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Medical Study

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Centre

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Session 2011-2016
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We the team of medical study centre session


2011-2016 have copmiled these pharma
mnemonics unit wise. We hope our effort of
mnemonics collection will help you all in proff.

ce

nt

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We want that this collection must be shared with


your friends and fellows .please give us your feed
back about this collection in our group and page

ALI Zeeshan(QAMC)
ATHAR ALI (QAMC)
Noreen FATIMA (FJMC)

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Regards: admin Panel

https://www.facebook.com/groups/Medical.study.ce
ntre/
http://atharali187.blogspot.com/

atharali187.blogspot.com

Pharmacology
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Mnemonics

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General pharma

atharali187.blogspot.com

1. Zero order kinetics drugs in high doses


APE

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Aspirin
Phenytoin
Ethanol

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2. P450 inhibitors
IQ SMACKD

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Isoniazid

ss

Quinolones

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Spironolactone

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Macrolides

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Ketoconazole

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Cimetidine

nt

Amiodarone

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Dapsone

atharali187.blogspot.com

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3. P450 inducers
GTQ CRABS
Grisofulvin
Tetracyclin

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Quinidine
Carbamazepine

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Rifampin

ss

Alcohol

se

Barbiturates

re

Sulfa drugs

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4. Enzymes Inhibitors

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"Vit. K Cannot Cause Enzyme Inhibition"


Valproate

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Ketaconazole

Cimetidine

Ciprofloxacin

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atharali187.blogspot.com

Erythromycin

INH

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5. ototoxicity causative agents


A+.B.C.D. "

Barbiturates

Cytotoxic drugs-Nitrogen mustard & cisplatin affect


Organ of corti (irreversible)
Diuretics-Ethacrynic acid, frusemide cause Ionic changes
(reversible)

ce

COMIC CASE '

nt

6. enzymes inhibitor

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Aminoglycosides* (Profound and irreverible hair cell


loss)

Cimetidine

Omeprazole

Metronidazole

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atharali187.blogspot.com

Chloramphenicol

Ciprofloxacin

Allopurinol

Sulphonamides

Erythromycin

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Isoniazid

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7. drugs metabolized by acetylation

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SHIP'

Sulfonamides including dapsone

Hydralazine

Isoniazid (INH)

Procainamide

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8. teratogenic drugs :major non-antibiotics


TAP CAP:

Thalidomide

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atharali187.blogspot.com

Androgens

Progestins

Corticosteroids

Aspirin & indomethacin

Phenytoin

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9. therapeutic index formula

'TILE':

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TI = LD50 / ED50

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10. drug with low therapeutic index

'The Queen Likes to Dig Low'


Theophylline

Quinine

Lithium

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atharali187.blogspot.com

Digoxin have

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11. G protein for receptors


"QISS & QIQ" (Kiss and Kick):

G-protein Q: alpha 1 receptor,

G-proteins I: alpha 2 receptor ,

G-proteins S: beta 1 receptor ,

G-protein S: beta 2 receptor

G-protein Q: M1 receptor,

G-protein I: M2 receptor,

G-protein Q: M3 receptor.

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G-proteins and their respective receptors in alphabetical order:

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&

12. oral drugs forming insoluble complexes


TIAPS '

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Read as Tie-ups.

atharali187.blogspot.com

Tetracycline with Iron compounds

Antacids/Phenytoin with Sucralfate

13. autoinduction
Drugs that induce their own metabolism

20

Auto,Car & Rickshaw

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Autoinduction -Carbamazepine & Rifampin

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14. orally ineffective or less effective drugs

Pencillin-G

Insulin

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"Dont put PINS inside the mouth!"

Neostigmine

Streptomycin

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15. non-competitive inhibitor drugs

atharali187.blogspot.com

A LIVE TIPS AD
A. acetazolamide

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Live. Lovastatin
t. theophylline
I. Indomethacin
P. Propyl thiouracil

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S. Sildenafil

A. Aspirin

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D. Disulfiram

nt

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PHC IS Primary
P-Procainamide
H-Hydralazine
C-Clonazepam
I-INH
S-Sulphonamides
P-Phenelzine

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16. drygs metabolised by Acetylation

atharali187.blogspot.com

17. zero order kinetic

11
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SWAT - Salicylate, Warfarin, Alcohol,


Theophylline
Police - Phenytoin
Team Tolbutamide
18. LIVER ENZYME INDUCERS

20

SB CCPR

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SULFAPYRAZONE
BARBITURATES
CHRONIC ALCOHOL
CARBAMEZEPINE
PHENYTOIN
RIFAMPICIN

atharali187.blogspot.com

19. Enzyme inducers


GPRS Cell Phone

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G-Griseofulvin
P-Phenyton
R-Rifampicin
S-Smoking
C-Carbamazepine
P-Phenobarbitone

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20. acetylation drugs

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DSHIP=DAPSONE,SULPHONAMIDE,HYDRALAZINE,INH,;;;PROC
AINAMIDE

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21. . Gi mediated receptors

nt

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Muscarinic
Alpha
Dopamine

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Type 2 receptor of

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MAD 2

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Act through GPCR with Gi as Gprotein

atharali187.blogspot.com

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beta c amp glue lubricates so many thyroids


Beta- beta agonists,
C-CRH,calcitonin,hCG,
a-alpha2 agonist, ACTH,ADH,
m-MSH,
p-PTH,
glue-glucagon,
Lubricates-LH,
somany-somatostatin,
Thyroid-TSH

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22. camp as second messenger

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23. TORSADES DE POINTES

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QUINIDINE
DISOPYRAMIDE
SOTOLOL
PROCAINAMIDE
ARSENIC OXIDE
AMIADARONE
AZOLES

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QUEEN IS SONALI, , PRIYANKA, ASIN, AMRITHA, or KAZOLE:

atharali187.blogspot.com

24. microsomal enzyme inhibitor

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PEACOCK VALA

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P: PHENYLBUTAZONE
E: ERYTHROMYCIN
A: ALLOPURINOL
C: CIPROFLOXACIN
O: OMEPRAZOLE
C: CIMETIDINE
K: KETOCONAZOLE
VALA: VAPROATE

atharali187.blogspot.com

25. Drugs with high hepatic extraction ratios


"I've pickl'd Pam" or "I pickled vamp" if you prefer.

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Imipramine
Verapamil
Etomidate

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Propofol
Isoniazid
Chlorpromazine
Ketamine
Lidocaine
Diltiazem

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se

Propranolol
Amitriptyline
Morphine

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Also might help to remember there are three induction agents propofol/ketamine/etomidate, four antiarrhythmics verapamil/diltiazem/propranolol/lidocaine and five nerve-y drugs amitriptyline/imipramine/chlorpromazine/morphine/isoniazid
(neurotoxic!)

atharali187.blogspot.com

26. competitive inhibition


Km is increased in Kompetitive inhibition

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27. hit n run drugs

20

ROGI R- RESERPINE
O-OMEPRAZOLE
G-GUANTHIDINE
I-INHIBITERS[MAO]

Chief Minister ADD CIA

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trichloroethanolChlorhydrate
Morphine 6-glucuronideMorphine

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28. EXAMPLES OF ACTIVE DRUG PRODUCING ACTIVE


METABOLITES

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AlloxanthineAllopurinol
oxazepamDiazepam
digoxinDigitoxin

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morphineCodeine
desipramineImipramine
NortriptylineAmitriptyline

atharali187.blogspot.com

29. EXAMPLES OF PRODRUG PRODUCING ACTIVE


METABOLITES

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LEADS
Levodopa dopamine
Enalapril enalaprilat

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Alphamethyldopa alphamethylnorepinephrine.
Dipivefrine epinephrine

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Sulindac sulfide metabolites

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Cindy Has A New Motor


C aptopril
H istamine
A drenaline
N icotinic acid
M ethyldopa

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30. DRUGS METABOLISED BY METHYLATION

atharali187.blogspot.com

Ans Pharma
1. beta 1 selectibe bloker

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A-BEAM
Acebutalol
Betaxolol
Esmolol

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Atenolol

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Metprolol

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2.uses of propranolol

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Angina

nt

Headach

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HATE THE PAST

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Tension

Essential trmors

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Tensional headach

atharali187.blogspot.com

Hyperthyroidism
Elevated B.P

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Phobia
Anxiety
Stress

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Traumatic stress

3.contraindication of propranolol

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ACID

se

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Asthma
COPD

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Diabetic mellitus

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Imbalance of electrolyte

4. adverse affects of beta blockers

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BBC Loses Viewera In Rawalpindi


Bradycardia

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Bronchospasm

atharali187.blogspot.com

Lipids (increased)
Vivid dreams

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Impotency
Reduced sensitivity to hypoglycemia

5. non selective beta blockers

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PANTOP

Prapranolol

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Alprenolol

se

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Nadolol
Timolol

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Oxprenolol

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Pindolol

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6. cardioselective beta blockers


CaN BEAM"

Celiprolol

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atharali187.blogspot.com

Nebivolol (most selective)

Bisoprolol, Betaxolol

Esmolol

Atenolol, Acebutolol

Metoprolol

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7. beta blockers with instrinsic sympathetic activity (ISA)

Pindolol, Penbutolol

Alprenolol

Acebutolol

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Celiprolol, Oxprenolol

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8. receptors of heart

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Think: They "COntain Partial Agonistic Activity"

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2 Beautiful hearts Marry 2 Be 1"


B2 receptor (adrenergic)
M2 receptor (cholinergic) and

B1 receptor (adrenergic)

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9. morphine vs amphetamine. Pupils in overdoses

atharali187.blogspot.com

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MorPHINE is Fine & AmPHETamine is Fat !"

