Math1050DrugFilteringLab

Name:TrevorAhSue

Thepurposeofthislabistocomeupwithacontinuousmodelforexponentialdecay.

Dotassumesthatherkidneyscanfilterout25%ofadruginherbloodevery4hours.
Sheknowsthatshewillneedtotakeadrugtestforaninterviewinacoupleofdays.
Sheplansontakingone1000milligramdoseofthedrugtohelpmanageherpain.

1.)Fillinthetableshowingtheamountofthedruginyourbloodasafunctionoftime
androundeachvaluetothenearestmilligram.Thefirsttwodatapointsarealready
completed.

TIMESINCE
TAKINGTHEDRUG
(HR)

AMOUNTOF
DRUGINHER
BLOOD(MG)

1000

750

563

12

422

16

317

20

238

24

179

28

134

32

101

36

76

40

57

44

43

48

32

52

24

56

18

60

14

64

11

68

2.)Useagraphingutilitytomakeaplotoftheabovedata.Labelaxesappropriately.
Copyandpasteyourgraphintothisdocument.

3.)Basedonyourgraph,whatcanyousayaboutthedata?Forexample,istherea
pattern?Isthereconstantslope?

Yestheslopeisconsistent,itisdecreasingby25%every4hours.

4.)HowmanymilligramsofthedrugareinDotsbloodafter2days?

32milligrams

5.)HowmanymilligramsofthedrugareinDotsbloodafter5days?

Approx.0.2milligrams

6.)HowmanymilligramsofthedrugareinDotsblood30hoursaftershetookthe
drug?Explainyourreasoning.

117milligrams,after28hourstherewere134milligramsofthedrugin
Dotsbody.2morehoursandthedrugdrops12.5%to117milligrams.

7.)Abloodtestisabletodetectthepresenceofthisdrugifthereisatleast0.1mgina
personsblood.Howmanydayswillittakebeforethetestwillcomebacknegative?
Explainyouranswer.

After5daysand12hoursor132hourstheresonly0.08milligramsinDots
bloodwhichisunabletobereadinabloodtest.

8.)Willthedrugeverbecompletelyremovedfromhersystem?Explainyourreasoning.
Whatcomplicationsmightarisefromhavingexcessamountsinhersystem?

No,ifthedrugdecreasesby25%every4hoursitcanneverreach0.The
drugwillalwaysbeinDotssystem,justaverysmallamount.

9.)Sincethereisaconstantrateofdecay,acontinuousexponentialdecaymodelcan
beusedtodeterminehowmuchdrugisinhersystematanytime.

Exponential Decay Model

kt

A(t)=A
0
e

WhereA(t)isamountofdruginbloodattimetinhours,A
0
istheinitialamountofdrug,
andistherateofdecay(itwillbeanegativenumber)

Youwillhavetofindtheactualvalueofkthatworksforthismodel.

WritedowntheexponentialdecaymodelfortheamountofdruginDotsbloodasa
functionoftime:

-0.0719205181(t)

Model:
1000e


Nowusethatmodeltofillinthefollowingtable:

TIMESINCE
TAKINGTHEDRUG
(HR)

AMOUNTOF
DRUGINHER
BLOOD(MG)

1000

750

562.5

12

421.9

16

316.4

20

237.9

24

178

28

133.5

32

100.1

36

75.1

40

56.3

44

42.2

48

31.7

52

23.8

56

17.8

60

13.4

64

10

68

7.5

10.)Interprettheparametersofthisexponentialmodelintermsofthecontextofthe
problem.

ThismodelismuchmoreeasiertofindtheamountofdruginDotssystem
foracertaintime.

11.)Compareyourvalueswiththeestimatedvaluesinthemodel.Howclosewere
they?Whymighttheybedifferent?

Thevaluesforbothtableswereverysimilarbutthesecondtableismore
accuratethanthefirstbecausethefirsttableisjustanapproximation.

12.)Useagraphingutilitytographtheoriginaldataalongwithagraphofthemodelon
thesamesetofaxes.Copyandpastegraphintothisdocument.

13.)Wereyouexpectingahorizontalasymptote?Whatmightthatmeaninthecontext
oftheproblem?

Yes,sincethegraphwassofamiliartothefirstiknewtherewouldbea
horizontalasymptoteonthexaxis.

14.)Usingyourmodel,howmuchdrugisinhersystem17hoursaftertakingthedrug?

294.426Milligrams.

15.)Usingyourmodel,howlongwillittakeforexactlyonehalfofthedrugtoremainin
hersystem?

Itwillreach500milligramsatapprox.9.638hours

16.)Usingthismodel,howlongwillittakefor0.1mgofthedrugtoremaininher
system?

Themodelwillreach0.1milligramafterapprox.128.06hours

17.)Doyouthinkthecontinuousdecaymodelismoreaccurateforpredictingthe
amountofdruginherblood?Why?Orwhynot?

Yes,Ithinkthatthecontinuousdecaymodelismoreaccuratebecauseit
usestheexactrateofdecayforthedrug.

18.)Whatotherfactorsshouldbeconsideredincomingupwithamorerealisticmodel?

Therearemanyfactorstotakeintoconsiderationthatcouldaltertherate
ofdecay.Eventheslightestthingsliketakingdifferentkindsofmedication
andfluidscouldchangethemodel.