B.

4 Glucose tolerance-oral (OGTT) (serum) and IV (IV-GTT)

Child: Depends on the child’s age. Infants normally have lower blood sugar levels (see
Glucose-Fasting Blood Sugar). A child aged 6 or older has results similar to those of the
adult.

Description

A glucose tolerance test (GTT) is done to diagnose diabetes mellitus in persons

having high-normal or slightly elevated blood sugar values. The test may be indicated
when there is a familial history of diabetes, in women having babies weighing 10 lb or
more, in persons having extensive surgery or injury, and in persons with obesity
problems. The test should not be performed if the fasting blood sugar (FBS) is greater
than 200 mg/dl. After the age of 60 years, the glucose level is usually 10 to 30 mg/dl
higher than the “normal range”.

The peak glucose level for the oral GTT (OGTT) is ½ to 1 hour after the ingestion
of 100 g of glucose, and the blood sugar should return to normal range in 3 hours. Blood
samples will be collected at specified times.

The intravenous glucose tolerance test (IV-GTT) is considered by many to be

more sensitive than the oral GTT, because absorption through the gastrointestinal tract is
not involved. The IV-GTT is usually done if the person cannot eat or tolerate the oral
glucose. The blood glucose returns to the normal range in 2 hours. However, the values
for the OGTT and IV-GTT slightly defer, because IV glucose is absorb faster.

Hyperisulinism can be detected with the OGTT. After 1 hour blood glucose level
is usually level than in the FBS test. The person might develop severe hypoglycemic
reactions- there is more insulin being secreted in response to the blood glucose.

Purpose

• To confirm the diagnosis of Diabetes Melllitus

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