Morphine overdose: pupils constricted (fine)

Amphetamine overdose: pupils dilated (fat)

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10. anticholinergic side effects

"Know the ABCD'S of anticholinergic side effects":


Anorexia

Blurry vision

Constipation/ Confusion

Dry Mouth

Sedation/ Stasis of urine

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11. antimuscrinic drugs and their action

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Inhibits Parasympathetic And Sweat ":


IIpratropium

Pirenzepine

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atharali187.blogspot.com

Atropine

Scopolamine

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12. edrophonium vs pyridostigmine in myasthenia gravis


eDrophonium is for Diagnosis

And pyRIDostigmine is to get RID of symptoms

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13. MOA of tacrine and edrophonium

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TEA ":

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Tacrine and Edrophonium attach only to Anionic site of


enzyme,Cholinesterase(ChE)

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( Organophosphates attach only to the estatrtic site of


Cholinesterase )

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14. reversible anticholinesterases

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Car PPENDoRi ": Read as "carpentry"

atharali187.blogspot.com

Physostigmine

Pyridostigmine

Edrophonium

Neostigmine

Donepezil

Rivastigmine

20

11
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Reversible Anticholiesterases belonging to Carbamates are

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15. Muscarinic effects

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SLUG BAM ":

Salivation/ Secretions/ Sweating

Lacrimation

Urination

Gastrointestinal upset

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Bradycardia/ Bronchoconstriction/ Bowel movement

Abdominal cramps/ Anorexia

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atharali187.blogspot.com

Miosis

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16. nicotinic affects


" MTWThF in rhythm "(days of week):
Mydriasis/ Muscle cramps

Tachycardia

Weakness

Twitching

hypertension/ hyperglycemia

Fasiculation

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17. cholinergic affects on bowl and bladder

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Call inergic/Cholinergic makes us attend natures call ! ":

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ie.,Evacuation of Bowel and Bladder

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18. organophosphates eefects ( Cholinergic)

atharali187.blogspot.com

"If you know these, you will be LESS DUMB Choline ":
Lacrimation

Excitation of nicotinic synapses

Salivation

Sweating

Diarrhea

Urination

Micturition/Miosis

Bronchoconstriction

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19. cholinergic agonists

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Esters: A-MCB

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ACh ,Methacholine ,Carbechol ,Bethanechol


Alkaloids: PMA

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:Pilocarpine, Arecoline, Muscarine

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20. autoreceptors

atharali187.blogspot.com

Au to receptors ":

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The' to' rhymes with 2.


So the Autoreceptors are Alpha 2 (for adrenergic pathway)
and M2 (for cholinergic pathway)

21. cholinergic receptor


MuGNiL":

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22. botulinus toxin action

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Muscarinic :G protein coupled


Nicotinic :Ligand gated ion channel

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Think: Botulinum toxin Bottles up Acetyl choline (ACh).

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It means, botulinum toxin blocks exocytic release of ACh


from the synaptic vesicles at the neuromuscular junction
leading to flaccid paralysis.

atharali187.blogspot.com

23. inhibiton of choline uptake during Ach synthesis

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H-I-C-Up "
Hemicholinium Inhibits Acetyl Choline Uptake

24. site of acetyl choline release

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"PreACh ":

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Acetyl Choline ( ACh ) is released from all Pre ganglionic


fibres of ANS

"LMNOP":
Lipid soluble

Miotic

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25. physostigmine vs neostigmine

Natural

Orally absorbed well

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atharali187.blogspot.com

Physostigmine

A goes with B":


Atropine used clinically to treat Bradycardia.

20

27. reserpine action

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26. atropine use : tachycardia or bradycardia

nt

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28. ipratropium action

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Reserpine depletes the Reserves of catecholamines [and


serotonin].

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Atropine is buried in the middle: iprAtropium, so it behaves


like Atropine.

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29. succinylcholine uses

atharali187.blogspot.com

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Succinylcholine gets Stuck to Ach receptor, then Sucks ions


in through open pore.
You Suck stuff in through a mouth-tube, and drug is used for
intubation.

30. depression causing drugs

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PROMS:
Propranolol
Reserpine
Oral contraceptives
Methyldopa
Steroids

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DINED:
Dopamine
Isoproterenol
Norepinephrine
Epinephrine
Dobutamine

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31. direct sympathomimetic catecholamine

atharali187.blogspot.com

20

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32. Morphine: side-effects MORPHINE:


Myosis
Out of it (sedation)
Respiratory depression
Pneumonia (aspiration)
Hypotension
Infrequency (constipation, urinary retention)
Nausea
Emesis

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33. Bromocriptine [for USA gang members] The CRYPTS are


an LA street gang that likes to smoke DOPE.
BromoCRYPTine is a DOPamine agonist.

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35.

nt

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34. Guanethidine: mechanism GuaNEthidine prevents NE


(norepinephrine) release.

atharali187.blogspot.com

11
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Parasympathetic vs. sympathetic neurotransmitters "No


sympathy for a Pair of Aces":
Norepinephren is secreted in by the Sympathetic nervous system
while Acetylcholine is secreted in the Parasympathetic nervous
system.

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Morphine: effects at mu receptor PEAR:


Physical dependence
Euphoria
Analgesia
Respiratory depression

20

36.

ss

37.

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38.

nt

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Prazocin usage Prazocin sounds like an acronym of "praszz


zour urine".
Therefore Prazocin used for urinary retention in BPH.

atharali187.blogspot.com

20

11
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Beta blockers with CYP2D6 polymorphic metabolism "I Met


Tim Carver, the metabolic polymorph":
The following beta blockers require dose adjustment due to CYP2D6
polymorphic
metabolism:
Metoprolol
Timolol
Carvedilol
(in patients with lower or higher than normal CYP2D6 activity)

39.

ss

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harry potter sees 2 BP and PIPE

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alpha blockers uses

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harry=hypertension
potter=pheochromocytoma
sees2= secondary shock
BP= benign hypertrophy of prostate
PIPE= penile impotence

atharali187.blogspot.com

40. Parasympathetic action

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11
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Parasympathetic action
@SLUDD + 3Ds
Salivation
Lacrimation
Urination (so Anticholinergics cause urinary retension)
Digestion
Defecation
3 important Decreases
Decrease in heart rate and contractility
Decrease in pupil size i.e. Miosis
Decrease in airway size (so anticholinergics given in COPD)

atharali187.blogspot.com

41. Physostigmine vs. neostigmine

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20

11
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@ LMNOP:
Lipid soluble
Miotic
Natural
Orally absorbed well
Physostigmine
Neostigmine, on the contrary, is:
Water soluble
Used in myesthenia gravis
Synthetic
Poor oral absorption

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MAP of ABC
M= muscarine
A= arecoline
P= pilocarpine
of
A= acetylcholine
B= bethanechol
C= carbachol

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42. cholinergic classification

atharali187.blogspot.com

43. reversible anticholinesterase


NEW GALLANT DON ED TAKES REVERSE SPY

20

11
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NEW= neostigmine
GALLANT= galantamine
DON= donepezil
ED= edrophonium
TAKES= tacrine
REVERSE= rivastigmine
SPY= pyhsiostigmine/ pyridostigmine

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( gallant means brave)

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44. alpha 1 agonists

nt

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M-methoxamine
M-midodrine
N-naphazoline
O-oxymetazoline
P-phneylephrine

re

M.MNOP

atharali187.blogspot.com

45. beta-1 selective blocker


NAME-ABC

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N-nebivolol
A-atenolol
M-metoprolol*
E-esmolol

20

A-acebutanolol**
B-betaxolol
C-celiprolol**

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*drug having membrane stabilising activity also.

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** drug having membrane stabilising as well as intrinsic


sympathomimic action

atharali187.blogspot.com

46 Cardioselective Beta Blockers

20

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New Beta Blockers Acting Exclusively At Myo Cardium


Nebivolol(most cardioselective)
Betaxolol
Bisoprolol
Atenolol
Esmolol
Acebutolol
Metoprolol
Celiprolol

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47. cholinergic crisi

se

DUMBELSS

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Diarrhoea
Urination
Miosis
Bronchospasm
Excitation cns and neuromuscular
Lacrimation
Sweating
Salivation

atharali187.blogspot.com

48. lipid insoluble b blocker


Not soluble a b c

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Nadolol
Sotalol
Atenolo acebutolol
Betaxolol bisoprolol
Celiprolol

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49. CARDIOSELECTIVE B BLOCKER

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ATENOLOL
METOPROLOL
ESMOLOL
BETAXOLOL
ACEBUTALOL

ameba

atharali187.blogspot.com

50. reversible Anticholinestrases

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ANTI- ANTICHOLINESTERASE
RaGING REVERSE,RIVASTIGMINE POLICE- PHYSIOSTAGMINE
TAKE -TACRINE
GREAT -GALANTAMINE

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DON DONEPEZIL

atharali187.blogspot.com

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HM HAT CM CD PAGE
H-Hypertension
M-Myoardial infarction
H-Hypertrophy obstructive cardiomyopathy
A-Angina pectoris
T-Thyrotoxicosis
C-Congestive Heart failure
M-Migraine
C-Cardiac arrythmias
D-Dissecting aortic aneurysm
P-Pheochromocytoma
A-Anxiety
G-Glaucoma
E-Essential tremors

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51. Uses of beta blockers

atharali187.blogspot.com

52. Effects of Beta blockers on Heart and Bloodvessels

20

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SORAB got CHF


S- Prolong Systole
O- Dec Oxygen consumption
R- Dec Refractory period of myocytes
A- Dec automaticity
B- Dec SBP nd DBP on Chr Administration
C- Dec Cardiac output, Cardiac work & total coronary blood flow
H- Dec Heart rate
F- Dec Force of contraction

53. Beta blockers contra in renal failure

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"ANS"

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Atenolol
Nadolol
Sotalol

nt

54. sympathomimetic hypertensives

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Many- Mephenteramine
People- Phenylephrine
Never- Noradrenaline
Marry- Methoxamine

atharali187.blogspot.com

55. zero order kinetics-ITS AWESOM


text WHATT are these drugs.

