngs, Short lab visits Post doc fellowships Return home fellowships

IBRO Schools

IBRO Schools To strengthen research training in each region 100 Schools from 2008-2014

To strengthen research training in each region

IBRO Schools To strengthen research training in each region 100 Schools from 2008-2014

100 Schools from 2008-2014

IBRO-FENS Cajal Advanced Training Programme Champalimaud Centre and Bordeaux Neurocampus

IBRO-FENS Cajal Advanced Training Programme

IBRO-FENS Cajal Advanced Training Programme Champalimaud Centre and Bordeaux Neurocampus
IBRO-FENS Cajal Advanced Training Programme Champalimaud Centre and Bordeaux Neurocampus

Champalimaud Centre and Bordeaux Neurocampus

Neuroscience Journal

Neuroscience Journal Official journal of IBRO, 28 issues per year by Elsevier www.journals.elsevier.com /neuroscience

Official journal of IBRO, 28 issues per year by Elsevier www.journals.elsevier.com /neuroscience

IBRO- Kemali Founda9on

IBRO- Kemali Founda9on

IBRO- Kemali Founda9on IBRO- Kemali Interna9onal Prize Research in the Field of Basic and Clinical

IBRO- Kemali Founda9on

IBRO- Kemali Founda9on IBRO- Kemali Interna9onal Prize Research in the Field of Basic and Clinical Neuroscience

IBRO- Kemali Interna9onal Prize Research in the Field of Basic and Clinical Neuroscience

THANK YOU

THANK YOU

IBRO Secretariat 255 rue Saint- Honoré 75001 Paris, France ibrocentral@gmail.com www.ibro.info

IBRO Secretariat 255 rue Saint-Honoré 75001 Paris, France ibrocentral@gmail.com www.ibro.info

The Brain and society?

The goal must be to inform at all levels of society

Legislators Funding organisations Lay public

solid information on important items delivered by the best available scientists – credibility. No Hype….

The HUMAN BRAIN is the challenge of the 21st century

It is an electrochemical machine that enables us to think, perceive, act and remember that consists of:

100 000 000 000 nervecells 10 000 000 000 000 synapses (contact points) nervecells form functional modules/networks that subserve different functions Energy efficient – runs on 30 – 60 watts Diseases of the nervous system causes 35% of the costs for healthcare in North-America and Europe

A large number of subdisciplines deal with brain func9on with widely different techniques

Psychiatry Neurology Psychology Linguis9cs Systems Neuroscience Pharmacology Neurophysiology Molecular biology

Disease mechanisms Cogni9on Emo9ons Memory and learning Motor co-ordina9on Networks Nerve cells & synapses Genes

Data bases thus need to extend from genes to behaviour and disease

Advocacy of Neuroscience in Japan

Chief Vice President, Japan Neuroscience Society Professor, National Institute for Physiological Sciences

Tadashi Isa

The current situation of neuro-psychiatric disorder

is very serious in Japan

1.

2.

3.

The biggest factor that harms the QOL of the Japanese nation is neuro -psychiatric disorder.

1/40 of the Japanese nation is currently under treatment of neuro-psychiatric disorder ‘this ratio will further increase in future).

The number of people with dimentia is estimated to be 4.6 million

(, which will increase in future because of longevity, while the total population of Japan, currently 120 million, will decrease).

4.

Economical loss by dimentia is estimated to be 1,000,000 million yen/year.

Furthermore, the Japanese people’s average life span is very long, but the number of children is decreasing (male: 80.21 (world no.4), female: 86.61 (world no.1)). Currently (in 2015), 25 % of the total population is over 65.

But drug development for neuro-psychiatric disorder is very difficult, presumably

because of the complexity of the target organ, brain.

We may need different strategies from that for cardiovascular disease or liver

dysfunction (drug delivery, animal model, physiological measure…).

For this, we need to know more about the brain.

Topics

1.

Funding system (s) in Japan Different Ministries fund neuroscience.

MEXT+JSPS

KAKENHI Grant (Bottom-up)

MEXT Flagship (top-down) project (Brain Science Committee)

SRPBS, MINDS

JST

ERATO, CREST, PRESTO, ERATO

Other Ministries (MHLW, MITI, MIC)

2.

Japan Neuroscience Society----community of neuroscientists in Japan

3.

Japanese Union of Neuroscience Societies

4.

Activity for advocacy

Briefing in the Committee of LDP

Master-plan

5.

Good side and bad side.

Abbreviations;

MEXT:

MHLW: Ministry of Health, Labour and Welfare

Ministry of Education, Culture, Sports, Science and Technology

MITI:

Ministry of International Trade and Industry

MIC:

Ministry of Internal Affairs and Communications

JSPS:

Japan Society for Promotion of Sciences (Agency related to MEXT)

JST:

Japan Science and Technology Agency (Agency related to MEXT)

Funding system(s) in Japan

Different Ministries fund neuroscience.

Strategic

(top-down)

Idea-driven

(bottom-up)

Developing Communication technology Overcoming neuro-psychiatric diseases Basic Application MIC “Innovative
Developing
Communication
technology
Overcoming
neuro-psychiatric diseases
Basic
Application
MIC “Innovative researches utilizing brain mechanisms”
(FY2011-2014, FY2011; 845 million yen)
Application of BMI to
Communication technology
MEXT “Strategic researches
of molecular imaging”
(FY2014; 250 million yen)
MITI “Early diagnosis of AD by integrating
brain imaging, clinics and IT”
(FY2014; 370 million yen)
MLHW ”Development of Biomarkers and imaging
Technology for depression and schizophrenia”
(FY2014; 400 million yen)
MHLW “Preclinical AD research”
(FY2014; 600 million yen)
Development of strategies
for diagnosis,
prevention and therapies
MEXT “Strategic research programs for brain sciences (SRPBS)”
MEXT “Brain Mapping by Integrated Neurotechnologies for Disease Studies(Brain/MINDS)”
Elucidating the mechanism
(FY 2015; totally 5,837 million yen)
of neuro-psychiatric diseases
JST CREST “neural circuit analysis”
(FY 2009-2016; 19 teams supported for 5 years, 0.5-1 million yen each)
JST CREST “Diagnosis and therapies of neuro-psychiatric diseases based on molecular pathology”
(FY2007-2014; 14teams supported for 5 years, totally 2.5-5 million yen for each)
JST PRESTO “Development and function of neural networks”
(FY 2009-2014; supporting 43 young scientists for 3-5 years; totally 50-100 million yen for each)
JST PRESTO “Decoding and controlling brain information”
(FY 2009-2014; supporting 37 young scientists for 3-5 years; totally 50-100 million yen for each)
MEXT & JSPS “Grant-in-Aid for Scientific researches (KAKENHI)”
Individual grants; Specially promoted research (no upper limit, 5 years), Type S (totally 200 million yean/5 years)
– Young B (totally 5 million yen/2-3 years)
Group grants (Scientific Researches in Innovative Areas); currently totally 19 neuroscience-related groups
(/117 groups from all the scientific fields) are funded (5 years for each, 300 million yean for each group)

Strategic research programs for Brain Sciences (SRPBS)

