therefore be exercised when considering sedation for patients
with a history of epilepsy. Fits can also occur in patients who lose consciousness for any other reason, especially those who faint and who are not immediately placed in a supine position. Acute chest pain Acute chest pain is usually caused by stable angina but the possibility of an acute coronary syndrome (unstable angina or myocardial infarction) should always be considered. Stable angina results from myocardial ischaemia caused by narrowing of the coronary arteries. The demands of the heart increase during exercise, stress or hypertension and it is these situations which are most likely to precipitate an angina attack. Patients with dental anxiety undergoing sedation are more at risk. The features of an angina attack are a severe retrosternal pain radiating down the left arm and a regular pulse. Sublingual glyceryl trinitrate spray (0.4mg), should be administered, the airway should be maintained and oxygen given. If there is no relief in three minutes, the possibility of unstable angina or myocardial infarction should be considered. Unstable angina is caused by fissuring of atheromatous plaques and subsequent platelet accumulation in a coronary artery. This results in varying degrees of occlusion of the affected artery. In myocardial infarction there is complete occlusion of a coronary artery, leading to sudden ischaemia and irreversible damage to part of the heart muscle. In myocardial infarction the patient will have severe crushing, retrosternal chest pain, which will not be relieved by use of glyceryl trinitrate. They will be pale and cyanosed, breathless and may vomit. The pulse will be weak and irregular. The patient should be allowed to find the most comfortable position to minimise the pain and this will usually be in the seated position. Patients should not be reclined unless they lose consciousness, since this increases the venous return and hence the cardiac output, thereby making more demands on the oxygen-starved myocardium. Nitrous oxide 50% with oxygen 50% (if available) should be administered to relieve pain and anxiety. Soluble aspirin (300mg) should be given orally and the emergency services should be summoned. The patient must be closely monitored for any deterioration, particularly cardiac arrest, in which case cardiopulmonary resuscitation should be initiated. Asthma Asthma is a very common condition which varies considerably in severity. An acute asthma attack may be precipitated by
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