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W- warfarin
H- hydantoin
A- aspirin
T- tolbutamide
T- theophylline

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ADRENALIN USES
ABC HIL
A-ANAPHYLACTIC SHOCK
B-BRONCHOSPASM
C-CARDIAC ARREST
H-HEAMOSTATIC AGENT
I-INSULIN INHIBITION
L-LOCAL ANAESTHETIC

20

56. ADRENALIN

ce

57. AGONISTS OF DOPAMINE

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B-BROMOCRIPTINE
A-ANTICHOLINERGICS(CENTRAL)
L-LEVODOPA

atharali187.blogspot.com

CVS PHARMA
1. aspirin side affects

Asthma

Salicylism

Peptic ulcer / Premature closure of PDA

Intestinal blood loss

Reye's syndrome

Idiosyncracy

Noise (tinnitus)

se

ss

io

20

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6

"ASPIRIN"

2. hypertension management

re

"ABCD"

ACE inhibitors/Angiotensin receptor blockers

Beta blockers

Calcium channel blockers

Diuretics

ls
tu
dy

ce

nt

ed

ic
a

3. amiodarone : adverse affects

atharali187.blogspot.com

Plz Check PFT, LFT, TFT "


Plz- Photosensitivity, Pigmentation

Check for Corneal deposits

PFT- Pulmonary fibrosis

LFT- Liver damage (pseudoalcoholic liver injury)

TFT- Thyroid dysfunction

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4. antihypertensive : contraindicated in pregnancy

DARSAN '
Diuretics

Angiotensin I antagonists

Reserpine

Sodium nitroprusside

ACE inhibitors

Non selective blockers

ce

nt

re

se

ss

io

ls
tu
dy

5. antiarrythmic drugs: clases

ed

ic
a

" i' M BAC in rhythm ":

atharali187.blogspot.com

11
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6

I.Membrane stabilizing agents (Na channel blockers)


II.Beta blockers (Antiadrenergic agents)
III.Agents widening AP
IV.Calcium channel blockers

6. receptors of heart

M2 receptor (cholinergic) and

B1 receptor (adrenergic)

io

B2 receptor (adrenergic)

se

ss

20

"2 Beautiful hearts Marry 2 Be 1"

7. patent ductus arteriosus treatment

nt

re

Come IN and Close the Door":

ce

INdomethacin is used to Close the PDA.


8. ca ++ channel blocker:uses

ls
tu
dy

Ca++ MASH:

Cerebral vasospasm/ CHF

ed

ic
a

atharali187.blogspot.com

angina

Migraine

Atrial flutter, fibrillation

Supraventricular tachycardia

Hypertension

11
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6

ed

ic
a

ls
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ce

nt

re

se

ss

io

20

9. >Captopril(anACEinhibitor):sideeffectsCAPTOPRIL:
Cough
Angioedema/Agranulocystosis
Proteinuria/Potassiumexcess
Tastechanges
Orthostatichypotension
Pregnancycontraindication/Pancreatitis/Pressuredrop(firstdose
hypertension)
Renalfailure(andrenalarterystenosiscontraindication)/Rash
Indomethacininhibition
Leukopenia/Livertoxicity

atharali187.blogspot.com

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10.>Warfarin:metabolismSLOW:
Hasaslowonsetofaction.
AquicKVitaminKantagonist,though.
Smalllipidsolublemolecule
Liver:siteofaction
Oralrouteofadministration.
Warfarin

se

ss

io

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11.>Amiodarone:action,sideeffects6P's:
Prolongsactionpotentialduration
Photosensitivity
Pigmentationofskin
Peripheralneuropathy
Pulmonaryalveolitisandfibrosis
PeripheralconversionofT4toT3isinhibited>hypothyroidism

nt

re

12. >Clopidogrel:useCLOPIdogrelisadrugthatprevents
CLots,anOralPlateletInhibitor(OP

ed

ic
a

ls
tu
dy

ce

13.>Warfarin:action,monitoringWePT:
WarfarinworksontheextrinsicpathwayandismonitoredbyPT.

atharali187.blogspot.com

11
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14.Enoxaprin(prototypelowmolecularweightheparin):action,
monitoringEnoXaprinonlyactsonfactorXa.
MonitorXaconcentration,ratherthanAPTT.

20

14.>ThrombolyticagentsUSA:
Urokinase
Streptokinase
Alteplase(tPA)

ed

ic
a

ls
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ce

nt

re

se

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15. >Antiarrhythmics:classificationItoIVMBACollege
InorderofclassItoIV:
Membranestabilizers(classI)
Betablockers
Actionpotentialwideningagents
Calciumchannelblockers

atharali187.blogspot.com

20

11
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16.>HMGCoAreductaseinhibitors(statins):sideeffects,
contraindications,interactionsHMGCoA:
Sideeffects:
Hepatotoxicity
Myositis[akarhabdomyolysis]
Contraindications:
Girlduringpregnancy/Growingchildren
Interactions:
Coumarin/Cyclosporine

nt

re

se

ss

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17.>Antiarrhythmics:classIIImembersBIAS:
Bretylium
Ibutilide
Amiodarone
Sotalol

ed

ic
a

ls
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ce

18.>ACEI:contraindictionsPARK:
Pregnancy
Allergy
Renalarterystenosis
Kincrease(hyperkalemia)

atharali187.blogspot.com

se

ss

io

20

11
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19.>EndotrachialtubedeliverabledrugsONAVEL:
Oxygen
Naloxone
Atropine
Ventolin(albuterol)
Epinephrine
Lidocaine
Ifyoucan'tgetIVaccessestablished,andhavenecessityto
administerresuscitativemeds,rememberyouhavetheairwayand
cangivetheabovedrugs.
Drugdeliveryisenhancedifdilutedwith10ccNSandrapid
introducedforaeresolization.
Alternatively,bareboneversionisALE,asabove.

ce

21.Arrhythmias

nt

re

20.SVTCausesSNAP
Sinustachy,nodaltachy,afib,paroxysmalatrialtachy

ls
tu
dy

ARHYTHMIAL4PC
AtrialMyxoma

ed

ic
a

Rhheartdis

atharali187.blogspot.com

Hypertension
THyrotoxicosis

IHD,
Alcohol

20

Pneumonia/PE/Pericardialeff,cardiomyopathy

22. >AtrialFibrillation

ss

io

ARITHMATIC

se

Alcohol

re

Rhfever

ce

ls
tu
dy

Hypertension

nt

IHD
Thyrotoxicosis

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6

Mitralvalvedis

Mitralstenosis/MI/Myxoma
(atrial)

ed

ic
a

ASD

atharali187.blogspot.com

Toxins,
Idiopathic/Infectiveendocarditis

11
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6

Cardiomyopathy/Constrictivepericarditis

SympatheticactsonSodiumchannels(SS).

20

23.Sinoatrialnode:innervations

ss

io

ParasympatheticactsonPotassiumchannels(PS).

ed

ic
a

ls
tu
dy

ce

nt

re

se

24.>Supraventriculartachycardia:treatmentABCDE:
Adenosine
Betablocker
Calciumchannelantagonist
Digoxin
Excitation(vagalstimulation)

atharali187.blogspot.com

11
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6

ed

ic
a

ls
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ce

nt

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se

ss

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20

25.>Ventriculartachycardia:treatmentLAMB:
Lidocaine
Amiodarone
Mexiltene/Magnesium
Betablocker

atharali187.blogspot.com

ed

ic
a

ls
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nt

re

se

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26.>Sinusbradycardia:aetiology"SINUSBRADICARDIA"(sinus
bradycardia):
Sleep
Infections(myocarditis)
Neapthyroid(hypothyroid)
Unconsciousness(vasovagalsyncope)
Subnormaltemperatures(hypothermia)
Biliaryobstruction
RaisedCO2(hypercapnia)
Acidosis
Deficientbloodsugar(hypoglycemia)
Imbalanceofelectrolytes
Cushing'sreflex(raisedICP)
Aging
Rx(drugs,suchashighdoseatropine)
Deepanaesthesia
Ischemicheartdisease
Athletes

atharali187.blogspot.com

20

11
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6

27.>Atrialfibrillation:causesPIRATES:
Pulmonary:PE,COPD
Iatrogenic
Rheumaticheart:mirtralregurgitation
Atherosclerotic:MI,CAD
Thyroid:hyperthyroid
Endocarditis
Sicksinussyndrome

