Beruflich Dokumente
Kultur Dokumente
12. A 30-year-old female having habit of keeping her contact lenses in tap water. She noticed
deterioration of vision and visited an ophthalmologist who diagnosed her with severe retinitis.
Culture of the tap water as well as vitreous fluid would most likely reveal:
a.
Trophozoites with blunt pseudopodia
b.
Trophozoites with lobopodia
c.
Trophozoites with thorn like pseudopodia
d.
Trophozoites with finger like pseudopodia
23. The current vaccination (since April 2016) for polio under national immunization programme is(a) Three doses of trivalent OPV 6,10 and 14 weeks plus one dose of IPV at 14 week
(b) Three doses of IPV 6,10 and 14 weeks plus one dose of bivalent OPV at 14 week
Streptococcus pneumoniae
Group B streptococcus
Group A streptococcus
Enterococcus
41. Which of the following is the second most common cause of pediatric gastroenteritis? Unlike other
similar viruses of this family, this virus causes only gastroenteritis.
a.
b.
c.
d.
Rotavirus
Adenovirus 40/41
Norwalk virus
Astrovirus
42. A 6-year-old girl presents to the clinic with scaly patches on the scalp. Primary culture of the skin
and hair revealed spindle shaped macrocondia. A few weeks later, she returned and was found to
have inflammatory lesions. The hair fluoresced under Woods light and primary smears of skin and
hair contained septate hyphae. On speaking with the parents, it was discovered that there were
several pets in the household. Which of the following is the most likely agent?
a.
b.
c.
d.
Microsporum canis
Trichophyton tonsurans
Trichophyton rubrum
Epidermophyton floccosum
43. A sputum sample was brought to the laboratory for analysis. Gram stain revealed the following: rare
epithelial cells, 25 polymorphonuclear leukocytes per high-power field, and pleomorphic Gramnegative rods. As the laboratory consultant, which of the following interpretations should you make?
a.
b.
c.
d.
44. A patient with a peptic ulcer was admitted to the hospital and a gastric biopsy was performed. The
tissue was cultured on chocolate agar incubated in a microaerophilic environment at 37 C for 5 to 7
days. At 5 days of incubation, colonies appeared on the plate and were curved, Gram negative rods,
oxidase-positive. The most likely identity of this organism is
a.
b.
c.
d.
Campylobacter jejuni
Vibrio parahaemolyticus
Haemophilus influenzae
Helicobacter pylori
d.
Sputum
47. Trypanosoma cruzi initially causes chagoma. In the chronic stage of the disease, the main lesions are
often observed in which of the following system:
a. Spleen and pancreas
b. Heart and digestive tract
c. Liver and spleen
d. Digestive tract and respiratory tract
48. A patient with history traveling to Sudan in central Africa. He presents with marked splenic
enlargement, nonspecific hypergammaglobulinemia, and a negative leishmanin skin test. However,
there is a mild fever twice daily and a darkening of his skin over the temples. Your tentative diagnosis
is:
a.
b.
c.
d.
Malaria
Cutaneous leishmaniasis
Visceral leishmaniasis
Trypanosomiasis
49. The diagnostic characteristics of Plasmodium falciparum - best described by which one of the
following statements?
a. A period of 96 h is required for the development of the mature schizont, which resembles a rosette with
only 18 to 20 oval merozoites
b. An important diagnostic feature is the irregular appearance of the edges of the infected red blood cell
c. Only ring forms of early trophozoites and the gametocytes are seen in the peripheral blood
d. Schizonts are usually found in peripheral smear
50. A woman with recent history of travel to malaria endemic area, complains of having paroxysmal
attacks of chills, fever, and sweating; these attacks last 6 days, that recurs every 36 to 48 h.
Examination of a stained peripheral smear reveals band shaped forms within red blood cells. The
infecting organism most likely is:
a. Plasmodium falciparum
b. Plasmodium vivax
c. Plasmodium malariae
d. Plasmodium ovale
51. The severity of infection with Plasmodium falciparum as compared with the other three forms of
malaria is due to one of the following reasons:
a.
b.
c.
d.
52.
a.
b.
c.
d.
Human infection with Taenia saginata, usually is less serious than infection with T. solium, because:
Larval invasion does not occur in beef tapeworm infection
Toxic by-products are not given off by the adult beef tapeworm
The adult beef tapeworms are smaller
Beef tapeworm eggs cause less irritation of the mucosa of the digestive tract
53. Examination of patients stool reveals small structures resembling rice grains; microscopic examination
shows these to be proglottids. The most likely organism in this patients stool is:
a.
b.
c.
d.
