11/29/2015

ShuXu|LinkedIn

Home

Profile

Searchforpeople,jobs,companies,andmore...

Connections

Interests

Jobs

Advanced

BusinessServices

TryPremiumforfree

OnlineEducationMaster'sLearnHowToDoMoreForStudents.EarnYourM.EdAtLeTourneau.ApplyNow! | ReadMore

ShuXu

3rd

ResearchInstructoratVanderbiltUniversity
GreaterNashvilleArea

Biotechnology

Current

VanderbiltUniversityMedicalCenter

Previous

VanderbiltUniversity,UniversityofToledo,NanjingUniversity

Education

UniversityofToledo

Connect

SendShuInMail

189

connections

https://www.linkedin.com/in/xushu

Background

PeopleAlsoViewed
SouravSarkar

Summary

Ph.D.inbiochemistrywith4yearsresearchexperienceinlieuofdegreeexpertinsightinprotein
expression,purificationandcharacterization,proteinchemistry,structuralbiology,enzymologyandsmall
chemicalcharacterizationbiophysics,ITC,DSC,SPR,DLSproteincrystallizationbioanalytical
chemistryxraycrystallographybiochemicalassay.

ResearchScientistIIIatLehigh
University

DanielScott
AssistantProfessorofChemistryand
BiochemistryatDePauwUniversity

ChaitaliRaskapur
SeniorResearchAssociateatBerg
Pharma

DeLIN

Education

UniversityofToledo
Ph.D.,Chemistry,EnzymologyandProteinChemistry

StaffatTheUniversityofDundee

KongXianjing

20072011
DissertationTitle:PorcineLeukocyte12Lipoxygenase
ResearchAdvisor:Dr.MaxO.Funk
1honororaward
7courses

ZHENYANLIU
Teacherathuahsingchineseschool

AnilDesireddy

ChakraJoshi

Director'sPostdocFellowatLos
AlamosNationalLaboratory,Center
forIntegratedNanotechnologies
(CINT)

ResearchAssistantatTheUniversityofToledo

ShrongShiLin

1recommendation

IhavehadapleasureofknowingShuforthepast3yearsworkinginthesamecompany.Creativeteam
playerthat'sShu!Smartandwisecolleaguewithhugeknowledge.Intelligentandhighlymotivated
persontoworkwith.Histechnicalskillsare... View

associateprofessoratPeking
University

ManishJoshi
ScientistatHenkelAG&Co.KGaA

NanjingUniversity
M.S,Microbiology&BiochemicalPharmaceutics
20042007
NaturalProductCharacterization
ThesisTitle:ResearchandDiscoveryofNewCytochalasins

KebreabGhebreselasie
MRatVandegriftForwarding
Company,Inc.

1honororaward
5courses

NanjingUniversity

HowYoureConnected

You

Bachelor,Biotechnology
20002004

ZhouLing

IntensivePrograminBiochemicalPharmaceutics
1honororaward
14courses,including:

Yourconnectionscanintroduce
youtosomeonewhoknows
Shu
Getintroduced

https://www.linkedin.com/profile/view?id=AAkAAAM4joBRgwr6k3xt3QdAbz5NR1ytGcdjBs&authType=NAME_SEARCH&authToken=BPpX&locale=en_

1/6

11/29/2015

ShuXu|LinkedIn

Experience

ShuXu

ResearchInstructor
VanderbiltUniversityMedicalCenter
January2015Present(11months) | GreaterNashvilleArea
Structuralanalysisforcycloooxygenase2andotherlipidrelatedprotein(Researchfield:protein
chemistry,structuralbiologyanddrugR&D)
Leadingthedeterminationofhighqualityproteincomplexes
DevelopingHTSmethodsformedicinalandbiologicalchemistryintoprojects
Providingtechnicalsupportchemistsandbiologistsinareasofexpertise
Publishedworkinmultiplejournals

InCommonwithShu
Shu

2
Languages

ResearchFellow
VanderbiltUniversity
January2012December2014(3years) | GreaterNashvilleArea
Structuralanalysisforcycloooxygenase2selectiveinhibition
(Researchfield:proteinchemistry,structuralbiologyanddrugR&D)
Ledthedeterminationofhighqualityproteincomplexes
Integratedstructuralbiologyconceptsandexpertiseintocrossfunctionalprojects
Providedtechnicalsupportchemistsandbiologistsinareasofexpertise
DevelopedCOX1specificpolyclonalantibodyincollaborationwithVanderbiltAntibodyandProtein
Resource(VAPR)
Publishedworkinmultiplejournals,eg.JBC,ACSMedChemLett,BioorgMedChemLett,IUBMBLife.