re

se

ss

io

28.>Atrialfibrillation:managementABCD:
Anticoagulate
Betablocktocontrolrate
Cardiovert
Digoxin

ed

ic
a

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ce

nt

29.>Atrialfibrillation:managementABCD:
Anticoagulate
Betablocktocontrolrate
Cardiovert
Digoxin

atharali187.blogspot.com

20

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30.>SinustachycardiaTACHFEVER:
Tamponade/Thyrotoxicosis
Anemia
CHF
Hypotension
Fever
Excrutiatingpain
Volumedepletion
Exercise
Rx(Theo,Dopa,Epi,etc)

ed

ic
a

ls
tu
dy

ce

nt

re

se

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31.Vfib/Vtachdrugsusedaccordingto
ACLS"EveryLittleBoyMustPray":
Epinephrine
Lidocaine
Bretylium
Magsulfate
Procainamide

atharali187.blogspot.com

ed

ic
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32.>Ventricularfibrillation:treatment"Shock,Shock,Shock,
EverybodyShock,LittleShock,BigShock,MommaShock,Poppa
Shock":
Shock=Defibrillate
Everybody=Epinephine
Little=Lidocaine
Big=Bretylium
Momma=MgSO4
Poppa=Pocainamide

atharali187.blogspot.com

re

se

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33. >Atrialfibrillation:causesofnewonsetTHEATRIALFIBS:
Thyroid
Hypothermia
Embolism(P.E.)
Alcohol
Trauma(cardiaccontusion)
Recentsurgery(postCABG)
Ischemia
Atrialenlargement
Loneoridiopathic
Fever,anemia,highoutputstates
Infarct
Badvalves(mitralstenosis)
Stimulants(cocaine,theo,amphet,caffeine)

ed

ic
a

ls
tu
dy

ce

nt

34.

atharali187.blogspot.com

20

11
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01
6

>PEA/Asystole(ACLS):etiologyITCHPAD:
Infarction
Tensionpneumothorax
Cardiactamponade
Hypovolemia/Hypothermia/Hypo,Hyperkalemia/Hypomagnesmia/
Hypoxemia
Pulmonaryembolism
Acidosis
Drugoverdose

ed

ic
a

ls
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ce

nt

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se

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35. >Hypertension:secondaryhypertensioncausesCHAPS:
Cushing'ssyndrome
Hyperaldosteronism[akaConn'ssyndrome]
Aortacoarctation
Phaeochromocytoma
Stenosisofrenalarteries
Note:only5%ofhypertensioncasesaresecondary,restareprimary

atharali187.blogspot.com

11
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36.>Preeclampsia:classictriadPREeclampsia:
Proteinuria
Risingbloodpressure
Edema

37.>PosturalHypotension
HANDI

20

Hypovolaemia/hypopituitarism,

Addisons

ss

io

Neuropathy(autonomic)

se

Drugs(vasodilators/TCADs,diuretics,antipsychotics),

ed

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nt

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Idiopathic

atharali187.blogspot.com

11
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38.>Deepvenousthrombosis:geneticcausesALASCA:
AntithrombinIII
Leiden(FactorV)
APC(ActivatedProteinC)
Sproteindeficiency
Cproteindeficiency
Antiphospholipidantibody

se

ss

io

20

39.>Deepvenousthrombosis:diagnosisDVT:
Dilatedsuperficialveins/Discoloration/Dopplerultrasound
Venographyisgoldstandard
TendernessofThighandcalf

ed

ic
a

ls
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ce

nt

re

40. >Virchow'striad(venousthrombosis)"VIRchow":
Vasculartrauma
Increasedcoagulability
Reducedbloodflow(stasis)

atharali187.blogspot.com

11
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01
6

41. >Myocardialinfarct,complicationsABCDEx2
Arrhythmias/Aneurysm
Bradycardia/BP
Cardiacfailure/cardiactamponade
Dresslers/Death!
Embolism/Extra(VSD,papmusclerupture)

42.Linesoftreatmentofpulmonaryoedema:

20

DOLMA

ss

io

Digoxin,Oxygen,Lasix,Morfine,Aminophylline.(Dolmaisavery
famousfoodinthemiddleeast.)

ce

nt

re

se

43. >M.O.N.A
MONAtreatmentforacuteMI.
Morphine,Oxygen,Nitrate,Aspirin

ed

ic
a

ls
tu
dy

44. >Coronaryarterybypassgraft:indicationsDUST:
Depressedventricularfunction
Unstableangina
Stenosisoftheleftmainstem
Triplevesseldisease

atharali187.blogspot.com

45.

20

11
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6

>AcuteCoronarySyndrome:initialtreatmentABCD:
Aspirin
Betablocker
Coagulation(anticoagulationwithheparin/LMWHeparin)
Doubleproductcontrol(decreaseheartrateandbloodpressure)

46.

ed

ic
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ce

nt

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se

ss

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>MI:therapeutictreatment"OBATMAN!":
Oxygen
Betablocker
ASA
Thrombolytics(egheparin)
Morphine
Aceprn
Nitroglycerin

atharali187.blogspot.com

20

11
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47. >Atherosclerosisriskfactors"You'reaSADBETwiththese
riskfactors":
Sex:male
Age:middleaged,elderly
Diabetesmellitus
BPhigh:hypertension
Elevatedcholesterol
Tobacco

io

re

se

ss

>Thrombus:possiblefatesDOPE:
Dissolution
Organization&repair
Propagation
Embolization

48.

ed

ic
a

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nt

49.

atharali187.blogspot.com

io

20

11
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>CardiovascularriskfactorsFLASHBODIES:
Familyhistory
Lipids
Age
Sex
Homocystinaemia
Bloodpressure
Obesity
Diabetesmellitus
Inflammation(raisedCRP)/Increasedthrombosis
Exercise
Smoking

ed

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se

ss

50.MI:immediatetreatmentDOGASH:
Diamorphine
Oxygen
GTNspray
Asprin300mg
Streptokinase
Heparin

atharali187.blogspot.com

51. Centrally acting anti-hypertensives


M - Methyld dopa

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R - Reserpine
C - Clonidine

20

P Propranolol

52.

io

AMIODARONE - IMPORTANT SIDE EFFECTS

se

ss

PCT - PROXIMAL CONVULATING TUBULE

ce

nt

re

P - PULMONARY FIBROSIS
C- CORNEAL MICRODEPOSITS
T- THROID DISORDERS (hypo/hyperthyroidism)

ls
tu
dy

53. diuretic decreases calcium

ed

ic
a

which diuretic loses calcium in urine..


LOOPS LOSE CALCIUM

atharali187.blogspot.com

54. Side Effects of Aspirin

20

11
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6

ASPIRIN
A: Allergy like reactions e.g. Urticaria
S: susceptibility to bleeding
P: Peptic ulcer
I: Idiosyncratic reactions
R: Reye's syndrome
I: rInging in the ears(tinnitus)
N: Nephropathy

io
se

ss

Mnemonic : HYPER GLUC


Hyper = Increased

55. Side Effects of Thiazide Diuretics

ed

ic
a

ls
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ce

nt

re

G = Glucose
L = Light-headedness (orthostatic hypotension/ low vol/ low sodium)
U = Uricemia
C = Calcemia

atharali187.blogspot.com

56. Anti-hypertensives used in emergencies

20

11
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01
6

Saurav Ganguly HELP


S-sodium nitroprusside
G-Glyceryltrinitrate
H-hydralazine
E-esmolol
L-labetalol
P-phentolamine

57. anti-hypertensives giving in pregnancy

se

ss

io

anti-hypertensives given in pregnancy -3Cs -Ca channel


blocker,cardioselective b-blocker,central sympatholytic-clonidine.

nt

ls
tu
dy

H:Hydralazine
P:Propofol
N:Nebivolol

ce

Highly Pro Nitric

re

58. Nitric oxide donors

ed

ic
a

And the rest :Na nitroprusside,Organic nitrates,Nitrites.

atharali187.blogspot.com

59. heparin

20

11
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H=HYPERSENSITIVITY & hyperkalemia


E=excessive beeding
P=PROLONG APTT
A=ALOPECIA
R=REDUCED PLATELET & BONE MASS
i.e.thrombocytopenia osteoporosis
I=i.v. route
N=aNtagonise by protamine sulphate

ss

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60. digitalis

re

se

Digitalis toxicity is aggravated by KOMAR (READ IT AS KUMAR) of


CaLIFORNIA

ls
tu
dy

ce

nt

KOM-hypoka,hypoxe,hypomag
Advance age
Reanal insufficiency
California in block letters suggest hyperCALCEMIA

ed

ic
a

KEEP ON REVISING...

atharali187.blogspot.com

61. drugs contraindicated in heart failure

11
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Napolean _Narcotics including Opioids


Bonaparte _Benzodiazepines
Says_Salicylates
Hello_Hypnotics
To _Tranquilizers
Don_Diuretics

20

62. fibrinolytics

ss
se
re

ed

ic
a

ls
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ce

nt

S-STREPTOKINASE
T-TENECTEPLASE
U-UROKINASE
A-ALTEPLASE
R-RETEPLASE
t

io

STUART

atharali187.blogspot.com

63. Side effects of Spironolactone


I May Have Got Additional Potassium.