Enterobius vermicularis
Ascaris lumbricoides
Necator americanus
T. saginata
54. A pork-eating village, reported to be suffering from an epidemic outbreak of epileptiform seizures. You
have been sent to investigate. One of the first things you should investigate is:
a.
b.
c.
d.
55. 32 year male patient with history consumption of raw fish daily for 2 weeks. After 5 months, he had a
routine physical examination and was found to be anemic. His vitamin B12 levels were below normal. The
most likely cause of her vitamin B12 deficiency anemia is:
a. Excessive consumption of ice-cold vodka
b. Infection with parvovirus B 19
c. Infection with D. latum
d. Infection with Yersinia
56.
a.
b.
c.
d.
57. The egg which of the following parasites consist of polar filaments arising from either end of the
embryophore:
a. Taenia saginata
b. Taenia solium
c. Echinococcus granulosis
d. Hymenolepis nana
58.
a.
b.
c.
d.
Which of the following organisms penetrates skin, and has a large lateral spine on its eggs?
Paragonimus
S. mansoni
Schistosoma japonicum
Schistosoma haematobium
59. Which of the following organisms may be ingested with raw fish, affects the liver, and has an
operculated egg?
a.
Paragonimus
b.
Clonorchis
c.
S. mansoni
d.
S. japonicum
60. Painless termianal hematuria is seen as one of the manifestations in the infection caused by:
a.
Schistosoma japonicum
b.
Schistosoma mansoni
c.
Schistosoma haematobium
d.
Schistosoma falciparum
61. A 57-year-old man arrives at the emergency room complaining of weakness, fatigue, and intermittent
fever that has recurred for several weeks. The patient had a cardiac valvular prosthesis implanted
five years earlier. Physical examination reveals petechiae (pinpoint, nonraised, purplish-red spots
caused by intradermal hemorrhage) on the chest and stomach. Blood cultures grew catalase-positive,
coagulase-negative, cocci. The gram-positive organisms failed to ferment mannitol, and their growth
was inhibited by novobiocin. What is the most likely infectious agent?
a. Staphylococcus aureus
b. Staphylococcus epidermidis
c. Staphylococcus saprophyticus
d. Streptococcus pneumoniae
62. A 32-year-old woman became ill four days after the onset of her menstrual period. She presented in
the emergency room with fever (104F; normal = 98.6F), elevated white blood cell count
(16,000/mm3; normal = 4,000 to 10,000/mm3), and a rash on her trunk and extremities. She
complained of fatigue, vomiting, and diarrhea. She had recently eaten at a fast-food restaurant, but
otherwise had prepared all her meals at home. The patient described most likely has:
a. staphylococcal food poisoning.
b. scalded skin syndrome.
c. chickenpox.
d. toxic shock syndrome.
63. Community acquired MRSA differs from hospital acquired MRSA in all the features except:
a.
b.
c.
CA-MRSA strains have been associated with type4 SCC MEC (Staphylococcal cassette
chromosomes).
Cholera toxin
b.
Botulinum toxin C
c.
Diphtheria toxin
d.
67. A 55-year-old man was admitted to a local hospital with fever and chills. The patient was HIV
positive and had received multiple courses of antibiotics. Blood cultures grew gram-positive cocci,
which tested positive with Group D streptococcal antisera. The isolate was resistant to penicillin and
vancomycin and was found to ferment arabinose. Which one of the following is the most likely
pathogen?
a. Streptococcus pneumoniae
b.
c.
d.
Enterococcus faecium
Streptococcus agalactiae
Enterococcus faecalis
68. Which among the following statements about Enterococcus species are not true?
a. Enterococcus faecium is usually much more antibiotic resistant than E.faecalis
b. Enterococcus faecalis causes 85-90% of the clinical infections.
c. VanA phenotype is manifested by inducible high level resistance to both vancomycin and
teicoplanin.
d. VanC phenotype is plasmid mediated.
