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a) Radicular Cyst
b) Dental Cyst
c) Odontogenic keratocyst
d) Dentigerous Cyst
Answer: Odontogenic keratocyst
Explanation:
Odontogenic keratocyst is developmental odontogenic cyst of epithelial origin.
The odontogenic keratocyst is known for its high recurrence rate, aggressive
behavior, and its occasional association with the nevoid basal cell carcinoma
syndrome.
92. A toddler has few drops of blood coming out of rectum. Probable diagnosis is
a) Juvenile rectal polyp
b) Adenoid polyposis coli
c) Rectal cancer
d) Piles
Answer: Juvenile rectal polyp
Explanation:
Juvenile polyps are most common type of childhood polyps occurring in up to 1 % of
preschool children.
They are solitary polyps found in the rectum which most commonly present with
rectal bleeding.
93. Barretts esophagus is diagnosed by
a) Squamous metaplasia
b) Intestinal metaplasia
c) Squamous dysplasia
d) Intestinal dysplasia
Answer: Intestinal metaplasia
Explanation:
Barretts esophagus is a serious complication of GERD (Gastro-esophageal reflux
disease). In Barretts esophagus, normal tissue lining the esophagus changes to
tissue that resembles the lining of the intestine.
Barrett esophagus is marked by the presence of columnar epithelia in the lower
esophagus, replacing the normal squamous cell epitheliuman example of
metaplasia. This metaplasia confers an increased risk of adeno-carcinoma.
The presence of goblet cells, called intestinal metaplasia, is necessary to make a
diagnosis of Barrett esophagus.
94. Most common mechanism of GERD
105. Which of the following anti-estrogen drug is used in estrogen receptor positive
breast cancer?
a) Tamoxifen
b) Clomiphene Citrate
c) Estrogen
d) Adriamycin
Answer: Tamoxifen
Explanation:
Tamoxifen is only effective in treating estrogen receptor positive breast cancers.
Tamoxifen belongs to class of drugs known as selective estrogen receptor
modulators.
Tamoxifen is used to treat patients with early stage breast cancer as well as those
with metastatic breast cancer.
106. Acalculus cholecystitis are caused by
a) DM
b) TPN
c) Leptospirosis
d) Estrogen therapy
Answer: a, b and c
Explanation:
Acalculous cholecystitis is a severe illness that is a complication of various other
medical or surgical conditions.
Causes of Acalculous cholecystitis
Severe trauma
Burn
Postpartum period
Total parental hyper-alimentation
Biliary sludge
DM
Leptospira, Salmonella or V. coli
107. Right sided colon Ca is associated with
a) Anemia
b) Bleeding P/R
c) Mass P/A
d) Alternate constipation and diarrhoea
e) Internal obstruction
Answer: a and c
Explanation:
a) Hypersplenism
b) Hereditary spherocytosis
c) I.T.P
d) G. 6PD deficiency
e) Portal hypertension
Answer: All
Explanation:
114. True about Barretts esophagus
a) Metaplasia
b) Peptic stricture
c) Paraesophageal hernia
d) Squamous carcinoma
Answer: a, b and c
Explanation:
Complication of Barretts esophagus:
Peptic ulcer in lower end of esophagus
Stricture
Dysplasia (Adenocarcinoma)
Perforation
Important points:
Intestinal metaplasia with goblet cells in the esophagus is diagnostic of Barrette
esophagus.
115. In Crohns disease all are seen except
a) Hyper-plastic polyps
b) Diverticulosis
c) Fissuring ulcer
d) Epitheloid granuloma
e) Crypt abscess
Answer: a and b
Explanation:
Pathological features of Crohns disease:
Aphthous ulcer
Crypt abscess
Non caseating type of Epitheloid granuloma
116. B/L breast Ca
a) Lobular Ca
b) Ductal Ca
c) Comedo Ca
d) Cysto-sarcoma phyllodes
e) Scirrhous carcinoma
Answer: Lobular Ca
Explanation:
Invasive lobular Ca is frequently multifocal, multi-centric and bilateral.