20

11
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6

I=Impotence
M=Menstrual irregularities
H=Hirsuitism
G=Gynaecomastia
A=Acidosis
P=Peptic ulcer(aggravates)

And last but not the least is the pnemonic itself states the main sideeffect=Hyperkalemia

ed

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Queen Proclaims Diso'sPyramid


QUINIDINE
PROCAINAMIDE
DISOPYRAMIDE

ss

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64. antiarrythmic class I A

atharali187.blogspot.com

65. antiarrythmic class I B


IBuy Lido's Mexican Toffees

11
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IB=
Lidocaine
Mexiletene
Tocainide

n
io

ls
tu
dy

ce

nt

EAST

Amiloride

ss
se

re

67. K sparing diuretscs

Epleranone

20

66. antiarrythmic class I C


Fleeting Programme Maker
Flecainide
Propafenone
Moricizine

Spironolactone

ed

ic
a

Triameterene

atharali187.blogspot.com

1. Antibiotics contraindicated during pregnancy


MCAT:

20

Metronidazole

11
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Chemo-Pharma

Chloramphenicol

io

Aminoglycoside

se

ss

Tetracycline

re

2. Etoposide: action, indications, side effect

ce

Action:

nt

"eTOPoside":

ls
tu
dy

Inhibits TOPoisomerase II
Indications:

Testicular carcinoma

ed

ic
a

Oat cell carcinoma of lung

atharali187.blogspot.com

Prostate carcinoma
Side effect:

11
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Affects TOP of your head, causing alopecia


3. Bleomycin: action
"Bleo-Mycin Blows My DNA to bits":

Bleomycin works by fragmenting DNA (blowing it to bits).

20

My DNA signals that its used for cancer (targeting self cells)

io

4. major side effects of isoniazid

ed

ic
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nt

re

se

ss

isoniazid or isonicotinic acid hydrazide(INH)


I-INSANITY(psychosis)
N-NEURITIS(peripheral neuritis)
H-HEPATITIS

atharali187.blogspot.com

5. antipseudomonal aminoglycosides
a small one. antipseudomonal aminoglycosides:

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mnemonic: TAG
T: tobramycin
A: amikacin

20

G: gentamycin

ed

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amphotericin B- SAM (name)


S-Sporotrichosis
A-Actinomycosis
M-Mucormycosis
Itraconazole PChB (phy,chem,bio)
P-Paracoccididomycosis
Ch-chromomycosis
B-Blastomycosis
Ampho+5FC DC & CC (jingle)
DC-dissem. candidiasis
CC-cryptococcosis
amph/itr HP-histoplasmosis

ss

io

6. antifungals-DOCs

atharali187.blogspot.com

20
n
io
ss

SPECTRUM OF ACTION
A-Amoebiasis
B-Bacteroides fragilis
C-Clostridium perfringens
D-Dracunculus medinensis
E-Pseudomembranus Enterocolitis
F-Fusobacterium
G-Giardiasis
H-Helicobacter Pylori
S-Anaerobic Streptococci
T-Trichomonas

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7. METRONIDAZOLE-SPECTRUM OF ACTION

se

8. Rifampin

ed

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nt

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4R's
RNA polymerase inhibitor
Revs up Microsomal P450
Red/Orange body fluids
Rapid Resistance if used alone

atharali187.blogspot.com

9. Uses of cotrimoxazole

20

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Utre: Urinary Tract Infections


Reti: Respiratory tract infections
par
Tight: Typhoid
Body: Bacterial Diarrhoeas & Dysentery
lekar, jab
Chance: Chancroid
Gine: Granuloma Inguinale
Ap: Agranulocytosis patients
PC: Pneumocystis carinii
par

ed

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KAPIL DeV to BAT


K - Kidney damage
A - Antianabolic effect
P - Photoxicity
I - Increased intracranial pressure
L - Liver damage
De - Diabetes insipidus
V - Vestibular toxicity
to
BAT - Bones And Teeth

ss

io

10. s/e of tetracyclines

atharali187.blogspot.com

11. Adverse effects of chloramphenicol


Adverse effects of Chloramphenicol-

11
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BIG Super Hypersensitivity


B- Bone marrow depression

I- Irritative effects like nausea, vomiting, diarrhoea, pain on injection

20

G- Gray baby syndrome

io

Super- super infections

ed

ic
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nt

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se

ss

Hypersensitivity reactions like rashes, fever, angioedema

atharali187.blogspot.com

12. uses of tetracyclines

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Uses of tetracyclines - (used as 1st choice drugs in- )


V Are B.R. Chopra Productions
V -Venereal diseases (lymphogranuloma venerum and granuloma
inguinale)
Are- Atypical pneumonia due to mycoplasma pneumoniae

20

B - brucellosis tretment

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R- Rickettsial infections, Relapsing fever

ss

Chopra- Cholera

ed

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se

Productions- Plague

atharali187.blogspot.com

13. bactericidal drugs


I M Bactericidal Because A Very Quiet Person is Rarely Protected

ed

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Isoniazid
Metronidazole
Beta lactams
Bacitracin
Aminogycosides
Vancomycin
Quinolones
Pyrazinamide
Rifampin
Polymyxin

atharali187.blogspot.com

14. bacteriostatic drugs

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Static Causes Non Total Or Non Complete Though Massive


Elimination

re

15. antibiotics c/I in pregnancy

se

ss

io

20

Sulfonamides
Chloramphenicol
Nitrofurantoin
Tetracyclin
Oxazolidinon
Novobiocin
Clindamycin
Trimethoprim
Macrolide
Ethambutol

ed

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SAFETY
S - SULPHONAMIDES
A - AMINOGLYCOSIDES
F - FQs
E - ERYTHROMYCIN ESTOLATE
T - TETRACYCLIN
Y clindamYcin

atharali187.blogspot.com

16.antitubeculosis drugs
SPIRE

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S..............STREPTOMYCIN
P...............PYRIZINAMIDE
I...............ISONIAZIDE
R,.............RIFAMPICIN
E...............ETHAMBUTOL

20

17. macrolides

ed

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nt

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RACE
R-roxithromycin
A-azitromycin
C-clarithromycin
E-erythromycin.

atharali187.blogspot.com

20
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First line drugs.


(PRIEST)
Pyrazinamide
Rifampin
Isoniazid
Etambutol
STreptomycin
second line drugs
(Please TAKE Carbon Copy)
Paraamino salicylic acid
Thiacetazone
Amikacin
Kanamycin
Ethinamide
Capreomycine
Cycloserine
Newer drugs.
(CAR Of Century)
Ciprofloxacin
Azithromycin
Rifabutin
Ofloxacin
Clarithromycin

11
-2
01
6

18. Antitubercular drugs. K.D.Tripathi

atharali187.blogspot.com

19. anti psedomonal drugs

11
-2
01
6

Amin Beta Pseudo Polyp Roq!

Amin-Aminoglycosides
Beta-beta lactams

20

Pseudo-pseudomonas

io

Roq-fluoROQuinolones

se

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MY FAITH is NEUROTOXIC
MY-MYelosuppression
F-Flu like symptoms
A-Alopecia
I-Interstitial nephritis
T-Thyroiditis
H-Hepatotoxicity
is
NEUROTOXIC

ss

20. ADR of Interferons

atharali187.blogspot.com

21. Penicillin DOC in

ed

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11
-2
01
6

"P.M.(Prime Minister) Pass List of An Strict Act of Superfast Train's Tt."


P-Pneumococci
M-Meningococcal meningitis
Pass-Pasturella multocida
List-Listeria
An-Anthrax
Strict-Streptococci
Act-Actinomyces
Superfast-Syphillis
Train's-Trench fever
Tt-Tetanus

atharali187.blogspot.com

ed

20
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From K.D. Tripathy


ALKYLATING AGENTS: TANEN / NEAT N
Triazine: Dacarbazine
Alkyl Sulfonate: Busulfan
Nitrosoureas: Carmustine
Lomustine
Ethylenimine: Thio- TEPA
Nitrogen Mustards: MCI CM
Mechlorethamine
Cyclophosphamide
Ifosfamide
Chlorambucil
Melphalan
VECTA
Vinca Alkaloids: Vincristine
Vinblastine
Epipodophyllotoxin: Etoposide
Camptothecin Analogues: Irinotecan
Topotecan
Taxanes: Paclitaxel
Docetaxel
Anti metabolites:
Folate Antagonist: Methotrexate
Purine Antagonist: F ATM
Fludarabine
Azathioprine
6- Thioguanine
6- Mercaptopurine
Pyrimidine Antagonist: 5- FU
Cytarabine

11
-2
01
6

22. Anticancer drugs

atharali187.blogspot.com

11
-2
01
6
20
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Antibiotics: ADD MMB/ DMD MBA


Actinomycin D
Doxorubicin
Daunorubicin
Mitomycin C
Mitoxantrone
Bleomycin
Misc: HPCL I
Hydroxyurea
Procarbazine
Cisplatin
Carboplatin
L- Asparaginase
Imatinib
Lastly Drugs altering Hormonal Milieu

atharali187.blogspot.com

23. erythromycin uses

11
-2
01
6

it is used against..
' pure dairy white chocolate'
pure- pneumonia
dairy- diphtheria
white- whooping cough
chocolate- chancroid
24. ANTI-MALARIAL DRUGS

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4-aminoquinolines
quinoline-methanol
cinchona alkaloids
biguanades
diaminopyramidines
8-aminoquinoline
sulfonamides nd sulfone
tetracyclines
amino alcohols
naphthoquinone
sesquiterpine lactones