FY

2008

2009

2010

2011

2012

by MEXT

2013

2014

2015

2016

2017

Contribution to the Society Topic A (Group leader; M. Kawato (ATR)) “Development of BMI” Topic
Contribution to the Society
Topic A (Group
leader; M.
Kawato (ATR))
“Development of BMI”
Topic B (individual)
Topic B
(individual)
“Development of BMI”
“BMI”
Topic C (Group
leader; T. Isa (NIPS))
“Development of creative
animal model”
(genetic manipulation of primate brain)
Topic D (Group leader; M. Kano (Tokyo))
“Development of
social brain marker”
Topic E (Group leader; H.Mizusawa(Tokyo MD))
“Neural
functions for life-long health”
Topic F (Group leaders; S. Yamawaki,
N.Ozaki,
M. Takeda)“Elucidating neural mechanism
of neuro-
psychiatric disease and developing therapies”
Topic G (Group leader; K.Kaibuchi (Nagoya))
“Information infrastructure
of neuroscience”
BMI
technologies “Restoration
of impaired
body and mental
functions by BMI technologies”
Development of primate model
“Development
and distribution of TG
marmosets”

Totally 2,630 million yen

Brain Mapping by Integrated Neurotechnologies for Disease Studies

Brain Mapping by Integrated Neurotechnologies for Disease Studies http://brainminds.jp/en/ RIKEN BSI

http://brainminds.jp/en/

Brain Mapping by Integrated Neurotechnologies for Disease Studies http://brainminds.jp/en/ RIKEN BSI
Brain Mapping by Integrated Neurotechnologies for Disease Studies http://brainminds.jp/en/ RIKEN BSI
RIKEN BSI
RIKEN BSI
Brain Mapping by Integrated Neurotechnologies for Disease Studies http://brainminds.jp/en/ RIKEN BSI

How is the decision formed

on the top-down strategic projects?

MEXT, Minister

formed on the top-down strategic projects? MEXT , Minister Brain Science Committee (neuroscientists (both basic and

Brain Science Committee (neuroscientists (both basic and clinical), member from pharmaceutical company, journalist, liberal arts)

from pharmaceutical company, journalist, liberal arts) Science Council of Japan Master Plan + working groups Union
from pharmaceutical company, journalist, liberal arts) Science Council of Japan Master Plan + working groups Union

Science Council

of Japan

Master Plan

liberal arts) Science Council of Japan Master Plan + working groups Union of Brain Science Associations

+ working groups

arts) Science Council of Japan Master Plan + working groups Union of Brain Science Associations in

Union of Brain Science Associations in Japan

Neuroscience community

Unique community activity

Unique community activity One of the KAKENHI grant “Scientific Researches of Innovative Areas” More than 700

One of the KAKENHI grant “Scientific Researches of Innovative Areas”

More than 700 neuroscientists participate

1. Support system (5 items and 13 support centers)

(brain bank, behavioral analysis platform, molecular profiling

large-scaled neural recording technologies, developing animal models etc.)

Upon approval of applications, supports are available.

2. Organizing group meetings twice/year.

Research progress report, poster sessions, discussing on future proposals etc.

Budget; 360 million yen/year

The Japan Neuroscience Society

The Japan Neuroscience Society Headed by Keiji Tanaka as the president ----community of neuroscientists in Japan

Headed by Keiji Tanaka as the president

----community of neuroscientists in Japan

Founded in 1974 by 70 members.

Current number of members; 6000

Annual Meetings

About 2000 titles

of presentations About 3500-4000

participants

All in English Travel awardees are

invited (30-40 from

all over the world)

of presentations About 3500-4000 participants All in English Travel awardees are invited (30-40 from all over

Union of Brain Science Associations in Japan

--to form the “coherent voice” of neuroscientists--

-- to form the “coherent voice” of neuroscientists -- Total number of members; 80,000 (22 associations,

Total number of members; 80,000 (22 associations, in August 2014)

Japan Neuroscience Society (6,000)

Physiological Society of Japan (2,800)

The Japanese Association of Anatomists (2,500)

The Japanese Society for Neurochemistry

(1,400)

Japanese Neural Network Society

(800)

Japanese Society of Neurology (8,900)

Japanese Society of Child Neurology (3,800)

Japanese Society of Clinical Neurpphysiology (3,100)

Japan Society for Dementia Research (2,400)

Japanese Society of Psychiatry and Neurology (16,000)

Japanese Society of Sleep Research

(2,700)

Japanese Society Biological

Psychiatry(1,600)

Japanese Society of Neuropsychopharmacology (1,200)

Japanese Society of Clinical

Neurophychopharmacology (800)

Japan Society of Neurovegetative Research (1,200)

Japan Neuroendocrine Society (600)

Japanese Society for Neuroimmunology (580)

Neurology

(600) Japanese Society for Neuroimmunology (580) Neurology Rehabilitation Psychiatry Basic science Psychology

Rehabilitation

Psychiatry

Basic science

Psychology

Neurosurgery

Japanese Psychological Association

(7,400)

Japanese Association of Rehabilitation Medicine

(9,800)

Japan Neurosurgical Society (8,800)

Japanese Society for Neural Repair and

Rehabilitation (460)

Advocacy by the Union of Brain Science Associations

Advocacy by the Union of Brain Science Associations Proposal Hearing & briefing (about 1/year)
Advocacy by the Union of Brain Science Associations Proposal Hearing & briefing (about 1/year)
Advocacy by the Union of Brain Science Associations Proposal Hearing & briefing (about 1/year)

Proposal

Advocacy by the Union of Brain Science Associations Proposal Hearing & briefing (about 1/year)
Advocacy by the Union of Brain Science Associations Proposal Hearing & briefing (about 1/year)
Advocacy by the Union of Brain Science Associations Proposal Hearing & briefing (about 1/year)

Hearing & briefing (about 1/year)

Good side and bad side (& concerns)

1. Neuroscientist community is more and more integrated for making “coherent voice”. (ref. Union of Brain Science Associations, CBSA)

2. But the policy of the government is becoming more top-down, application-oriented.

3. From April 2015, a new organization (AMED; Japanese

version of NIH) will start and many of the MEXT

projects (most of the top-downs) will shift to it.