117. Contraindication of enteral nutrition
a) Intestinal obstruction
b) Acute pancreatitis
c) Severe diarrhoea
d) IBD
e) Intestinal fistula
Answer: a, b, c and e
Explanation:
Contraindication of enteral nutrition:
Small bowel obstruction or ileus
Severe diarrhoea
Proximal small intestinal fistula
Severe pancreatitis
118. True about MEN II-b (Sipple syndrome)
a) Pheochromocytoma
b) Hyperparathyroidism
c) Muco-cutaneous neuromas
d) Medullary Ca of thyroid
Answer: a, c and d
Explanation:
MEN II-b (Sipple syndrome):
Medullary Ca of thyroid
Muco-cutaneous neuromas
Pheochromocytoma
Marfanoid features
119. Indications of surgery in pulmonary TB
a) Suspicion of malignancy
b) Cavitary lesion with Aspergilloma
c) Massive hemoptysis
d) All
Answer: All
Explanation:
a) Flush ligation
b) Stripping of great saphenous vein
c) Incompetent perforator ligation
d) Short saphenous ligation
Answer: a, c and d
Explanation:
Trendelenburg operation:
Flush ligation
Incompetent perforator ligation
Short saphenous ligation
Important point:
Trendelenburg operation is done for varicose vein which involve ligation of
saphenous vein.
126. Accidental finding of incidentaloma (Adrenal mass) is detected on USG.
Following is/are to be ruled out
a) Cushings disease
b) Metastasis
c) Adrenal adenoma
d) Carcinoma
e) Adrenal hyperplasia
Answer: All
Explanation:
Adrenal incidentaloma:
Aldosterone producing adenoma- 1 %
Metastatic carcinoma- 2 %
Adreno-cortical carcinoma- 5 %
Pheochromocytoma- 5 %
Pre-clinical Cushings- 5 %
Presumed non-functional adenoma- 82 %
127. A patient was presented with strangulated hernia, next line of management
a) Operate immediately
b) I.V. fluids
c) CT Scan
d) USG
e) X- ray abdomen
Answer: a and b
Explanation:
The diagnosis of strangulated hernia is made on clinical ground.
Vigorous resuscitation with intra-venous fluids, nasogastric aspiration and antibiotic
administration
Emergency or immediate operation
128. A/E used to detect Ca prostate
a) PSA
b) MRI
c) CT scan
d) DSA
e) TRUS
Answer: b, c and d
Explanation:
Investigation of Ca prostrate:
Digital rectal examination
TRUS (Trans-rectal USG)
Prostatic biopsy by TRUS or TURP
PSA
Important points:
CT scan is rarely accurate for staging and not routinely recommended.
Like CT, MRI is incapable of accurately differentiating intra-prostatic lesions.
DSA (Digital subtraction angiography)
129. Childs criteria includes
a) Encephalopathy
b) SGOT/SGPT
c) Ascites
d) Creatinine
e) Albumin
Answer: a, c and e
Explanation:
Revised Childs classification of clinical severity of cirrhosis: Criteria
Nutritional status
Ascites
Serum albumin
Serum bilirubin
Prothrombin time
Hepatic encephalopathy
130. Catheterization of bladder done in
a) Ca prostate
b) Post operative retention
c) Pre operative before taking the patient for appendicitis
d) Stricture
e) Rupture
Answer: a and b
Explanation:
Catheterization of bladder is done in Ca prostate, post operative retention and
major and lengthy operation.
Antihistaminics, antihypertensive, anti-cholinergic and antidepressant can induce
retention of urine.