20

"A Q can B D Answer Surely bt Teacher make's Answer NonSense"

atharali187.blogspot.com

20
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SULPHONAMIDES
S=Steven johnson syndrome
U=urtecaria
L=Leukopenia
P=Photo-sensitivity
H=Haemolytic anemia/Hepatitis
O=Oobstruction of urinary tract
N=Nausea,Vomiting,diarrhea?Nephritis
A=Agranulocystosis
M=Malaise/Megaloblastic aneamia
I=Increase risk of Kernicterus in new born
D=Depression?drug fever
E+Eosinophilia
S=Skin rashes

11
-2
01
6

25. SULPHONAMIDES

nt

Buy at 30 sell at 50

re

26. antibiotic action on protien synthesis

ce

At aminogycoside tetracycline 30 s ribosome

ed

ic
a

ls
tu
dy

Sell streptomycin erythromycin lincosamide linasolide 50 s ribosome

atharali187.blogspot.com

27. Doxycycline DOC

11
-2
01
6

RELY on RICH doxy


RElapsing fever
LYmes disease
RIkketsial infections
CHlamydial infections
conditions where Doxycycline is drug of choice

20

28. penicillinase resistant penicillin

C - cloxacillin

ss

io

O - oxacillin

se

N - nafcillin

re

D - dicloxacillin

ce

ed

ic
a

ls
tu
dy

M mezlocillin

nt

atharali187.blogspot.com

29. Oncology (Monoclonal antibodies in chemotherapy)


BAC TIGeR

11
-2
01
6

B-BeVacizumab
A-Alemtuzumab
C-Cetuximab

20

T-Trastuzumab
I-Ibrituximab
G-Gemtuzumab
R-Rituximab

io
ss
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re

T drugs against bacteroids


CefaTetan
CefameTazole
CefaxiTin

30. cepholo against bacteroids

atharali187.blogspot.com

31. DAPTOMYCIN

11
-2
01
6

DAPTOMYCIN
D-depolarisation ( MOA)
A-all infections
P-pulmonary surfactant is it's inhibitor
TO-TO be avoided in pneumonia
MY- Myopathy
CIN-CI dal (bactericidal )

20

32. MRSA

ce

nt

re

se

ss

io

Drugs effective in MRSA


Victoria Terminal Se Lekar Dadri Root is Closed
Vancomycin
Teicoplanin
Streptogramins
Linezolide
Daptomycine
Cotrimoxazole
Rifampicin

ed

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33. AMPHTERICIN B

atharali187.blogspot.com

io

20

11
-2
01
6

A nemia
M uscle spasms
P hlebitis
H eadaches/hypotension/hypokalemia
T hrombocytopenia
E mesis, encephalopathy
R espiratory strida
I ncreased temperature (fever)
C hills
I mmediate hypersensitivity (anaphylaxis)
N ephrotoxicityimportant!
B ronchospasm

ss

34.NNRTIs (Edited, New)

se

Isha Virani never remembers to pin up her dress

ed

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nt

re

Isha virani is for ifavirenz,


never remembers is for nevirapine
d in the dress means delaviridine.

atharali187.blogspot.com

35. NRTIs (New, edited)


Its for remembering NRTIs category drugs,

io

20

Abaca is for abacavir!


Zoo is for Zalcitabine!
Ass that is "a" is for "azt" and "S" is for stavudine!
Lambs is for Lamivudine!
Dianosaures is for Didanosine

11
-2
01
6

Abaca's (Abaca is an african negro man! just to remember) African


Zoo for Ass , Lambs and Dianosaurs .

ss

36. ANTIVIRAL drugs are:


Acyclovir

| in herpes infection except

Nevirapine & Nelfinavir

Trifluridine

Idoxuridine

| infection

Vidarabine

se

| which are used in HIV

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| Nevirapine & Nelfinavir

atharali187.blogspot.com

Indinavir

| Protease

Ritonavir

| inhibitors

11
-2
01
6

| in HIV
| infection
A

AZT or Zidovidine

Lamivudine

| Reverse transcriptase

20

| inhibitors

io

37. Uses of Fluoroquinolones (shared by Gajanan Taywade)

ed

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se

ss

{3G SPECTRUM CT}

atharali187.blogspot.com

20

11
-2
01
6

3G: Gonorrhoea, Gastroenteritis & Gram -ve Infections


S: Septicemia
P: Prophylaxis
E: Enterocolitis
C: Chancroid
T: Typhoid
R: RTI
U: UTI
M: Meningitis
C: Conjunctivitis
T: Tuberculosis

io

38. RIBAvirin:

se

ss

RSV
Influenza B

nt

re

Arenaviruses (Lassa, Bolivian, etc.)

ls
tu
dy

ce

39. Cephalosporins are active against many bacteria, but these


special bacteria make them CALM (Ineffective)
remembr: CALM

ed

ic
a

C=CLAUSTRIDIUM

atharali187.blogspot.com

11
-2
01
6

A=ACTIVE ENTEROCOCCI
L=LISTERIA MONOCYTOGENES
M= MRSA (METHICILLIN RESISTENT STAPHYLOCOCCI

40. antihelmenthic

io

20

for tapeworm
DIFFICULT - DISCHLORPHEN
QUESTION - QUINACRINE
NOT - NICLOSAMIDE
ANSWERED ASPIDIUM

se

ss

41. antihelminthic

ls
tu
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nt

re

for roundworm
PRESS -PIPERAZINE
THE -THIABENDAZOLE
HANDLE - HEXYLRESORCINOL
OF - OIL OF CHENOPODIUM
SIDE - SENTONIN
DOOR DIETHYLCARBAMAZINE

ed

ic
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42. antibiotics,atntiviral and antifungal causing nephrotoxicity

atharali187.blogspot.com

11
-2
01
6

Mnemonic: SIGMA CAT FAG

Sulfonamides
Indinavir
Ganciclovir

20

Metronidazole

io

Acyclovir

ss

Cidofovir

nt
ce

Foscarnet

re

Tetracyclines

se

Aminoglycosides

ls
tu
dy

Amphoterican B

Glycopeptides (Vancomycin)

ed

ic
a

44.antibiotics inhibiting 30s vs 50s

atharali187.blogspot.com

buy AT 30, CCELL at 50

11
-2
01
6

30S:
Aminoglycosides (gentamicin, amikacin, streptogramin, tobramycin)
[bacteriocidal]
Tetracyclines [bacteriostatic]

ss

io

20

50S:
Chloramphenicol [bacteriostatic]
Clindamycin [bacteriostatic]
Erythromycin [bacteriostatic]
Lincomycin [bacteriostatic]
Linezolid [variable]

se

45.target of first generation cephalosporins

nt
ce

ls
tu
dy

Proteus
E. coli
Klebsiella

re

PEcK

ed

ic
a

46.target of 2nd generation cephalosporins

atharali187.blogspot.com

HEN PEcKS

11
-2
01
6

H. flu
Enterobacter
Nesseria

ss

io

20

Proteus
E. coli
Klebsiella
Serrati

re

se

47.side effects of vancomycin

nt

NOT

ls
tu
dy

ce

Nephrotoxicity
Ototoxicity
Thrombophlebitis ("red man" syndrome)

ed

ic
a

48.drugs for pseudomonas

atharali187.blogspot.com

TCP

11
-2
01
6

Ticarcillin
Carbenicillin
Piperacillin
Also 3rd gen cephs

Ampicillin/amoxicillin HELPS kill enterococci

nt

re

se

ss

io

H. flu
E. coli
Listeria
Proteus
Salmonella
enterococc

20

49.spectrum of ampicillin/amoxicillin

ed

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50.properties og aminoglycoside

atharali187.blogspot.com

Mean" GNATS cannot kill anerobes

11
-2
01
6

"Mean" = bacteriocidal
Gentamicin
Neomycin
Amikacin
Tobramycin
Streptomycin

20

Require O2 for uptake, therefore they are not effective against


anaerobes

io

NOT

re

se

ss

Nephrotoxic (esp when used with cephs)


Ototoxic (esp when used with diuretics)
Teratogen

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51.tetracyclin are effective against

atharali187.blogspot.com

VACUUM THe BedRoom

io

20

11
-2
01
6

Vibrio
Acne
Chlamydia
Ureaplasma
Urealyticum
Mycoplasma
Tularemia
H. pylori
Borrelia
Rickettsia

se

ss

52. ChloramPhenicol:
The only one with a P, thus the only one inhibiting Peptide
bond formation (by peptidyltransferase).

ce

nt

re

53. Macrolides:
Prevent the Movement of ribosomes.
Prevents translocation.

ed

ic
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54. Tetracyclines (TTC):


tRNA Tries but cant.
Prevents the aminoacyl-tRNA from attaching to the A site of the
ribosome.

atharali187.blogspot.com

11
-2
01
6

55. Clindamycin:
Makes ribosomes Cling to mRNA.
Prevents translocation

CNS Pharma

1.effects via Mu opiates receptors

20

"SACRUM"
Sedation

Analgesia

Constipation

Respiratory depression

Euphoria

Miosi

nt

re

se

ss

io

ls
tu
dy

S.O.M.A.T.I.C "

ce

2.antipsychotics:uses

Schizophrenia

Organic brain syndromes

ed

ic
a

atharali187.blogspot.com

Mania

Anxiety

Tetanus

Intractable cough

Control of vomiting

11
-2
01
6

20

3.lithium adverse effects

io

LITHIUM"
Lethargy / Leucocytosis

Intentional Tremor

Teratogenicity

Hypothyroidism

Insipidus [Diabetes insipidus]