4. Share of Neuroscience papers from Japan is decreasing (!?)

Direction of FY 2015 Korean Government Investment in Life · Health Care Areas Increased sustainable
Direction of FY 2015 Korean Government Investment
in Life · Health Care Areas
Increased sustainable investment for public
health and new industries creation (Creativ
e Economy)
◈ Maximize R&D performance and efficiency
◈ Strengthen the efficient investment of core technol
ogies
-6-
FY 2015 Government R&D Budget (Unit :$ In millions) 2014 2015 Total 16,413 17,378 Basic
FY 2015 Government R&D Budget
(Unit :$ In millions)
2014
2015
Total
16,413
17,378
Basic science
Nanotechnology
2,293
2,028
Life Science & Healthcare R&D
Energy-Environment
2,339
2,350
$ 1,715
Aerospace-Life Science
4,348
4,870
Machinary-Manufacturing
1,560
1,589
-Process
(10% of
Total Budget)
Information-Electronics
2,400
2,336
Others
3,472
3,814
Source:- FY 2015 Budget by Ministry of Strategy and Finance
Top of the World Research Intensity : 4% of GDP
(Japan 3.4%, Germany & US, 2.8%)
Investment of Government Departments in Brain Research for Last 3 Years (Unit : $ In
Investment of Government Departments
in Brain Research for Last 3 Years
(Unit : $ In millions)
Year
2013
2014
2015
Departments
Total
81
100
120
Ministry of Science, ICT and Future Planning
(Government-funded research institution)
72
90
60.5
(45)
(60)
Ministry of Education
6
8
8
Ministry of Trade, Industry and Energy
1.5
4
4
Ministry of Health and Welfare
13
16
18
Investment of Government in Brain Research Areas for Last 3 Years (Unit: $ In millions)
Investment of Government in
Brain Research Areas for Last 3 Years
(Unit: $ In millions)
Year
2013
2014
2015
Areas
Total
81
100
120
Brain disorders
40
45
60
(50%)
Basic Neuroscience
15
17
18
(15%)
Neural information &
brain engineering
8
11
12
(10%)
Cognition
18
27
30
(25%)
* New Launched Projects :
Brain mapping project of Brain Development, PTSD project,
Pre-diagnostic project for AD prediction, and Internet and game detox project
FY 2015 KBRI Budget (Unit: $ In millions ) Year 2014 2015 Areas Total 66
FY 2015 KBRI Budget
(Unit: $ In millions )
Year
2014
2015
Areas
Total
66
70
□ Institute Operating Budget
7.3
10.6
§  Salaries
1.8
2.5
§  Recurring expenses
0.8
3.5
§  Intramural R&D
4.6
4.6
□ Special Budget
6.0
7.9
§  General expenses
6.0
7.9
- Computer network system
1.3
1.3
- Equipments
3.2
2.7
- Korea Brain Bank
0.7
0.7
- Animal Facility
0.7
3.1
Construction
52.7
51.5
Alzheimer’s Disease Death rate of AD only increases! Breast Prostate Heart Cancer Cancer Disease Stroke
Alzheimer’s Disease
Death rate of AD
only increases!
Breast
Prostate
Heart
Cancer
Cancer
Disease
Stroke
HIV
Alzheimer’s
Disease
Alzheimer’s Disease Global Economic Lo ss Economic Impact Research Fund $ 350 billion 2 times
Alzheimer’s Disease
Global Economic Lo
ss
Economic Impact
Research Fund
$ 350 billion
2 times higher than
cancer
1/12 of cancer
World
UK
UK
Korea
R&D Budget
300
250
200
Direct
Cost
Direct
Cost
150
Indirect
Cost
5.7%
Indirect
100
Cost
High income
Low income
Dementia Cancer heart
Dementia
50
Stroke
heart
Stroke
countries
countries
Cancer
0
Cancer
Vascular
Dimentia
Disorder
We have to try to increase government R&D Budget for Brain Research!
We have to try to increase
government R&D Budget
for Brain Research!
KBRI International Network
KBRI International Network
FY 2014 International Cooperative Brain Research of Korea $80,000 KOREA $80,000 $160,000 CNRS $30,000 A3
FY 2014 International Cooperative
Brain Research of Korea
$80,000
KOREA
$80,000
$160,000
CNRS
$30,000
A3 Foresight Program
$600,000
Securing Core Technology via Strengthening the Strategic Investment Cognition Neurooscience Neural Development &
Securing Core Technology via Strengthening the Strategic Investment
Cognition
Neurooscience
Neural Development & Regeneration
Neural Molecular & Cell Biology
Synaptic Plasticity & Excitation
Regulation of Neuron-Specific Function
Perception, Attention & Consciousness
Learning, Memory & Language
Emotion, Motivation & Decision-making
Social Cognition
Brain Disorders
Brain Engineering
Measurement & Modeling of Brain Structure
Brain-Machine Interface
Brain Function Enhancement Technology
Identification of Disease Mechanism
Drug Development for Brain Disorders
Patent(No.)
Articles(No.)
Year
Domestic
International
Over IF 20
Over IF 10
Total SCI
App
Issue
App
Issue
2010
112
32
41
21
1
9
719
2011
124
80
45
14
2
20
532
2012
96
59
36
12
7
127
610
2013
63
49
52
16
2
10
525
Korea Brain Research Institute(KBRI) We had the opening and completion ceremony o f the KBRI
Korea Brain Research Institute(KBRI)
We had the opening and completion ceremony o
f the KBRI building on Dec. 4 th , 2014.
Vision & Strategy of KBRI Top 7 World-leading Research Institute on Convergence Brain Science Basic
Vision & Strategy of KBRI
Top 7 World-leading Research Institute
on Convergence Brain Science
Basic Brain Science Research
(Neurobiology & Cognitive
Neuroscience) for Brain
Disease Solution
Medical Brain Science Research
(Brain Diseases Research:
Convergence Brain
Research:
Neurodegenerative and
Neurodevelopmental Disorders)
Brain Mapping
& Brain Engineering
Recruitment plan of KBRI PI at Assistant or Associate Professor levels should be at the
Recruitment plan of KBRI
PI at Assistant or Associate Professor levels should be at
the cutting edge of their field with an established record of
EXCELLENCE in brain research.
We will especially evaluate the record of research within
RECENT 5 YEARS (2009 ~ 2014).
VII. Working Environments of KBRI Competitive Salary National Pension, 4 Major Social Insuranc e
VII. Working Environments of KBRI
Competitive Salary
National Pension,
4 Major Social Insuranc
e
KIST Brain Science Institute Main Research Areas Center for Neuroscience •  Synaptic mechanisms of cognitive
KIST Brain Science Institute
Main Research Areas
Center for Neuroscience
•  Synaptic mechanisms of cognitive functions
•  Molecular mechanisms of cognitive functions
•  Research tool for acquiring, processing, and analyzing brai
n signals
Center for Functional Connectomics
•  Mapping of functional brain circuit by analyzing mouse mod
els at the synaptic and molecular level
•  Construction of the brain circuitry database by comparing h
ealthy and diseased brains
•  Developing therapeutic tools for various neurological disord
ers by identifying molecular mechanisms
Center for Neuro-Medicine
•  Synthesis and development of leading therapeutic candidat
es
•  Evaluation of the efficacy of lead compounds in animal mod
el
•  Development of neuro-imaging probes to diagnose brain di
seases
•  In silico drug design and assay development
•  Preclinical evaluation of lead compounds
IBS Institute for Basic Science Center for Synaptic Brain Dysfunctions •   Key Mecanisms of
IBS Institute for Basic Science
Center for Synaptic Brain Dysfunctions
•   Key Mecanisms of Synaptic Brain Dysfunctions
•   Neural Mechanism of Dicision making and Episodic momery
Center for Cognition and Sociality
•   Neural mechanism study on controlling consciousness and unconsciousness
•   Neural mechanism study on emotion and cognition
•   Neural mechanism study on sociality
•   Comprehensive analysis of protein-protein interaction networks
•   Development of molecular controllers manipulating signaling networks
Center for Neuroscience Imaging Research
•   Neurophysics, Neurochemistry, and Neural Engineering Group
•   Computational Neuroscience and Neural Imaging Data Analysis Group
•   Neurovascular Signaling Group
•   Primate Systems Neuroscience Group
•   Human Cognition Mapping Group
Neuroscience Research Institute (NRI) of Gachon University Research Team •   •   •  
Neuroscience Research Institute (NRI)
of Gachon University
Research Team
•  
PET-MRI Fusion
Stroke and Microvascular Imaging
Parkinson's and DBS
Hippocampus and Alzheimer's
fMRI and Cognitive Neuroscience
Animal and Molecular Imaging
RF and GR Coil Engineering
Cyclotron & Radiochemistry
Research Facility
• PET-MRI
• 7.0T MRI
• Cyclotron
• 1.5T MRI, 3.0T MRI & PET/CT
• HRRT PET
• Micro PET/CT
• Ultra Definition Display System
Brain Researchers of Korea •   Eight Korean neuroscientists got together during the 1982 meeting
Brain Researchers of Korea
Eight Korean neuroscientists got together during the 1982 meeting of SFN in Minneapolis, Minn
esota and agreed to have annual gatherings of Korean neuroscientists at subsequent meetings of the S
ociety
In 1988, at the Toronto, Canada meeting, bylaws were and the Association was formally founded
•  
There have been well over 230 Korean neuroscientists in attendance at recent annual dinner meet
ings
AKN ANNUAL MEETING REPORT 2014
Sponsors 2014
WASHINGTON, DC
Brain Researchers of Korea Neuroscience Annual Meeting at SFN – Top 5
Brain Researchers of Korea
Neuroscience Annual Meeting at SFN – Top 5
Thank you (yhsuh@kbri.re.kr)
Thank you
(yhsuh@kbri.re.kr)
Neuroscience Research and Funding in Hong Kong SAR / PR China
Neuroscience Research and
Funding in
Hong Kong SAR / PR China