5
Skills&Expertise

1
School

1
Group

ResearchAssistant/TeachingAssistant
UniversityofToledo
August2007January2012(4years6months) | Toledo,OhioArea
Polyunsaturatedfattyacidmetabolismvialipoxygenasecatalysis(Researchfield:proteinchemistry,
enzymologyandcrystallography)
Ledtheproteinexpressandproductionforcrystallizationpipelines
Designednovelproteinconstructstofacilitatecrystallization
Exhibitedindependentscientifictroubleshooting,timemanagementandlaboratoryoperationabilities
TaughtOrganicchemistryLabs(CHEM2460andCHEM2470)
Mentored/Guidedundergraduatestudentsandtechniciansinthelaboratory
PublishedinStructure,Biochemistry,ArchivesofBiochemistryandBiophysics

ResearchAssistant/TeachingAssistant
NanjingUniversity
February2004June2007(3years5months) | Nanjing,Jiangsu,China
DiscoveryandResearchofLeadCompoundsPurification,ScreeningandFermentationofMicrobiology
Isolation,CharacterizationandBioactiveStudiesonSecondaryMetabolites
Performedisolationandelucidationofbioactivemolecules
Multitaskingprojects
Performedbioactiveassayandscreenedpotentialinterestingstrains
Managedandmaintainedbacterialandfungilibrary
PublishedhighimpactpapersinOrganicLettersandChemistry&Biodiveristy

Courses

UniversityofToledo

Xcrystallography
MacromolecularCrystallography
ProteinChemistry
Enzymology
BiochemicalPhysics
AdvancedAnalyticalChemistry
AdvancedBiologicalChemistry

NanjingUniversity

Biochemistry
Pharmacology
Pharmaceutics
MicrobiologyandImmunology
Physiology
Biostatistics
Genetics
MolecularBiology
CellBiology
BiopharmaceuticalAnalysis
PrinciplesofChemicalProcess

https://www.linkedin.com/profile/view?id=AAkAAAM4joBRgwr6k3xt3QdAbz5NR1ytGcdjBs&authType=NAME_SEARCH&authToken=BPpX&locale=en_

2/6

11/29/2015

ShuXu|LinkedIn

OrganicChemistry
InorganicChemistry
PhysicalChemistry

NanjingUniversity

AdvancesinMicrobiology
Zymology
AdvancedPlantBiochemistry
SpectrometricAnalysisofPlantConstituents
AdvancedMolecularBiologyandBiochemistry

Honors&Awards

SantoshNigamMemorialOutstandingYoungScientistAward
EicosanoidResearchFoundation
September2011

2007ExcellentMasterThesisAward,JiangsuProvince
MinistryofEducation,JiangsuProvince,P.R.China
March2008

2004OutstandingBachelorGraduate
NanjingUniversity
June2004

Languages

English

Chinese

Fullprofessionalproficiency

Nativeorbilingualproficiency

Publications

OxicamsBindinaNovelModetotheCyclooxygenaseActiveSiteviaaTwo
watermediatedHbondingNetwork
(
JournalofBiologicalChemistry
L
January14,2014
i
Thefirststructuraldescriptionofcyclooxygenaseoxicamcomplexesrevealanewbindingpocketof
n
inhibitorstocyclooxygenases.
k
)
7authors,including:
ShuXu

DanielJ.Hermanson

ResearchInstructoratVanderbiltUnive

SurajitBanerjee

KebreabGhebreselasie

StaffScientistatNECAT/CornellUniv

CrystalStructureof12LipoxygenaseCatalyticDomainInhibitorComplex
IdentifiesaSubstrateBindingChannelforCatalysis
(
Structure
L
July12,2012
i
Determinedthecrystalstructureof12lipoxygenasecomplexwithasubstrateanalog
n
k
4authors
)
ShuXu

TimothyC.Mueser

ResearchInstructoratVanderbiltUnive
LawrenceJ.Marnett

MaxO.Funk,Jr.

