Part 1

Experiment title is cream formulation

1- write a process flow diagram of a cream manufacturing process
2- identify and explain the critical operating parameters of the
process
3- show the likely effects if these parameters are not controlled
4- describe how a cream manufacturing process might be validated
5- describe three typical tests that a pharmaceutical company
would need to perform prior to release of a batch of a human or
veterinary to the market.
Part 2
Experiment title is granulation formulation
1- write a process flow diagram of a wet granulation manufacturing
process
2- explain the need for being able to accurately determine
granulation end-point in mixer granulations. Show how the
properties of pellets manufactured in centrifugal granulator are
dependent on the starting materials such as binder solution
concentration and powder, particle size.
3- Identify and provide an outline the critical operating parameters
from milling to final tablet compression stage.
4- Describe three tests that a pharmaceutical company would use
prior to release to the market of a batch of tablets for human or
veterinary use.
Part 3
Experiment title is formulation and analysis of a toothpaste
1- identify and explain the critical operating parameters of the
processs?
2- describe three typical tests that a pharmaceutical company
would need to perform prior to release of a batch of toothpaste
to the market ?
3- what is the principle of operation of the fluoride electrode ?
4- what is the maximum pH at which this electrode can be used
satisfactorily?
Part 4
Experiment title is phase solubility analysis of glycine-alanine mistures
1- explain the difference between the solubility of a
nonelectrolyte and the solubility product of a slightly soluble
salt .

part 5
Experiment title is formulation and analysis of a calcium antagonist
microemulsion
1- account for the suitability of the techniques used to stabilize
emulsions
2- discuss the suitability of the parabens as preservations in
pharmaceutical emulsions.

Part 6
Experiment title is determination of copper in a supplement
1- account for the causes of copper deficiency as caused by
molybdenum

part 7
Experiment title is a comparison of the dissolution rates of nonsteroidal anti-inflammatory drugs
1- compare dissolution apparatus I and II suggesting why the
latter is more prevalent.
2- Suggest s strategy for measuring the dissolution rate of
lipophilic drug. Are there disadvantages to the approach
you suggest?
3- Describe what is meant by the term IVIVC in
biopharmaceutics?