Ying-Shing Chan

and Funding in Hong Kong SAR / PR China Ying- Shing Chan •   State Key

State Key Laboratory of Brain & Cognitive Sciences, University of Hong Kong

Past President, The Hong Kong Society of Neurosciences

  Past President, The Hong Kong Society of Neurosciences •   Standing Executive Committee Member, Chinese

Standing Executive Committee Member, Chinese Neuroscience Society

The Hong Kong Society of Neurosciences •   Standing Executive Committee Member, Chinese Neuroscience Society
B CHINA Shanghai Hong Kong SAR
B
CHINA
Shanghai
Hong Kong SAR

Neuroscience Research Ac5vi5es of universi5es in Hong Kong

- Neuroplas5city - Parkinsonism - Signal transduc5on in the nervous system - Forma5on of synapses
- Neuroplas5city
- Parkinsonism
- Signal transduc5on in the nervous system
- Forma5on of synapses during development
- Molecular mechanisms underlying neuronal survival
The Chinese University
of Hong Kong
- Structural biology of neuronal signaling complex
- Drug discovery for neurodegenera5ve diseases
Hong Kong University of
Science and Technology
- Auditory func5on
City University
- Visuo-auditory
of Hong Kong
interac5on
- Synap(c plas(city:
The University
of Hong Kong
Neurotransmi5ers / Neuromodulators
- Neural stem cell: Neurogenesis / iPSCs
- Memory & Alzheimer’s disease
- Neural regenera(on:
SCI, op(c nerve, peripheral nerve

Hong Kong Grants:

Hong Kong Research Grant Council (RGC)

Hong Kong Grants: Hong Kong Research Grant Council (RGC) General Research Fund [USD 150,000 for 3

General Research Fund [USD 150,000 for 3 years] Funded projects / year: 200 (for “Biology & Medicine”)

projects / year: 200 (for “Biology & Medicine”) Collabora5ve Research Fund [USD 500,000 – 1,000,000 for

Collabora5ve Research Fund [USD 500,000 – 1,000,000 for 3 years] Funded projects / year: 15

Neuroscience

21 projects

Areas of Excellence [USD 4M for 5 years]

Funded projects / round: 3

Theme-based Research Scheme [USD 5M – 10M for 5 years]

(a)Promo5ng good health

Funded projects / round: 3

Understanding Disease Mechanisms to Improving Health Stem Cells and Regenera5ve Medicine

(b) Developing a sustainable environment

Hong Kong Grants:

Hong Kong Research Grant Council (RGC)

Joint Research Schemes

Kong Research Grant Council (RGC) Joint Research Schemes Na5onal Natural Science Founda5on of China / RGC
Kong Research Grant Council (RGC) Joint Research Schemes Na5onal Natural Science Founda5on of China / RGC

Na5onal Natural Science Founda5on of China / RGC Joint Research Scheme

[USD 100,000 – 200,000 for 4 years] Funded projects / year: 20

100,000 – 200,000 for 4 years] Funded projects / year: 20 Agence Na5onale de la Recherch
100,000 – 200,000 for 4 years] Funded projects / year: 20 Agence Na5onale de la Recherch

Agence Na5onale de la Recherch / RGC Joint Research Scheme

[USD 200,000 – 300,000 for 4 years] Funded projects / year: 5

ScoPsh Funding Council / RGC Joint Research Scheme

[USD 20,000 for 1 year]

Hong Kong Grants:

Food and Health Bureau, HK Government

- Health and Medical Research Fund (HMRF) [USD 120,000 for 2 years]

Funded projects / year: 100

1) Infec5ous Diseases / Health Services 2) Advanced Medical Research - Paediatrics , Clinical Gene5cs, etc.

Neuroscience

Industrial & Technology Fund, HK Government

[USD 120,000 – 1M / year]

S.K. Yee Medical Founda5on Grants

1)Establishment of medical services for the poor and sick and the provision of equipment for such services.

2)Provision of funding to promote biomedical research. [USD 600,000 for 3 years]

The Croucher Founda5on

1)

Postdoctoral Research Fellowships - local & overseas.

[USD 50,000 / year]

2)

Clinical Assistant Professorships [USD 100,000 / yr salary + USD 70,000 seed funding]

The Hong Kong Society of Neurosciences

Founded in 1979 Current President: Wing-Ho YUNG A corporate member of:

President: Wing-Ho YUNG •   A corporate member of: - Interna5onal Brain Research Organiza5on ( IBRO

- Interna5onal Brain Research Organiza5on (IBRO )

- Federa5on of Asian-Oceanian Socie5es of Neurosciences (FAONS)

- Asia Pacific Society of Neurochemistry (APSN)

- hosted 4 th Congress

of Neurochemistry ( APSN ) - hosted 4 t h Congress Symposia in 2014 Conference :

Symposia in 2014 Conference:

- Hypoxia

- Learning and memory

- Molecular neuroscience

- Nerve regenera5on

- Neural stem cells

- Neurological disorders

- Neuropep5des

- Neurotrophic factors

- Synap5c plas5city

- Transla5onal neuroscience

Workshop on Biomedical Educa5on

Acupuncture Astrocyte Emo5onal disorders (Addic5on, Pain) Calcium signaling Cogni5on and fMRI Computa5onal
Acupuncture
Astrocyte
Emo5onal disorders (Addic5on, Pain)
Calcium signaling
Cogni5on and fMRI
Computa5onal neuroscience
Nerve injury & repair
Sensory circuitry & behavior
Social behavior: Molecular gene5cs & Circuitry
Parkinson disease
Qingdao U
Peking U
Tsinghua U
Inst Biophysics, CAS
Beijing Normal U
B
Degenera5on of basal ganglia
Drug addic5on
Ion channels and receptor
Learning and memory
Neural stem cells
Plas5city: Circuit & Behavior
Sensory systems: Vision, Pain
Qingdao
Cerebellum
Hypothalamus-brainstem interac5on
Nanjing U
Nanjing
Xi’an
Inst Neurosci, CAS
Fudan U
Shanghai Jiaotong U
2 nd Military Medical U
Shanghai
4 th Military Medical U
Hangzhou
Pain
Zhejiang U
Kunming
Inst Zoology, CAS
Astrocyte
Circuitry of psychiatric diseases
NMDA receptors
Guangzhou
Learning and memory
Sun Yat-sen U
Astrocyte
Hippocampal neurogenesis
Pain

