Jj Wy CHEM 2388 pac? Name NTALLe Hillevson 1.34) ) (ay Hiydrates are usually present in only small umounts ip equiliteium with the corresponding carbonyl compound but are important intermediates in reactions such as the following, in which an exchange of oxygen alams occurs in acetone HY nerdney eno —te no bey one =" ‘The exchange is detected by wsing water containing "O, an inotape ofthe mone abundant "'O, Propose a mechanisen for the observed exchange of oxygen atom berwoen the carbonyl group and water in the presence of zeid. — i a . at = a. > oh Ht = > . 3 (> sou 70H (en? Hao Ye 2, t Hb.) ig em Y i) wo flab (b) Briefly explain the fact that, although hydration of cyclahexanone is thermodynamically disfavored, addition of water to cyclopropanone goes essentially to compiction: i WU prpanare is extremety A ho = * otis A nity bund angics (ée trum Ha dened 109° Wite tae cen toony| ip, HIS Sin iS OVE greciiee, ITO of Cycle proj gaat Felioves a Hyple ERE at) (©) Chloral hydrate is prepared by dissolving trichloroacetaldehyde in water. A solution of ie (aie ‘chloral hydrate in ethanol is called “knckout drops” because of its sedative and hypnotic effects. Draw the structure of chloral hydrate, and briefly explain why the hydration equilibrium of trichloroacetaldehyde is more favored than that of acetaldehyde. hPL Th chbnwis on Nov GLeTALAL Aye ee | Will yttrelectiw eECHors aid make : caviouny | COV Kin ry pits diving glwils Ic .