131. True about thyroid Ca
a) Follicular Ca have worse prognosis than papillary Ca
b) Papillary Ca spreads by hematogenous route more frequently than follicular Ca
c) Papillary Ca has increased mortality than follicular Ca
d) Follicular Ca is more bilateral than papillary Ca
e) Follicular Ca has more male incidence than papillary Ca
Answer: a and e
Explanation:
Follicular Ca:
Male incidence- 35 %
Lymph node metastasis- 13 %
Blood vessel invasion- 60 %
Recurrence rate- 29 %
Overall mortality rate- 24 %
Papillary Ca:
Male incidence- 22 %
Lymph node metastasis- 35 %
Blood vessel invasion- 40 %
Recurrence rate- 19 %
Overall mortality rate- 11 %
Important points:
Thyroid tumor associated with MEN II: Medullary ca
Thyroid tumor with best prognosis: Papillary Ca
Thyroid tumor with worst prognosis: Anaplastic Ca
Thyroid tumor occurring in long standing goiter: Follicular Ca
Thyroid tumor occurring in Thyroglossal cyst: Papillary Ca
Thyroid tumor occurring in Cowden syndrome: Papillary Ca
132. True about solitary thyroid nodule
a) THR- antibody
b) Lined by columnar epithelium
c) Diffuse hyperplasia of thyroid
d) Common in female
e) Thyroidectomy done
Answer: d and e
Explanation:
Solitary thyroid nodule is about four times more common in women than men.
Solitary thyroid nodule is removed surgically to exclude malignancy.
133. Good prognostic markers in breast Ca
a) ER (receptors) +ve
b) Progesterone (receptors) +ve
c) HER -2 /neu (receptors) +ve
d) CD44 receptor +ve
e) P53 gene +ve
Answer: a and b
Explanation:
Good prognostic markers in breast Ca:
ER (receptors) +ve
Progesterone (receptors) +ve
Worst prognostic markers in breast Ca:
HER -2 /neu (receptors) +ve
Mutated P53 gene
Presence of more micro-vessels
Non-diploid tumors
Tumor with poor nuclear grade
Cell cycle antigen PCNA/ki67
134. In the Rx of hydatid cyst, PAIR is contraindicated in
a) Lung/bone cyst
b) Size> 5cm
c) Not amenable to Rx with Albendazole
d) Multiple
e) Inaccessible location
Answer: a d, and e
Explanation:
Indications of PAIR (Puncture, aspiration, injection, re-aspiration):
Non-echoic lesion 5 cm
Cyst with daughter cysts
Multiple cysts if accessible to puncture
Infected cyst
Contra-indications of PAIR (Puncture, aspiration, injection, re-aspiration):
Inaccessible location
Multiple cysts not accessible to puncture
Cyst in spine, brain, bone, lung, heart
Anastrozole
Exemestane
Aminoglutethimide
Important points:
Tamoxifen is an antagonist of the estrogen receptor in breast tissue.
138. Screening increases life span in which of the following carcinoma
a) Breast
b) Colon
c) Prostate
d) Lung
Answer: a, b and c
Explanation:
Screening increases life span in the following carcinoma and screening techniques:
Breast- Self breast examination and mammography
Colon- Fecal occult blood, sigmoidoscopy and colonoscopy
Prostate- Digital rectal examination and PSA
Cervical cancer- Pap smear
139. Hemangioma of the rectum
a) Common tumour
b) Fatal hemorrhage seen
c) Ulcerative colitis like symptoms seen
d) All
Answer: b and c
Explanation:
Hemangioma of the rectum:
An uncommon tumor
Large tumor and sometime bleed profusely
Ulcerative colitis like symptoms in diffuse neoplasm or tumor location in upper part
of rectum and treated with selective angiography and embolization
Hemangioma of lower part of rectum is treated with local excision.
140. Gases used for Pneumo-peritoneum are
a) CO2
b) N2
c) O2
d) Room air
e) N2O
Answer: a, c, d and e
Explanation:
Treatment:
Curettage and Cauterization
Laser surgery
Cryotherapy
143. True about struma ovarii
a) Ectopic thyroid
b) Ectopic ovary
c) Malignancy
d) Benign lesion
e) Included in Teratoma
Answer: d and e
Explanation:
Struma ovarii is a rare ovarian tumor defined by the presence of thyroid tissue
comprising more than 50% of the overall mass.