PR China Grants:

Na5onal Science Founda5on of China

PR China Grants: Na5onal Science Founda5on of China Regular Research Projects General Research Projects [ USD

Regular Research Projects

General Research Projects [USD 0.1 M for 2-4 years] Funding rate: 20%

Key Projects

Other funding opportuni5es

[USD 0.4 M for 2-4 years] Funding rate: 20%

- Interna5onal Joint Research Fund

- Key / Major Research Plans

Talent Projects for Young Scien5sts

Young Scien5sts Fund

Excellent Young Scien5sts Fund [USD 0.7 M for 2-3 years]

Crea5ve Research Groups

[USD 0.04 M for 2-3 years] Funding rate: 24%

[USD >0.5 M ]

Funding rate: 11%

Research Environment Building Fund

Major Research Equipment & Facili5es [USD 0.5 - 25M ] Funded projects / year: 40

PR China Grants:

Ministry of Science & Technology

PR China Grants: Ministry of Science & Technology 973 Program Popula5on and Health 17% Projects [USD

973 Program

Popula5on and Health 17% Projects [USD 90 M]

Resource and Environment

9% Projects

Agriculture

9% Projects

Energy

8% Projects

Informa8on

11% Projects

Materials

8% Projects

Synthesis and Fron8er Science

4% Projects

863 Program

Biology

19% Projects [USD 35 M]

Resource and Environment

12% Projects

Energy

12% Projects

Informa8on

11% Projects

Synthesis

10% Projects

Agriculture

8% Projects

Marine

6% Projects

Materials

6% Projects

Source:

MST Annual Report of the State Programs of Science and Technology Development 2013

New Program (forthcoming)

Chinese NIH equivalent ??

The Chinese Neuroscience Society

Founded in 1995 Current President: Shumin DUAN

The Chinese Neuroscience Society •   Founded in 1995 •   Current President: Shumin DUAN
The Chinese Neuroscience Society •   Founded in 1995 •   Current President: Shumin DUAN
The Chinese Neuroscience Society •   Founded in 1995 •   Current President: Shumin DUAN
The Chinese Neuroscience Society •   Founded in 1995 •   Current President: Shumin DUAN
The Chinese Neuroscience Society •   Founded in 1995 •   Current President: Shumin DUAN

The Chinese Neuroscience Society

Founded in 1995 Current President: Shumin DUAN

Founded in 1995 •   Current President: Shumin DUAN Beijing / September 19 - 22, 2013
Founded in 1995 •   Current President: Shumin DUAN Beijing / September 19 - 22, 2013
Founded in 1995 •   Current President: Shumin DUAN Beijing / September 19 - 22, 2013

Beijing / September 19 - 22, 2013

Symposia:

- AD, PD

- Auditory circuits & func5on

- Au5sm; Depression; ForgePng

- Computa5onal neuroscience

- Glial cells

- Trafficking of receptors & ion channels

- Motor control & diseases

- Neural stem cell & 5ssue engineering

- Pathological pain

- PET / MRI in human brain

- Repair & regenera5on : CNS and PNS

Neuroscience Educa5on Workshop

- Iron metabolism & neurodegenera5ve disorders

The Chinese Neuroscience Society

Founded in 1995 Current President: Shumin DUAN

Founded in 1995 •   Current President: Shumin DUAN Chinese Neuroscience Society will host the 6
Founded in 1995 •   Current President: Shumin DUAN Chinese Neuroscience Society will host the 6

Chinese Neuroscience Society will host the 6 th FAONS Congress in Sept. 20-23, 2015

hnp://www.csn.org.cn/en/enindex.asp

in Sept. 20-23, 2015 hnp://www.csn.org.cn/en/enindex.asp •   Founded in 1996 FAONS Call for Symposia Submission

Founded in 1996

FAONS Call for Symposia Submission

Situa'ons of Neuroscience Funding and Research in Taiwan

Ding-I Yang, Ph.D. Secretary General- Taiwan Neuroscience Society Professor, Ins'tute of Brain Science, Na'onal Yang- Ming University, Taipei, Taiwan

TAIWAN: Where?

China TAIWAN Philippines
China
TAIWAN
Philippines

TAIWAN: basic informa'on

Republic of China Area:

36,193 km 2 Popula'on: 23.4 million Official language:

mandarin Capital: Taipei

Taipei
Taipei
language: mandarin •   Capital: Taipei Taipei Taipei 101 (508 m) Na'onal Palace Museum Jadeite
language: mandarin •   Capital: Taipei Taipei Taipei 101 (508 m) Na'onal Palace Museum Jadeite

Taipei 101 (508 m)

Na'onal Palace Museum Jadeite Cabbage IBRO-APRC Global Advocacy/2014-Feb-03 3
Na'onal Palace Museum
Jadeite Cabbage
IBRO-APRC Global Advocacy/2014-Feb-03
3

Outline

1. Es'mated numbers of PIs and publica'ons in neuroscience and brain research since 2012 2. Major funding agencies in Taiwan 1. Ministry of Science and Technology (MOST) 2. Ministry of Educa'on (MOE) 3. Na'onal Health and Research Ins'tute (NHRI) 4. Private founda'ons 5. Hospitals 3. Funding situa'ons in the neuroscience- and brain-related research ins'tutes in Taiwan 4. Crises and challenges in current situa'ons for neuroscience research in Taiwan

1. Researchers in neuroscience and brain science

Facul'es in the research ins'tutes related to neuroscience and brain science: 11 ins'tutes, 82 facul'es in total. Facul'es in neuroscience/brain research who are in other ins'tu'ons like pharmacology, physiology, toxicology, biochemistry, molecular biology, cellular biology, and anatomy, etc. Taiwan Neuroscience Society: 158 regular members, 140 student members, 318 in total. Clinical neurologists who are ac've in research.

1. Publica'ons during 2012-2015

Total: 2690+850=3540

1000 Brain-related articles Neuron-related articles 800 600 400 200 0 * 2012 2013 2014 2015
1000
Brain-related articles
Neuron-related articles
800
600
400
200
0
*
2012
2013
2014
2015
Number of Published Articles

* Up to January 30 th , 2015 Searched from PubMed

2. Funding resources in Taiwan

1. Ministry of Science and Technology (MOST) 2. Ministry of Educa'on (MOE) 3. Na'onal Health and Research Ins'tute (NHRI) 4. Private founda'ons 5. Hospitals (especially those affiliated with medical schools)

2.1. Ministry of Science and Technology

MOST , formally the Na'onal Science Council (NSC), is the main government funding agency for research in Taiwan Department of Life Sciences in MOST is the division to which most of the researchers in neuroscience and brain science submit their grant proposals. The only funding opportunity specific for neuroscience research is “Projects for the Promo'on of Neuroscience Research” (2008-2017).

