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Chapter 2

Figure 2.1 The odds ratio (& 95% CI) of CHD for MTHFR 677 TT vs CC genotype by region of origin.
The size of the squares is inversely proportional to the variance of the log OR and the horizontal lines
represent the 95% CI. Studies are ordered by the number of cases in each region. The combined OR
and the sub-totals for each region and their 95% CI are indicated by the diamonds.

34

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