It most commonly occurs as part of a Teratoma, but may occasionally be
encountered with serous or mucinous cystadenomas.
The vast majority of struma ovarii are benign; however, malignant disease is found
in a small percentage of cases.
144. T/t of malignant tracheo- oesophageal fistula includes
a) Expandable metal stent
b) Surgery with graft
c) Gastrostomy tube
d) Radiotherapy
e) Chemotherapy
Answer: a, b and c
Explanation:
Malignant tracheo- oesophageal fistula:
Expanding metal stent- Probably best treatment
Semi-rigid prosthetic tubing or Gastrostomy tube
Surgical bypass and esophageal exclusion
Important point:
It is sign of incurable esophageal carcinoma.
145. A pt on TPN develops deficiency of
a) Folic acid
b) Iron
c) Vitamin B-12
d) Copper
e) Fatty acids
Answer: All
Explanation:
Complication of TPN (Late 3 months onward):
Essential fatty acid deficiency
Vitamin deficiency
Zn, Iron, Copper, chromium and selenium deficiency
146. True about branchial cyst
a) Seen deep to lower 1/3 of sterno-cleidomastoid
b) Wall consists of lymphoid tissue
c) Filled with straw colored fluid with cholesterol crystals
d) None
Answer: b and c
Explanation:
Brachial cyst:
Brachial cysts are characteristically found anterior and deep to upper third of
sterno-cleidomastoid.
Second brachial remnants are the most common
Usually lined by squamous epithelium and shows layer of lymphoid tissue
Contain thick turbid full of cholesterol crystals
Treatment- Surgical excision
147. Structures not removed in radical neck dissection
a) X nerve
b) XI nerve
c) Tail of parotid
d) Parotid and post- auricular nerve
Answer: a and d (?)
Explanation:
Structures not removed in radical neck dissection:
Carotid artery
Brachial plexus
Phrenic nerve
Vagus nerve
Marginal mandibular branch of facial, lingual and glosso-pharyngeal nerves
Cervical sympathetic chain
Structures removed in classical radical neck dissection:
Cervical lymphatics and lymph nodes
Internal jugular vein
Accessory nerve
Sterno-cleidomastoid
Omohyoid
Tail of parotid
Submandibular gland
148. Variant of papillary carcinoma thyroid
a) Medullary
b) Warthins
c) Columnar
d) Insular
e) Diffuse sclerosing
Answer: c, d and e
Explanation:
Variants of papillary carcinoma thyroid:
Pure papillary
Follicular variant
Diffuse sclerosing
Tall cell variant
Columnar cells variant
Insular
Variants of follicular carcinoma thyroid:
Minimally invasive
Widely invasive
Hrthle cell carcinoma
Insular
149. Diagnosis of traumatic rupture of diaphragm is made by
a) Laparoscopy
b) Chest X ray
c) Diagnostic peritoneal lavage
d) None
Answer: a and b
Explanation:
Diagnosis of traumatic rupture of diaphragm:
Chest X-ray after placement of nasogastric tube
The most accurate evaluation is by VATS (Video assisted thoracoscopy) and
laparoscopy.
Contrast study of GI, CT scan and diagnostic peritoneal lavage all lacks positive or
negative predictable value.
150. True about breast carcinoma in men
a) Estrogen receptor positive
b) Associated with gynecomastia
c) Radiotherapy contraindicated due to close proximity to chest wall
d) None
Answer: a and b
Explanation:
Breast carcinoma in men:
Approximately 90 % of male breast cancers contain estrogen receptors.
Associated with gynecomastia and risk of cancer is much greater in men with
gynecomastia
Irradiation is the first step in treating localized metastasis.