MOST: Projects for the Promo'on of Neuroscience Research-I

350 301 300 271 250 250 200 150 100 50 0 2012 2013 2014 (*10
350
301
300
271
250
250
200
150
100
50
0
2012
2013
2014
(*10 4 USD)
60 6/32 50 18.8% 40 30 14/69 20 20.3% 10 38/149 25.5% 0 2012 2013
60
6/32
50
18.8%
40
30
14/69
20
20.3%
10
38/149
25.5%
0
2012
2013
2014
(*10 4 USD/project)

38=30+8 (2 program projects) 14=11+3 (1 program project)

MOST: Projects in Neurology-II

350 293 300 257 244 250 200 150 100 50 0 2012 2013 2014 (*10
350
293
300
257
244
250
200
150
100
50
0
2012
2013
2014
(*10 4 USD)
7 45/107 42.1% 42/102 6 45/106 41.2% 42.5% 5 4 3 2 1 0 2012
7
45/107
42.1%
42/102
6
45/106
41.2%
42.5%
5
4
3
2
1
0
2012
2013
2014
(*10 4 USD/project)

45=41+4 (1 program project) 45=45+0 (No program project) 42=42+0 (No program project)

10

IBRO-APRC Global Advocacy/2014-Feb-03

MOST: Projects in Neurosurgery-III

190 200 184 168 150 100 50 0 2012 2013 2014 (*10 4 USD)
190
200
184
168
150
100
50
0
2012
2013
2014
(*10 4 USD)
8 25/59 28/66 42.4% 34/75 42.4% 6 45.3% 4 2 0 2012 2013 2014 (*10
8
25/59
28/66
42.4%
34/75
42.4%
6
45.3%
4
2
0
2012
2013
2014
(*10 4 USD/project)

No program project

MOST: Projects in Psychiatry-IV

250 293 244 257 200 150 100 50 0 2012 2013 2014 (*10 4 USD)
250
293
244
257
200
150
100
50
0
2012
2013
2014
(*10 4 USD)
7 35/85 35/84 41.2% 41.7% 6 38/91 5 41.8% 4 3 2 1 0 2012
7
35/85 35/84
41.2%
41.7%
6
38/91
5
41.8%
4
3
2
1
0
2012
2013
2014
(*10 4 USD/project)

No program project

12

IBRO-APRC Global Advocacy/2014-Feb-03

2014

2013

2012

MOST: I+II+III+VI

1200 984 1000 961 874 800 600 400 200 0 2012 2013 2014 (*10 4
1200
984
1000
961
874
800
600
400
200
0
2012
2013
2014
(*10 4 USD)
(*10 4 USD/project)

10

8

6

4

2

0

8.66 7.69 5.99
8.66
7.69
5.99

Neuroscience budget in MOST

The 2013 annual budget for MOST is approximately 42.26 billion NTD, corresponding to 1.41 billion USD. This figure represents around 0.291% of our GDP (gross domes'c product; 484.7 billion USD in 2013). The 9.84-million figure in 2013 represents 0.698% of the total MOST annual budget. This is underes'mated value as funding from other categories (such as biochemistry) is not included.

Budget for a Typical MOST Grant

This is a 3-year grant supported by MOST, the 1 st year budget is 43333 USD. The pie chart demonstrates the distribu'on of various costs for this project in USD. The “consumables and reagents” may also used to hire a technician, cos'ng approximately 17000 USD/ year.

Administrative cost: 4683Travel: 3333 Personnel: 12800 Consumables and reagents: 22517

Travel: 3333Administrative cost: 4683 Personnel: 12800 Consumables and reagents: 22517

Personnel: 12800Administrative cost: 4683 Travel: 3333 Consumables and reagents: 22517

Consumables and reagents: 22517Administrative cost: 4683 Travel: 3333 Personnel: 12800

7.69% 29.54% 10.81% 51.96%
7.69%
29.54%
10.81%
51.96%

2.2 Ministry of Educa'on:

the 5-Y/5-B Plan

5-Year/5-Billion NTD (1.6 billions USD)

Ø The first term (2006-2010): Aim for Top University and Research Center Plan Ø The second term (2011-2016): Aim for the Top University Plan

Brain/Neuroscience-related research: Na'onal Taiwan University (Neuroscience and cogni've science; I); Na'onal Yang-Ming University (Brain science; I and II); Taipei Medical University (Stroke Research Center; I); Na'onal Tsing-Hua University (Brain science; II) Brain Research Center in Na'onal Yang-Ming University each year received <1 million USD research funding, individual PI may receive 10000-20000 USD research

2.3-5. Other Funding Resources

3. Na'onal Health and Research Ins'tute (NHRI) 4. Private founda'ons

Ø Taiwan Founda'on for Rare Disorders Ø Yen Tjing Ling Medial Founda'on

5. Hospitals (especially those affiliated with medical schools)

Ø Department of Health in Taipei City Government Ø Cheng Hsin General Hospital Ø Taipei Veterans General Hospital

3. Funding situa'on in individual research ins'tute

Depending on the number of faculty, as well as their research performance, one ins'tute may receive approximately 44000-1380000 USD from MOST each year during 2012-now. Each PI may receive 27000-138000 USD for each project of 1-4 years. Funding from other resources are not included.

Na'onal Yang-Ming University Ins'tute of Brain Science

70 60 50 40 30 20 10 0 2012/2013 2013/2014 2014/2015 2015/2016 (*10 4 USD)
70
60
50
40
30
20
10
0
2012/2013
2013/2014
2014/2015
2015/2016
(*10 4 USD)

Faculty number: 9

6 5 4 3 2 1 0 2012/2013 2013/2014 2014/2015 2015/2016 (*10 4 USD/faculty)
6
5
4
3
2
1
0
2012/2013
2013/2014
2014/2015
2015/2016
(*10 4 USD/faculty)

4. Crises and Challenges

Less young men are willing to devote themselves into basic research, including neuroscience and brain science, which is in part due to the lack of opportuni'es for permanent job posi'ons in either academy or industry. Low birth rate leading to less undergraduate and graduate students Shortage in funding opportuni'es and resources. Basic research versus clinical applica'on.

Acknowledgements

Dr. Shaw-Jeng Tsai; Director, Department of Life Sciences, Ministry of Science and Technology, Taiwan Dr. Ching Cheng; Program Manager for “Promo'on of Neuroscience Research”, Department of Life Sciences, Minister of Science and Technology, Taiwan

International Brain Research Organization Tata Institute of Fundamental Research Bringing Neuroscience to the World
International Brain Research Organization
Tata Institute of Fundamental Research
Bringing Neuroscience to the World
(Deemed University)
APRC member society representative
(Malaysia)
Dr. Pike-See Cheah (Pixie)
Universiti Putra Malaysia
Chair (Basic Neuroscience Chapter – Malaysian Society of Neurosciences)
Vice president (Malaysian Society of Neurosciences)
Council member (Asia Pacific Society for Neurochemistry)
1
11
Universi(es in Malaysia
Universi(es in Malaysia
Universi(es in Malaysia Private Universi(es, Universi(es colleges, Malaysian campuses of foreign universi(es = 82
Universi(es in Malaysia Private Universi(es, Universi(es colleges, Malaysian campuses of foreign universi(es = 82

Private Universi(es, Universi(es colleges, Malaysian campuses of foreign universi(es

= 82

Public = 21 (APEX U = 1) (RU = 4)

Universi(es, Universi(es colleges, Malaysian campuses of foreign universi(es = 82 Public = 21 (APEX U =

2

The Neuroscience Research is recognised as one of the priority niche areas in some universities of Malaysia.