69. A gram-negative diplococcus was isolated from a chocolate agar culture of a cerebrospinal fluid
sample. Which one of the following tests or observations would be most informative in identifying the
organism as N. meningitidis?
a. Appearance of colonies
b. Growth on Thayer-Martin medium
c. Direct oxidase test on CSF
d. Positive oxidase test and ability of culture isolate to ferment glucose and maltose
70. Neisseria bacterimia is favoured by complement deficiency of
a. C1 to C2
b. C1 to C3
c. C1 to C4
d. C5 to C8
71. Which of the following statements about diphtheria is FALSEa. Immunity to diphtheria depends circulating antitoxin >0.01 IU/ml
b. Vaccinated children can get skin lesion due to cutaneous diphtheria
c. Toxin is regulated by iron conc.
d. Fragment A of the toxin is responsible for attachment to host cells
72. Earliest growth of diphtheria bacilli can be detected of
a. Blood agar
b. Potassium tellurite agar
c. Loeffler serum slope
d. Nutrient agar
73. Which of the following is a tripartite toxin?
a. Diphtheria toxin
b. Anthrax toxin
c. Botulinum toxin
d. Cholera toxin
74. The entire following are true of Botulism. Except;
a. It causes a symmetric descending paralysis
b. Botulinum toxin acts on GABA neurotransmitter.
c. All produce neurotoxin except C2 which shows enterotoxic activity
d. Produces constipation
75. All are correct regarding Widal test, except ?
a. Baseline titres differ depending on the endemicity of the disease
b. Single test of high titre is not enough for conclusive diagnosis
b.
c.
d.
77. E.coli O104 strain can cause hemorrhagic uremic syndrome and had recently caused outbreak in
Germany in 2013. It belongs to which Diarrheagenic E.coli?
a. EPEC
b. EHEC
c. EAEC
d. EIEC
78. Vibrio vulnificus, which is a marine Vibrio of medical importance, mostly found in the in temperate
and tropical climates is best characterized as
a.
b.
Halophilic, lactosefermenter
c.
d.
79. An elderly man, hospitalized and recovering from cardiac bypass surgery, develops pneumonia.
Sputum culture reveals a gram-negative rod that produces a green pigment but does not ferment
carbohydrates. The most likely organism is
a. Serratia species
b. Proteus species
c. Enterobacter species
d. Pseudomonas aeruginosa
80. A young boy had a flea bite while working in a wheat grain godown. After 5 days he developed fever
and had axillary lymphadenopathy. A smear was sent to the laboratory to perform a specific
staining. Which one of the following staining method would help in the identification of the
suspected pathogen:
a.Albert staining.
b.Zeihl Neelson staining
c.Mc Fadyean staining
d.Wayson staining
81. Biotypes of H influenza most frequently responsible for meningitis
a. 5
b. 3
c. 6
d. 1
82. Which of the following test would you recommend for a farmer suffering from Fever of unknown
origin who raises goats and had a history of drinking raw milk ?
a. Standard agglutination test
b. Weil Felix test
c. Widal test
d.
For sputum to be positive, minimum bacilli load should be > 104 /ml of sputum
b.
c.
d.
86. Which one of the following statement is true regarding pathogenicity of Mycobacteria speciesa.
b.
c.
d.
RPR/FTA-Abs
c.
d.
VDRL/RPR
89. A 32-year old swimmer, presented with history of high grade fever for 7 days and altered sensorium
for 2 days. On examination, he was comatosed and had sub conjunctival hemorrhage. Urgent
investigations showed a haemoglobin of 9 gm/dl, serum bilirubin 10 mg/dl and urea 88 mg/dl.
Peripheral blood smear was negative for malarial parasite. What is the most likely diagnosis ?
a. Brucellosis
b. Leptospirosis
High OX-2
b.
High OX-19
c.
High OX-K
d.
93. The following biochemical and cultural property belong to which bacteria?
a.
b.
c.
d.
94.
Escherichia coli
Klebsiella pneumoniae
Proteus mirabilis
Shigella flexneri
Gram stain of CSF a suspected case of pyogenic meningitis is depicted in picture. Which is
correct about this organism?
a.
b.
c.
d.
a.
b.
c.
d.
96. The electron micrograph of the following picture belongs to which virus?
a.
b.
c.
d.
Coronavirus
Rotavirus
Pox virus
Astrovirus
97. The following dermatophyte given in picture infects which part of body?
a. Skin only
b. Skin and hair
c. Skin and nail
d. Skin, hair and nail
98. Indentify the fungus?
a. Aspergillus fumigatus
b. Aspergillus flavus
c. Aspergillus niger
d. Aspergillus nidulans
99. Which is correct about the following malaria parasite given in the picture?
100.
a.
b.
c.
d.