ExploringtheMolecularDeterminantsofSubstrateSelectiveInhibitionof
Cyclooxygenase2byLumiracoxib
Bioorganic&MedicinalChemistryLetters (
L
https://www.linkedin.com/profile/view?id=AAkAAAM4joBRgwr6k3xt3QdAbz5NR1ytGcdjBs&authType=NAME_SEARCH&authToken=BPpX&locale=en_

3/6

11/29/2015

ShuXu|LinkedIn

September6,2013
DesignandEvaluatenovelinhibitorsforsubstrateselectiveinhibitorsforCOX2basedonthescaffoldof
Lumiracoxib
5authors,including:
MatthewA.Windsor

PieterL.Valk

SeniorManager,ScienceCommunicati

SurajitBanerjee

ShuXu

StaffScientistatNECAT/CornellUniv

ResearchInstructoratVanderbiltUnive

SubstrateSelectiveInhibitionofCyclooxygenase2:Developmentand
EvaluationofAchiralProfenProbes
(
ACSMedicinalChemistryLetter
L
August15,2012
i
DesignandEvaluatethescaffoldofachiralprofensforsubstrateselectiveinhibitorsforCOX2
n
k
10authors,including:
)
MatthewA.Windsor

DanielJ.Hermanson

SeniorManager,ScienceCommunicati
PhilipJ.Kingsley

ShuXu
ResearchInstructoratVanderbiltUnive

ActionataDistance:MutationsofPeripheralResiduesTransformRapid
ReversibleInhibitorstoSlow,TightBindersofCyclooxygenase2
(
JournalofBiologicalChemistry
L
March30,2015
i
MembranebindingdomainmutationschangetherapidreversibleinhibitorsofCOX2intoslowtight
n
binders.
k
)
9authors,including:
AnnaL.Blobaum

ShuXu
ResearchInstructoratVanderbiltUnive

ScottW.Rowlinson

SurajitBanerjee
StaffScientistatNECAT/CornellUniv

ComplexesoftheoutermitochondrialmembraneproteinmitoNEETwith
resveratrol3sulfate.
(
Biochemistry
L
May17,2011
i
StudiedtheinteractionbetweenresveratrolandauniqueproteinmitoNEETbyproteinchemistry
n
approaches.
k
)
6authors,including:
WaqarArif

ShuXu
ResearchInstructoratVanderbiltUnive

DraganIsailovic

WernerJ.Geldenhuys

EPRspectroscopyandelectrosprayionizationmassspectrometryreveal
distinctivefeaturesoftheironsiteinleukocyte12lipoxygenase.
(
ArchivesofBiochemistryandBiophysics
L
August14,2009
i
Biochemicalandbiophysicalcharacterizationoftherecombinantleukocyte12lipoxygenase.
n
k
6authors,including:
)
JohannaRapp

ShuXu

ResearchInstructoratVanderbiltUnive
AllanM.Sharp

WendellGriffith
ProteinBiomarkersCore,Universityof

Chaetominine,acytotoxicalkaloidproducedbyendophyticChaetomiumsp.
IFBE015.
(
OrganicLetters
L
November16,2006
i
IdentifiedanalkaloidwithanovelframeworkfromChaetomiumsp.
n
k
)

https://www.linkedin.com/profile/view?id=AAkAAAM4joBRgwr6k3xt3QdAbz5NR1ytGcdjBs&authType=NAME_SEARCH&authToken=BPpX&locale=en_

4/6

11/29/2015

ShuXu|LinkedIn

8authors,including:
ShuXu

RuiHuaJiao

ResearchInstructoratVanderbiltUnive
JunYanLiu

HuiMingGe

CytotoxiccytochalasinmetabolitesofendophyticEndothiagyrosa.
Chemistry&Biodiversity
May8,2009
Discoveredtwonewbioactivecytochalasinsfromanendophyticfugus.
6authors,including:
ShuXu