3
3
Situa(on of support and funding to brain science/neuroscience in Malaysia 4

Situa(on of support and funding to brain science/neuroscience in Malaysia

Research Funding in Malaysia
Research Funding in Malaysia
Research Funding in Malaysia “MP is a comprehensive blueprint prepared by the Economic Planning unit (EPU)

“MP is a comprehensive blueprint prepared by the Economic Planning unit (EPU) of the PM’s Department & the Finance Ministry of Malaysia”

prepared by the Economic Planning unit (EPU) of the PM’s Department & the Finance Ministry of
prepared by the Economic Planning unit (EPU) of the PM’s Department & the Finance Ministry of

5

Research Funding in Malaysia
Research Funding in Malaysia

“In year 2011, 10 th Malaysia Plan allocated RM 600 millions / US $ 170 millions as research grant for public ins(tu(ons of higher learning.”

- Educa(on and Higher Learning Minister II , Datuk Seri Idros Jusoh

for public ins(tu(ons of higher learning.” - Educa(on and Higher Learning Minister II , Datuk Seri

6

Tenth Malaysia Plan (MP10)
Tenth Malaysia Plan (MP10)

2011-2015

Tenth Malaysia Plan (MP10) 2011-2015 7
7
7
Tenth Malaysia Plan (MP10) 2011-2015
Tenth Malaysia Plan (MP10)
2011-2015

MOSTI – Ministry of Science, Technology & Innova(on

Tenth Malaysia Plan (MP10) 2011-2015 MOSTI – Ministry of Science, Technology & Innova(on 8

8

Research Funding in Malaysia ~US $148 ~US $75 ~US $287 ~US $89 ~US $434 ~US
Research Funding in Malaysia
~US $148
~US $75
~US $287
~US $89
~US $434
~US $163

“The por(on of research funding on NEUROSCIENCE

is NA” – MOSTI, Malaysia (data obtained on 30 th Nov. 2014)

9

Situa(on of support and funding to brain science/neuroscience in Malaysia (RU, APEX) 10

Situa(on of support and funding to brain science/neuroscience in Malaysia (RU, APEX)

Research Funding in Malaysia
Research Funding in Malaysia

“In 2011, a total RM20 million has been given to seven Centres of Excellence (CoEs) to spur them to achieve the status of Higher Ins(tu(on Centres of Excellence (HICoEs).

1. Ins(tute of Oceanography, UMT 2. Photonics Research Centre, UM 3. Environment and Development Ins(tute, UKM 4. The Malay World and Civilisa(on Ins(tute, UKM 5. Centre of Excellence for Malaysian Technical University Network (CoE MTUN) 6. Centre for Research in Nanotechnology and Catalysis, UM

7. Neuroscience Service and Research Centre, USM

11

Mission : P3Neuro aims to welcoming the Government's call to generate insightful and highly potential

Mission : P3Neuro aims to welcoming the Government's call to generate insightful and highly potential human resources for science

Vision : P3Neuro offers eight main excellence services to local, regional and international levels.

12

.
.
* Clinical Neuroscience
* Clinical Neuroscience
. * Clinical Neuroscience * Social Neuroscience * Fundamental Neuroscience * Neuroeducation (innovation) *
* Social Neuroscience
* Social Neuroscience
* Fundamental Neuroscience
* Fundamental Neuroscience
* Neuroeducation (innovation)
* Neuroeducation (innovation)
* Neuro-literatures, public research
* Neuro-literatures, public research
* Neuro-industry & community
* Neuro-industry & community
* Neuroinformatics, computering neuroscience
* Neuroinformatics,
computering neuroscience
* Neuro-aesthetics (music, media)
* Neuro-aesthetics (music, media)
* Neuroimaging
* Neuroimaging
* Cognitive Neuroscience
* Cognitive Neuroscience
* Biomedical Neuroengineering
* Biomedical
Neuroengineering
https://www.facebook.com/P3NeuroUSM
https://www.facebook.com/P3NeuroUSM

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. Large scale brain mapping
.
Large scale brain mapping
. Large scale brain mapping 14
. Large scale brain mapping 14
. Large scale brain mapping 14
Public Universi(es
Public Universi(es
Public Universi(es Neuroscience research program Brain & Neuroscience (BNS) Community of Research (CoRe) Neuroscience

Neuroscience research program

Brain & Neuroscience (BNS) Community of Research (CoRe)

Neuroscience Research

Institute (coming soon)

program Brain & Neuroscience (BNS) Community of Research (CoRe) Neuroscience Research Institute (coming soon) 15
program Brain & Neuroscience (BNS) Community of Research (CoRe) Neuroscience Research Institute (coming soon) 15
program Brain & Neuroscience (BNS) Community of Research (CoRe) Neuroscience Research Institute (coming soon) 15

15

Private Universi(es 16
Private Universi(es
16
Funding opportunity
Funding opportunity
Funding opportunity Funding body Grant name Neuroscience field (specify or not?) MOSTI MOE (Ministry of

Funding

body

Grant name

Neuroscience

field (specify or not?)

MOSTI

MOE (Ministry of Education)

E-science fund

YES

FRGS (Fundamental Research Grant Scheme)

ERGS (Exploratory Research Grant Scheme)

LRGS (Long-term Research Grant Scheme)

PRGS (Prototype Research Grant Scheme)

RU (Research University)

Various types

17

MOSTI Malaysia Ministry of Science, Technology & Innova(on
MOSTI Malaysia
Ministry of Science, Technology & Innova(on

Malaysian Research and Development Classifica(on System - 6 th Edi(on FOR (Field of Research)

Category

Group

Area

Division 1 Natural Sciences

Systems

Systems Neuroscience

Biology

Division 5 Medical and Health Sciences

Neurosciences

Auditory Neuroscience, Autonomic Nervous System, Cell Receptors , Cellular Nervous System, Central Nervous System, Cerebral Palsy, Cerebral Vascular Disorder, Degenerative Diseases, Epilepsy, Migraine, Molecular Characterization, Neuropsychiatry, Peripheral Nervous System, Psychogeriatrics Sensory Systems, Sleep Disorders, Trauma Inflammation (Including Mechanism of Tissue Damage; Head Injury) Other Neurosciences n.e.c.

Biomedical

Behavioural Neuroscience

Science

 

18

Funding opportunity Funding Grant name Neuroscience body field (specify or not?) MOSTI E-science fund YES
Funding opportunity
Funding
Grant name
Neuroscience
body
field (specify or not?)
MOSTI
E-science fund
YES
FRGS (Fundamental Research
Grant Scheme)
NO
MOE
(Ministry of
Education)
ERGS (Exploratory Research
Grant Scheme)
NO
LRGS (Long-term Research
Grant Scheme)
PRGS (Prototype Research
Grant Scheme)
RU (Research
University)
Various types
19
Funding opportunity
Funding opportunity
Funding opportunity 20
Funding opportunity Funding Grant name Neuroscience body field (specify or not?) MOSTI E-science fund YES
Funding opportunity
Funding
Grant name
Neuroscience
body
field (specify or not?)
MOSTI
E-science fund
YES
FRGS (Fundamental Research
Grant Scheme)
NO
MOE
(Ministry of
Education)
ERGS (Exploratory Research
Grant Scheme)
NO
LRGS (Long-term Research
Grant Scheme)
NO
PRGS (Prototype Research
Grant Scheme)
RU (Research
University)
Various types
21
Funding opportunity
Funding opportunity
22
22
Funding opportunity Funding Grant name Neuroscience body field (specify or not?) MOSTI E-science fund YES
Funding opportunity
Funding
Grant name
Neuroscience
body
field (specify or not?)
MOSTI
E-science fund
YES
FRGS (Fundamental Research
Grant Scheme)
NO
MOE
(Ministry of
Education)
ERGS (Exploratory Research
Grant Scheme)
NO
NO
LRGS (Long-term Research
Grant Scheme)
if applicable
PRGS (Prototype Research
Grant Scheme)
RU (Research
University)
Various types
23
Funding opportunity
Funding opportunity
Funding opportunity 24
24
24
Funding opportunity
Funding opportunity

NO local grants specially dedicate to the fields of fundamental neurosciences.