Urine excess

ls
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nt

re

se

ss

Metallic taste

ed

ic
a

4.morphine adverse effects

atharali187.blogspot.com

Miosis

Oliguria

Respiratory depression

Pruritus

Hypotension

Infrequency (constipation)

Nausea

Emesis (Vomiting)

ss

io

20

11
-2
01
6

MORPHINE "

se

5.lithium uses

re

LIBRA '
Leukopenia

Inappropriate ADH secretion syndrome (SIADH)

Bipolar disorder

ls
tu
dy

ce

nt

Recurrent neuropsychiatric syndrome

Agranulocytosis

ed

ic
a

atharali187.blogspot.com

6. drugs for alzheimer

11
-2
01
6

DR.GangaTejwani
d=donepezil
r=rivastigmine
g=galantamine
t=tacrine

20

7. s/e phenytoin

adverse effect of phenytoin:

ed

ic
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nt

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se

P-450 interaction
Hirsutism
Enlarged gums
Nystagmus
Yellow skin(discolouration)
Teratogenicity
Osteomalacia
Interference with B-12 metabolism
Neuropathies-ataxia,vertigo

ss

io

PHENYTOIN

atharali187.blogspot.com

8. antiepileptics' classification

11
-2
01
6

B - barbiturates D-deoxybarbitarates
H - hydantoin I - iminostilbene
S - succinamide A-aliphatic carbxylic acid
B -benzodiazepines
C - cyclic GABA analogue
P - phenyl triazine
N - newer drugs

20

BD HISAB Ce PiNa

io

se
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ed

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ce

nt

Olanzapine (Zyprexa)
Risperidone (Risperdal)
Clozapine (Clozaril)
Aripiprazole (Abilify)
(Seroquel) Quetiapine

ss

ORCAS (Brand names in parentheses)

9. ATYPICAL ANTIPSYCHOTICS

atharali187.blogspot.com

10. Side effects of clozapine

11
-2
01
6

Side effects of clozapine MASS


M myocarditis
A agranulocytosis*
S seizures
S sialorrhea

io
ss

12. Adverse effects of Diazepam

20

11. short acting BZDs


TOM
Triazolam
Onazelam
Midazolam

ed

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se

ADVERSE effects of Diazepam-DIAzEPAN


D-Dizziness,disorientation,dry mouth
I-impaired vision
A-Amnesia
z
E-elderly
P-Psychomotor skill impairment
A-Ataxia, apnoea in sleep
N-Neonatal resp depression, night awakening

atharali187.blogspot.com

13. PHENYTOIN ADVERSE EFFECT

n
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ss

14. Adv. effects of Carbamazepine

20

M- MEGALOBLASTIC ANEMIA
A- ATAXIA
L- LYMPHDENOPATHY
I- INHIBIT INSULINE
K- VIT K DEFICIENCY
A- ARRYTHMIA

11
-2
01
6

HOT MALIKA
H- HIRSUTISM N HYPERTROPHY OF GUM
O- OSTEOMALACIA
T-TERATOGENICITY

nt

ls
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dy

ce

C-Confusion
A-Ataxia
R-Rashes
B-Blurring of vision
A-Aplastic anaemia

re

se

Adv effecta of Carbamazepine(anti-epilepsy)


Mnemonic- CARBA MEAN

15.Parkinsonism management

ed

ic
a

SALAD

atharali187.blogspot.com

Selegline
Anticholinergics(trihexyphenidyl,benztropine)

Amantididne

11
-2
01
6

L.dopa +decarboxylase(carbidopa)

Dopamine receptor agonists(bromocriptine,pergolide)

ed

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se

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20

16. MAOIs: indications MAOI'S:


Melancholic [classic name for atypical depression]
Anxiety
Obesity disorders [anorexia, bulemia]
Imagined illnesses [hypochondria]
Social phobias
Listed in decreasing order of importance.
Note MAOI is inside MelAnchOlIc.

atharali187.blogspot.com

io
ss

re

se

18. SSRIs: side effects SSRI:


Serotonin syndrome
Stimulate CNS
Reproductive disfunctions in male
Insomnia

20

11
-2
01
6

17. Opioids: effects BAD AMERICANS:


Bradycardia & hypotension
Anorexia
Diminished pupilary size
Analgesics
Miosis
Euphoria
Respiratory depression
Increased smooth muscle activity (biliary tract constriction)
Constipation
Ameliorate cough reflex
Nausea and vomiting
Sedation

ed

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ls
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nt

19. Inhalation anesthetics SHINE:


Sevoflurane
Halothane
Isoflurane
Nitrous oxide
Enflurane
If want the defunct Methoxyflurane too, make it MoonSHINE.

atharali187.blogspot.com

20. Benzodiazapines: ones not metabolized by the liver (safe to use in


liver failure) LOT: Lorazepam Oxazepam Temazepam

11
-2
01
6

21. Benzodiazepines: actions


"Ben SCAMs Pam into seduction not by brain but by muscle":
Sedation
anti-Convulsant
anti-Anxiety
Muscle relaxant
Not by brain: No antipsychotic activity.

se

ss

io

20

22. Benzodiazepenes: drugs which decrease their metabolism


"I'm Overly Calm":
Isoniazid
Oral contraceptive pills
Cimetidine
These drugs increase calming effect of BZDs by retarding
metabolism.

ed

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nt

re

23. Anesthesia: 4 stages "Anesthesiologists Enjoy S & M":


Analgesia
Excitement
Surgical anesthesia
Medullary paralysis

atharali187.blogspot.com

11
-2
01
6

ce

nt

re

se

ss

io

25. Methyldopa:
side effects METHYLDOPA:
Mental retardation
Electrolyte imbalance
Tolerance
Headache/ Hepatotoxicity psYcological upset
Lactation in female
Dry mouth
Oedema
Parkinsonism
Anaemia (haemolytic)

20

24. Sodium valproate: side effects VALPROATE:


Vomiting
Alopecia
Liver toxicity
Pancreatitis/ Pancytopenia
Retention of fats (weight gain)
Oedema (peripheral oedema)
Appetite increase
Tremor
Enzyme inducer (liver)

ls
tu
dy

26.benzodiazepine actions
SAMA

ed

ic
a

Sedation

atharali187.blogspot.com

Anticonvulsive
Muscle relaxant

11
-2
01
6

Anti-anxiety
27.Benzodiazepine side effects
5 As
Addiction

20

Additive sedation
Amnesia

io

Ataxia

ss

Abjection (depression)

re

SHINED

ce

ls
tu
dy

isoflurane

nt

Sevoflurane
Halothane

se

28. Gen anesthetics

NO

Enflurane

ed

ic
a

Desflurane

atharali187.blogspot.com

11
-2
01
6

Endocrinology

1.Pituitary hormones

ss

io

20

FLAGTOP:
Follicle stimulating hormone
Lutinizing hormone
Adrenocorticotropin hormone
Growth hormone
Thyroid stimulating hormone
Oxytocin
Prolactin

se

2.progestorone actions

ls
tu
dy

ce

nt

re

PROGESTE:
Produce cervical mucous
Relax uterine smooth muscle
Oxycotin sensitivity down
Gonadotropin [FSH, LH] secretions down
Endometrial spiral arteries and secretions up
Sustain pregnancy
Temperature up / Tit development
Excitability of myometrium down

ed

ic
a

3.Hyperthyroidism sign and symptoms

atharali187.blogspot.com

20

11
-2
01
6

THYROIDISM:
Tremor
Heart rate up
Yawning [fatigability]
Restlessness
Oligomenorrhea & amenorrhea
Intolerance to heat
Diarrhea
Irritability
Sweating
Musle wasting & weight loss

4.adrenal gland functions

nt

re

se

ss

io

ACTH:
Adrenergic functions
Catabolism of proteins/ Carbohydrate metabolism
T cell immunomodulation
Hyper/ Hypotension (blood pressure control)

ed

ic
a

ls
tu
dy

ce

5.oestrogen functions

atharali187.blogspot.com

20

11
-2
01
6

OESTROGEN SUX:
Organ development (sex organs)
Endocrine: FSH and LH regulation
Secondary sex characteristics development
Tropic for pregnancy
Receptor synthesis (of progesterone, oestrogen, LH)
Osteoporosis decrease (inhibits bone reabsorption)
Granulosa cell development
Endocrine: increases prolactin secretion, but then blocks its effect
Nipple development
Sex drive increase
Uterine contractility increase
oXytocin sensitivity increase

ed

ic
a

ls
tu
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ce

7.Hypercalcemia

nt

re

se

RNAs
Renin-angiotensin m echanism
Na concentraton in blood
ANP (atrial natriuretic peptide)
Stress

ss

io

6.aldosterone:regulation of secretion from adrenal cortex

atharali187.blogspot.com

11
-2
01
6

Bones, Stones, Groans, Moans":


Bones: pain in bones
Stones: renal
Groans: pain
Psychic moans/ Psychological overtones: confused state
8.Pheocromocytoma

20

PHEochromocytoma":
Palpitations
Headache
Edisodic sweating (diaphoresis)

9.Thyroid carcinoma

ed

ic
a

ls
tu
dy

ce

10.thyroid storm

nt

re

se

ss

io

Most Popular is Papillary.


