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afterusingitoveralongperiodoftime.
Donotstopusingbaclofenwithoutfirsttalkingtoyourdoctor.Youmayneedtouselessandless
beforeyoustopthemedicationcompletely.Usingbaclofenmayincreaseyourriskofdevelopingan
ovariancyst.Talkwithyourdoctoraboutyourspecificrisk.
kidneydisease;
epilepsyorotherseizuredisorder;or
ahistoryofstrokeorbloodclots.
Usingbaclofenmayincreaseyourriskofdevelopinganovariancyst
What is baclofen?
Baclofenisamusclerelaxerandanantispasticagent.
Baclofenisusedtotreatmusclesymptomscausedbymultiplesclerosis,includingspasm,pain,and
stiffness.
Baclofenmayalsobeusedforpurposesnotlistedinthismedicationguide.
Important information
Baclofenmayimpairyourthinkingorreactions.Becarefulifyoudriveordoanythingthatrequires
youtobealert.Drinkingalcoholcanincreasecertainsideeffectsofbaclofen.Donotusebaclofenata
timewhenmuscletoneisneededtoassuresafebalanceandmovementforcertainactivities.Insome
situations,itmayendangeryourphysicalsafetytobeinastateofreducedmuscletone.
Measureranitidineliquidwithaspecialdosemeasuringspoonorcup,notaregulartablespoon.Ifyou
donothaveadosemeasuringdevice,askyourpharmacistforone.
Itmaytakeupto8weeksbeforeyourulcerheals.Keepusingthemedicationasdirectedandtellyour
doctorifyoursymptomsdonotimproveafter6weeksoftreatment.
Thismedicationcancauseunusualresultswithcertainmedicaltests.Tellanydoctorwhotreatsyou
thatyouareusingranitidine.
Storeranitidineatroomtemperatureawayfrommoisture,heat,andlight.
Seealso:DosageInformation(inmoredetail)
kidney disease;
liver disease; or
porphyria.
FDApregnancycategoryB.Ranitidineisnotexpectedtobeharmfultoanunbornbaby.Tellyour
doctorifyouarepregnantorplantobecomepregnantduringtreatment.Ranitidinepassesintobreast
milk.Donottakeranitidinewithouttellingyourdoctorifyouarebreastfeedingababy.
Seealso:Pregnancyandbreastfeedingwarnings(inmoredetail)
Usingranitidinemayincreaseyourriskofdevelopingpneumonia.Symptomsofpneumoniainclude
chestpain,fever,feelingshortofbreath,andcoughingupgreenoryellowmucus.Talkwithyour
doctoraboutyourspecificriskofdevelopingpneumonia.
Donotusethismedicationifyouareallergictoranitidine.
Slideshow
The Dangers Of DVT: Don't Ignore The Signs
Askadoctororpharmacistifitissafeforyoutotakethismedicineifyouhavekidneydisease,liver
disease,orporphyria.
Heartburnisoftenconfusedwiththefirstsymptomsofaheartattack.Seekemergencymedical
attentionifyouhavechestpainorheavyfeeling,painspreadingtothearmorshoulder,nausea,
sweating,andageneralillfeeling.
Ranitidinegranulesandeffervescenttabletsmustbedissolvedinwaterbeforeyoutakethem.Your
doctormayrecommendanantacidtohelprelievepain.Carefullyfollowyourdoctor'sdirectionsabout
thetypeofantacidtouse,andwhentouseit.Avoiddrinkingalcohol.Itcanincreasetheriskof
damagetoyourstomach.Itmaytakeupto8weeksofusingthismedicine
What is ranitidine?
Ranitidineisinagroupofdrugscalledhistamine2blockers.Ranitidineworksbyreducingtheamount
ofacidyourstomachproduces.
Ranitidineisusedtotreatandpreventulcersinthestomachandintestines.Italsotreatsconditionsin
whichthestomachproducestoomuchacid,suchasZollingerEllisonsyndrome.Ranitidinealsotreats
gastroesophagealrefluxdisease(GERD)andotherconditionsinwhichacidbacksupfromthestomach
intotheesophagus,causingheartburn.
Before she could walk Munrize danced to her rhythm. When she took her first
step her second step was a dance. By the age of three, Munrize was the featured
dancer for the harvest festival. Her brown legs moved in perfect rhythm to the
beat of her brothers drums while her long be
UnitedStates.78Thesubjectsreceivedpirenzipine0.5%forthefirstweek,1.0%forthesecondweek,
and2.0%foranadditional2weeks.Anotherstudyof49adultmalevolunteersfoundthatpirenzepine
ophthalmicgelat0.5%,1.0%,and2.0%waswelltolerated,producedminimalmydriasis,andtheonly
adverseeventnotedwasatransientunilaterallossofvisualacuityinonepatientwhichrecoveredby
thenextvisit.79Althoughrandomisedclinicaltrialsarecurrentlyinprogress,efficacydataarenotyet
available.
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dosesofatropine(1%atropine)may,however,beassociatedwithanincreasedincidenceandseverity
oflocaleffects(examplesincludemydriasis,photophobia,blurredvision,allergicdermatitis)and
systemiceffects34,68,69;lowerdosesofatropine(0.5%,0.25%,0.1%)werebettertolerated.68Thelong
termsideeffectsofatropineeyedropsinchildrenarerelativelyunknownandtheremaybeariskof
longtermultravioletlightrelatedretinaldamageandcataractformationasaresultofchronicpupillary
dilatation.64
PirenzipineisarelativelyselectiveM1subtypemuscarinicreceptorantagonistandM1receptorsare
foundintheciliaryprocesses.7074Inbothavianandmammalianmodels,pirenzipinehasbeenshownto
blockformdeprivationmyopiaandaxialelongation.7577Thetolerabilityofpirenzipinegelformulation
wastestedinadoublemaskedplacebocontrolledrandomisedclinicaltrialofchildrenaged912years
inthe
Atropinesuppressesgrowthhormonesecretionfromthepituitaryglandwhichcoulddisturbnormal
eyegrowth.57,58
ThefirstreportsofatropinetreatmentformyopiawerebyWellsinthe19thcentury.3In1979,
Bedrossianevaluatedtheeffectof1%atropineointmentinstilledonceatnightinoneeyefor1year
withthefelloweyeasthecontrolinanonrandomisedtrial.After1year,treatmentwasswitchedtothe
felloweye,andthecontroleyesshowedsignificantincreasesintherateofmyopia. 59However,the
felloweyemaynotbesuitableasacontrolastheremaybesystemicresidualeffectsofatropineonthe
felloweye.Severalotherstudieshaveevaluatedtopicalatropinetherapybutunfortunatelyhad
sufficientmethodologicalflawstoprecludeanyreliableconclusions.15,16,6067Arangeofconcentrations
(0.1%to1%)ofatropineeyedropsweretestedinthreerandomisedclinicaltrialsofschoolchildrenin
Taiwanandtherateofprogressionofmyopiaintheatropinegroupwassignificantlylowercompared
withthecontrolgroup.34,68,69Higher