HuiMingGe

(
L
i
n
k
)

ResearchInstructoratVanderbiltUnive
YongChunSong

YaoShen

13Methylarachidonicacidisapositiveallostericmodulatorof
endocannabinoidoxygenationbycyclooxygenase
(
JournalofBiologicalChemistry
L
February2,2015
i
11authors,including:
n
k
ShalleyKudalkar
PhilipKingsley
)
D.V.M.,Ph.D.
ResearchAssistantatVanderbiltUniver
SpyrosPNikas,

ShuXu
ResearchInstructoratVanderbiltUnive

Oxicams,aclassofnonsteroidalantiinflammatorydrugsandbeyond
IUBMBlife
December1,2014
3authors
ShuXu

CarolA.Rouzer

ResearchInstructoratVanderbiltUnive

(
L
i
n
k
)

LawrenceJMarnett

nidoDicarbaborateInducesPotentandSelectiveInhibitionofCyclooxygenase
2
(
ChemMedChem
L
June18,2015
i
n9authors,including:
k
WilmaNeumann
ShuXu
)
ResearchInstructoratVanderbiltUnive
MenyhrtB.Srosi

MatthiasS.Scholz

TargetedimagingofcancerbyfluorocoxibC,anearinfraredcyclooxygenase2
probe
(
JournalofBiomedicalOptics
L
March13,2015
i
7authors,including:
n
k MdJashimUddin
BrendaC.Crews
)
KebreabGhebreselasie

CristinaKDaniel

Skills

TopSkills

https://www.linkedin.com/profile/view?id=AAkAAAM4joBRgwr6k3xt3QdAbz5NR1ytGcdjBs&authType=NAME_SEARCH&authToken=BPpX&locale=en_

5/6

11/29/2015

ShuXu|LinkedIn

19

ProteinExpression

18

Biochemistry

14

Purification

11

HPLC

10

MolecularBiology

Chemistry

StructuralBiology

28

ProteinChemistry

Characterization

MassSpectrometry

Shualsoknowsabout...
3

Laboratory

Microbiology

Sitedirected...

ITC

SDSPAGE

Xraycrystallography

ProteinPurification

FPLC

MedicinalChemistry

See4+

PCR
NMR

MolecularCloning

GelElectrophoresis

DLS

Chromatography

AdditionalInfo
PersonalDetails
Birthday

November15

Projects

Usetransactiondatatocategorizeclientsbypython

(
L
CapitalOneChallengeParticipant,September2015.SubmittedproposaltoCapitalOneforasmall
i
consultingproject"Usetransactiondatatocategorizeclients"
.DirectLink:
n
https://www.mindsumo.com/solutions/90915
k
)
September2015

Recommendations

Received(1)

Given(2)

Ph.D.
UniversityofToledo
ChakraJoshi
ResearchAssistantatTheUniversityofToledo

IhavehadapleasureofknowingShuforthepast3yearsworkinginthesame
company.Creativeteamplayerthat'sShu!Smartandwisecolleaguewithhuge
knowledge.Intelligentandhighlymotivatedpersontoworkwith.Histechnicalskillsare
brilliant,hasdeepexperienceinsystemsandcommunicationsandisalwaysfocusedtoget
clientssatisfaction.Verypositive... more
November14,2011,ChakrastudiedwithShuatUniversityofToledo

HelpCenter

About

Careers

LinkedInCorporation2015

Advertising

UserAgreement

TalentSolutions
PrivacyPolicy

SalesSolutions
AdChoices

SmallBusiness

CommunityGuidelines

Mobile

Language

CookiePolicy

UpgradeYourAccount

CopyrightPolicy

SendFeedback

https://www.linkedin.com/profile/view?id=AAkAAAM4joBRgwr6k3xt3QdAbz5NR1ytGcdjBs&authType=NAME_SEARCH&authToken=BPpX&locale=en_

6/6