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Adrenergic agonists

A.N.S pharmacology decided into drugs acting on


1- sympathetic nervus system
2- parasympathetic nervus system

Drugs acting on sympathetic nervus system


Devided into
1- Drugs which mimic the action of S.N.S
(sympathomimic drugs or adrenergic drugs or
adrenergic agonists)
2- Drugs which decrease the action of S.N.S
(sympatholytic drugs or anti adrenergic drugs or
adrenergic antagonists)
Now, let us talk about neurophysiology.
S.N.S and P.N.S are opposing each other and they are
working automatically. Not under our control, they control
the viscera, metabolic functions, etc.
Acute increase in the stress level will activate the
S.N.S. but how is S.N.S will be activated??
The activity stated from the C.N.S. and to be
accurate it is regulated by the hypothalamus and to be
more accurate it is the posterolateral area of the
hypothalamus which is responsible for the activation of
S.N.S and the anteromedial area is responsible for the
activation of P.N.S
But how the hypothamalus knows that there is a stress to
increase the sympathetic activity?

Actually, in the C.N.S


there is a large area
which is concerned with
emotions and behaviors
and memory. This area
called the limbic system.
The limbic system is a
group of multiple areas in
the C.N.S.
So, any stressful condition
will reach the limbic
system and activate it

Sympathetic outflow comes out of the spinal cord from the


thoracic and lumbar region (T1 L2 or L3)