For MAJOR grant applica(on, there is ligle or no room for the neurosciences fields as we know exist in developed countries.

25
25
Efforts that the community has made in Malaysia for promo(on of funding to brain science/

Efforts that the community has made in Malaysia for promo(on of funding to brain science/ neuroscience (successful and unsuccessful results)

Funding from community
Funding from community

Limited funding from Malaysian community dedicated to the research of fundamental neurosciences (unlike cancer research) .

funding from Malaysian community dedicated to the research of fundamental neurosciences (unlike cancer research) . 27
funding from Malaysian community dedicated to the research of fundamental neurosciences (unlike cancer research) . 27
funding from Malaysian community dedicated to the research of fundamental neurosciences (unlike cancer research) . 27

27

funding from Malaysian community dedicated to the research of fundamental neurosciences (unlike cancer research) . 27
Efforts – for promo(on of funding to brain science/ neuroscience “ To gather together all

Efforts – for promo(on of funding to brain science/ neuroscience

– for promo(on of funding to brain science/ neuroscience “ To gather together all professionals and
– for promo(on of funding to brain science/ neuroscience “ To gather together all professionals and

To gather together all professionals and allied health professionals in related fields to encourage activities promoting greater interest in the ever-widening field of Neurosciences.www.neuro.org.my

field of Neurosciences. ” – www.neuro.org.my “ To foster fundamental and comparative scientific

To foster fundamental and comparative scientific research contributing to an understanding of the nervous system of higher brain functions, biological basis of behaviour and its

disorders hCp://www.med.monash.edu.my/research/priori(es/ brims/neuromalaysia-society

Efforts – for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node &

Efforts – for promo(on of funding to brain science/ neuroscience

– for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node & Collaborative
– for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node & Collaborative
– for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node & Collaborative
– for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node & Collaborative
– for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node & Collaborative
– for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node & Collaborative
– for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node & Collaborative
– for promo(on of funding to brain science/ neuroscience “ Malaysian Neuroinformatic Node & Collaborative

Malaysian Neuroinformatic Node & Collaborative Projects Workshop –

5-year roadmap of projects.Oct. 2014.

29

Support from government
Support from government
Support from government MyCEB (Malaysia Conven(on & Exhibi(on Bureau) A non-profit organiza(on established by the

MyCEB (Malaysia Conven(on & Exhibi(on Bureau) A non-profit organiza(on established by the Ministry of Tourism, Malaysia.

established by the Ministry of Tourism, Malaysia. 2016 13 t h Meeting of the APSN, Kuala

2016

13 th Meeting of the APSN, Kuala Lumpur , Malaysia.

250-300

30

13 th Meeting of APSN 2016 Kuala Lumpur, Malaysia 27 th -30 th August 2016
13 th Meeting of APSN 2016 Kuala Lumpur, Malaysia 27 th -30 th August 2016
13 th Meeting of APSN 2016
Kuala Lumpur, Malaysia
27 th -30 th August 2016
APSN Neuroscience School 2016,
Kuala Lumpur , Malaysia.
22 nd – 26 th August 2016
Supported by
Presented by
31
Support from government
Support from government
Support from government 32
Support from government 32
32
32
Ideas , for interna(onal coopera(on in advocacy of brain science/ neuroscience to policy makers and

Ideas , for interna(onal coopera(on in advocacy of brain science/ neuroscience to policy makers and public

Strategy : Malaysian researchers collaborate with overseas collaborators via a win-win collabora(on to work on

Strategy : Malaysian researchers collaborate with overseas collaborators via a win-win collabora(on to work on the compounds isolated from plants or other natural products in Malaysia to facilitate the iden(fica(on of novel drugs in trea(ng neurological disorders.

Strategy : Similar massive ini(a(ve like the Brain Research Through Advancing Innova(ve Neurotechnologies (BRAIN) in

Strategy : Similar massive ini(a(ve like the Brain Research Through Advancing Innova(ve Neurotechnologies (BRAIN) in United States.

massive ini(a(ve like the Brain Research Through Advancing Innova(ve Neurotechnologies (BRAIN) in United States. 35
Materials and / or thoughts that will help other par(cipants to think about promo(on of

Materials and / or thoughts that will help other par(cipants to think about promo(on of funding to brain science/neuroscience research and related interna(onal coopera(on

Bigger science funding is absolutely crucial – Malaysia’s funding for scientific research compared to the

Bigger science funding is absolutely crucial – Malaysia’s funding for scientific research compared to the country’s GDP is hugely imbalanced.

crucial – Malaysia’s funding for scientific research compared to the country’s GDP is hugely imbalanced. 37
Research and development expenditure (% of GDP, 2014)   Country % of GDP 1 South

Research and development expenditure (% of GDP, 2014)

 

Country

% of GDP

1

South Korea

3.60

2

Japan

3.40

3

United States

2.80

4

Singapore

2.70

5

Taiwan

2.40

6

Australia

2.30

7

China

2.00

8

New Zealand

1.27

9

India

0.90

12

Malaysia

0.80

Australia 2.30 7 China 2.00 8 New Zealand 1.27 9 India 0.90 12 Malaysia 0.80 38
Australia 2.30 7 China 2.00 8 New Zealand 1.27 9 India 0.90 12 Malaysia 0.80 38
Interdisciplinary Research
Interdisciplinary Research

To attract more attention of government and public to capitalize/invest on the brain, there is a need to create symbiotic development of neuroscience in business & marketing is a potential approach.

39
39
Brain in Business (B in B)
Brain in Business (B in B)

To promote an exotic union of science and the arts, focus on the economics of neuroscience integrated neuroscience:

v

Neuroeconomics

v

Neuromarketing

v

Neurogovernance

(by Ahmad, ZA., 2010)

neuroscience: v   Neuroeconomics v   Neuromarketing v   Neurogovernance (by Ahmad, ZA., 2010) 40

40

Does Neuroscience stand for a chance for the funding opportunity below? Effort of MOSTI ,
Does Neuroscience stand for a chance for the funding opportunity below? Effort of MOSTI ,

Does Neuroscience stand for a chance for the funding opportunity below?

Effort of MOSTI, Malaysia with regard to funding as well as other initiative :

v Additional allocation of RM 50 million (~US $13.8 million) for Strengthen Technology Commercialization Platform Programme v RM 100 million to fund high impact R,D & C programme

Do you agree ?
Do you agree ?

“The new brain THINKS. It processes rational data.”

“The middle brain FEELS. It processes emotions and gut feelings.”

“The old brain DECIDES. It takes into account the input from the other 2 brains, but the old brain is he actual trigger of decision.”

by Renvoise & Morin, Neuromarketing, 2007.

THANK you! 43 43
THANK you!