Clinical features:
Papillae (branching)
Palpable lymph nodes
"Pupil" nuclei (Orphan Annie)
Psammoma bodies within lesion (often)
Also, has a Positive Prognosis (10 year survival rate: 98%)

atharali187.blogspot.com

11
-2
01
6

Storm HITS girls cAMP":


Thyroid storm due to:
Hyperthyroidism
Infection or Illness at childbirth
Trauma
Surgery
girls: Thyroid storm more common in females.
cAMP: Tx involves high dose of beta blockers (beta receptors work
via cAMP)

ed

ic
a

ls
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nt

12.cushing synjdrome

re

se

ss

io

A SCHISM among the Axis during WWII":


Addison disease
Subacute thyroiditis
Cretinism/ Cold intolerance/ Constipation
Hashimoto's disease
Infectious-subacute thyroiditis
Silent thyroiditis
Myxedema coma

20

11.hypothyroidism

atharali187.blogspot.com

11
-2
01
6

CUSHING:
Central obesity/ Cervical fat pads/ Collagen fiber
weakness/ Comedones (acne)
Urinary free corisol and glucose increase
Striae/ Suppressed immunity
Hypercortisolism/ Hypertension/ Hyperglycemia/ Hirsutism
Iatrogenic (Increased administration of corticosteroids)
Noniatrogenic (Neoplasms)
Glucose intolerance/ Growth retardation

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13.addison disease

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se

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ADDISON:
Autoimmune
DIC (meningcoccus)
Destruction by cancer, infection, vascular insufficiency
Iatrogenic
Sarcoidosis, granulomatous such as TB histiomycosis
hypOtension/ hypOnatermia
Nelson's syndrome [post adrelectomy, increased ACTH]

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14.Goiter

atharali187.blogspot.com

15.dibetes complicatins

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SHAKE:
Stroke
Heart attack
Amputations
Kidney disease
Eyes (vision loss)

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GOITRE:
Goitrogens
Onset of puberty
Iodine deficiency
Thyrotoxicosis/ Tumor/ Thyroiditis [Hashimoto's]
Reproduction [pregnancy]
Enzyme deficiencies

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16.steroid side effects

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CUSHINGOID
Cataracts

Ulcers

Skin: striae, thinning, bruising

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Hypertension/ Hirsutism/ Hyperglycemia

Infections

Necrosis, avascular necrosis of the femoral head

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Glycosuria

Osteoporosis, obesity

Immunosuppression

Diabetes

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17.growth hormone toxicity

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HE-SSP
Hyperglycemia

Scoliosis

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nt

Pseudomotor cerebri

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Slipped capital femoral epiphysis

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Edema

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PMA

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18.growth hormone toxicity in adults

Peripheral edema
Myalgia

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Athralgia

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19.Follitropin alfa and Hcg toxicity

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OMG-Humna Doing Exercise


Ovarian hyperstimulation
Multiple pregnencies
Gynecomestia in MEN

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Headach
Deoression

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Edema

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20.amidarone side effects

ls
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6 P's:
Prolongs action potential duration
Photosensitivity
Pigmentation of skin
Peripheral neuropathy
Pulmonary alveolitis and fibrosis
Peripheral conversion of T4 to T3 is inhibited -> hypothyroidism
21.oxytocin side effects

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Hair-PUFF

atharali187.blogspot.com

Hypotension
Placental abruption

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Uterine rupture
Fetal distress
Fluid retension
22.prednisone toxicity

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BG-SMOAG
Behavioural changes

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Glucose intolerance

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Salt retension

Osteoprosis

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Growth Inhibition

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Adrenal suppression

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Muscle wasting

23.Fludocortisoe-toxicity
CSS

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Cogestive heart failure

atharali187.blogspot.com

Salt and fluid retension


Symptoms of glucocorticoid

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23.Tamoxifere-toxicity
THE
Thromboembolism
Hot flushes

20

Endometrial
24.Anastrozole-toxicity

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A-ROAD-MATCH

re

Osteoarthritis

ce

nt

Arthritis
Disk herniation

se

Reduced bone mineral density

ss

Athralgia

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Musculoskeletal Disorders
Arthrosis

Cervical spondylosis

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Hot flushes

atharali187.blogspot.com

25.Prednisone clinical applications


HOM

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Hematalogic cancer
Organ transplantation
Many inflammatory conditions
26. Hormones that Increase Blood Glucose

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"STENGG"

nt

27.PTU-mechanism

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Somatotropin (growth hormone)


Thyroid hormones (thyroxine and triiodothyronine)
Epinephrine
Norepinephrine
Glucagon
Glucocorticosteroids

ls
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It inhibits PTU:
Peroxidase/ Peripheral deiodination
Tyrosine iodination
Union (coupling)

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28.steroid side effects

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29.insulin mixing

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BECLOMETHASONE:
Buffalo hump
Easy bruising
Cataracts
Larger appetite
Obesity
Moonface
Euphoria
Thin arms & legs
Hypertension/ Hyperglycaemia
Avascular necrosis of femoral head
Skin thinning
Osteoporosis
Negative nitrogen balance
Emotional liability

ls
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"Not Ready, Ready Now":


Air into NPH
Air into Regular
Draw up Regular
Draw up NPH

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30.coricosteroid side effects

atharali187.blogspot.com

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ls
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OLPER(milk )

Lansoprazole

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re

1. the PPIs

Omeprazole

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ss

GIT-Pharma

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CUSHINGS BAD MD:


Cataracts
Up all night (sleep disturbances)
Suppression of HPA axis
Hypertension/ buffalo Hump
Infections
Necrosis (avascular)
Gain weight
Striae
Bone loss (osteoporosis)
Acne
Diabetes
Myopathy, moon faces
Depression and emotional changes

Pantoprazole

ed

ic
a

Rabeprazole

atharali187.blogspot.com

Esomeprazole
2.types of laxatives

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Types of laxatives
"Boss"

20

Bulk laxatives.
Osmotic laxatives.
Stimulant(irritant)laxatives.
Stool Softeners.

se

ls
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nt

re

Bulk laxatives.
irritant(Stimulant)laxatives.
Osmotic laxatives.
Stool Softeners.

ss

io

Or "Bios"

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ASTHMA-PHARMA

atharali187.blogspot.com

1.management of asthma
ASTHMA

2.asthma participating agents

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DIPLOMAT:
Drugs (aspirin, NSAIDs, beta blockers, etc)
Infections (URTI/LRTI)
Pollutants (at home, at work)
Laughter(emotion)
Oesophageal reflux (nocturnal asthma)
Mites
Activity and exercise
Temperature (cold)

20

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Adrenergics
Steroids
Theophyllines)
Hydration
Mask

atharali187.blogspot.com

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3. Asthma acute attack: 5 life threatening signs SHOCK:


Silent chest
Hypotension
One third of best/predicted PFR
Cyanosis
Konfusion

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5. AAAA PPPP:
Airway obstruction
Angina
Anxiety
Asthma
Pneumonia
Pneumothorax
Pulmonary Edema
Pulmonary Embolus

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4. Asthma: management of acute severe O SHIT:


Oxygen (high dose: >60%)
Salbutamol (5mg via oxygen-driven nebuliser)
Hydrocortisone (or prednisolone)
Ipratropium bromide (if life threatening)
Theophylline (or preferably aminophylline-if life threatening

atharali187.blogspot.com

NSAIDS-PHARMA

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NSAID:
N-ursing and pregnancy
S-erious bleeding
A-llergy/ Asthma/ Angioedema
I-mpaired renal function
D-rug (anticoagulant)

se

2. NSAIDs: contraindications

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1. NSAIDs-classification:
SOFIA PaBe..
S-salicylate
O-oxicame derivatives
F-fenamic acid deri
I-indol deri
A-aryl acetic acid deri
P-propionic acid deri
-pyrrolo pyrrolo deri
-pyrazolon deri
-paramine phenol deri
B-benzoxazocin deri

atharali187.blogspot.com

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Prostaglandin-pharma

atharali187.blogspot.com

PROSTAGLANDINS confusion

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A)All have "1 MISS"


means
MISoprostol is PGE1.
B)cErviprimE has 2E so
cErviprimE is PGE2.

io

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C)DInoproSTONE
DI=2
Remember that "stonE" in both(2) kidney n "stonE" has "E".
So DINOPROSTONE is PGE2.

nt

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D)DINO mario has 2 FArari CAR.


DINO-DINOPROST
2 FArari-F2A [A for Alpha]
CAR-CARBOPROST
so
DINOPROST n CARBOPROST r PGF2alpha

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Note: DINOPROSTONE is PGE2 which is remember by 2 kidney


stonE bt DINOPROST is PGF2alpha.

atharali187.blogspot.com

By

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ALI Zeeshan (QAMC)


ATHAR ALI (QAMC)

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NOREEN FATIMA(FJMC)

ce

GROUP

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our group, page and blog

PAGE

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https://www.facebook.com/gro
ups/Medical.study.centre/

atharali187.blogspot.com

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https://www.facebook.com/pa
ges/Medical-study-centresession-20112016/1451699768417480

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BLOG

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http://atharali187.blogspot.com/

atharali187.blogspot.com

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6

20

atharali187.blogspot.com

atharali187.blogspot.com

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