VITAMINS

Organic dietary substances essential for promotion of growth

and maintenance of health.
DEFICIENCY MANIFESTATIONS:
• Failure of growth
• Lack of calcification of bones
• Can cause diseases such as Beri-Beri , Pellagra , Scurvy
TYPES OF VITAMINS

• Fat Soluble Vitamins :

Vitamin A: Daily requirement is 5000 I.U(I.U = 0.3ug
• DEFICIENCY MANIFESTATIONS:
- Dryness of Skin
- Night Blindness (Xeropthalmia )
- Keratomalacia(softening of Cornea)
- Keratinization of Skin
• TOXICITY:
- Bony Swelling
- Anorexia
- Dry itching Skin
FAT SOLUBLE VITAMINS
• VITAMIN D : Daily requirement is 400-800 I.U
• DEFICIENCY MANIFESTATIONS :
- Rickets in children and Osteomalacia in adults
- Malformation of Teeth
• TOXICITY :
- Nausea , Vomiting , Polydipsia , Polyuria , Vague Pains
Stuper , Metastatic Cacification in arteries ,heart
Renal tubules and Lungs.
FAT SOLUBLE VITAMINS
• VITAMIN E: Daily requirement 30 mgs
Anti-Sterility and Anti- Abortion Vitamin used in Habitual
and threatened abortions
• VITAMIN K : Daily requirement 5-30mgs

Antihaemorrhagic or Coagulation Vitamin

Deficiency leads to Prolonged Clotting Time

WATER SOLUBLE VITAMINS
• VITAMIN B - COMPLEX :
Vitamin B1 or Thiamine
Vitamin B2 or Riboflavin
Vitamin B6 or Pyridoxine
Vitamin B12 or Cynocobalamine
Nicotinic Acid
Folic Acid
Pantothenic Acid
Inositol
Choline
Biotin
LYSOVIT
LYSOVIT IS A B - COMPLEX AND LYSINE
PREPARATION.

INDICATIONS :

• GROWTH PROMOTING TONIC

• PROMOTES APPETITE
• PREVENTION OF VITAMIN DEFICIENCY
IN CHILDREN
COMPOSITION
EACH 5ml ( ONE TEASPOONFUL ) CONTAINS :
VITAMIN B1 = 4.16 mg
VITAMIN B2 = 1.66 mg
VITAMIN B6 = 1.00 mg
VITAMIN B12= 8.33 mg
NIACINAMIDE= 18.0 mg
CALCIUM d-PANTOTHENATE= 2.5 mg
ASCORBIC ACID = 75.0 mg
INOSITOL = 5.0 mg
LYSINE
MONOHYDROCHLORIDE = 33.33 mg
COMBANTRIN
BRAND NAME : COMBANTRIN
GENERIC NAME : PRRANTEL PAMOATE
• ACTIONS :
COMBANTRIN IS AN ANTHELMINTIC AGENT
EFFECTIVE AGAINST :
- ENTEROBIUS VERMICULARIS
- ASCARIS LUMBRICOIDES
- ANCYLOSTOMA DUODENALE
- NECATOR AMERICANUS
- TRICHOSTROGYLUS COLUBRIFORMIS
- TRICHOSTTRONGYLUS ORIENTALIS
- TRICHURIS TRICHUIRA
MODE OF ACTION

COMBANTRIN EXERCISES A NEUROMUSCULAR

BLOCKING EFFECT ON SUSCEPTIBLE HELMINTHS,
(PARALYSING THE WORMS ) AND BRINGS ABOUT
THEIR EXPULSION WITHOUT PRODUCING
EXCITATION OR STIMULATING MIGRATION OF
WORMS.
COMBANTRIN
• EFFECTIVE AGAINST MATURE AND IMMATURE
WORMS.
• POORLY ABSORBED FROM G.I TRACT
• 50 % OF THE DRUG IS EXCRETED VIA FECES IN
UNCHANGED FORM.
• LESS THAN 7 % IS FOUND IN URINE UNCHANGED
AND IN METABOLITES FORM.
ADVERSE REACTIONS
• ANOREXIA
• ABDOMINAL CRAMPS
• NAUSIA
• VOMITING
• DIARRHEA
• HEADACHE
• DIZZINESS
• INSOMNIA
• RASH
PRECAUTION

• COMBANTRIN SHOULD BE USED WITH CAUTION

IN PATIENTS WITH HEPATIC DYSFUNCTION

• COMBANTRIN HAS NOT BEEN STUDIED IN

PREGNANT PATIENTS SO IT SHOULD NOT BE USED
IN PREGNANCY UNLESS IN THE JUDGEMENT OF THE
PHYSICIAN, IT IS ESSENTIAL FOR THE WELFARE
OF THE PATIENT.
DOSAGE AND
ADMINISTRATION
• 10mg PER KILOGRAM OF BODY WEIGHT AS A
SINGLE DOSE.
6 MONTHS - 2 YEARS = 1/ 2 TAB 1 / 2 TSP

2 YRS - 6 YRS = 1 // 1 //
6 YRS - 12 YRS = 2 // 2 //
OVER 12 YRS = 3 // 3 //
OVER 75 KG WEIGHT = 4 // 4 //
COREX - D COUGH SYRUP
EFFECTIVE IN ALL TYPES OF CONDITIONS WHERE
COUGH IS A TROUBLESOME SYMPTOM.
INDICATIONS :
• SUPPRESSION OF DRY COUGH
• COUGH ASSOCIATED WITH ASTHMA, PNEUMONIA
BRONCHITIS , WHOOPING COUGH AND POST
INFLUENZAL SYNDROME
COMPOSITION(5 ML
CONTAINS )
• DEXTROMETHORPHANE HBR : 10 mg
SAFE AND EFFECTIVE ANTITUSSIVE
• EPHEDRINE HCL : 5 mg
RELIEVES BRONCHOSPASM
• CHLORPHENIRAMINE : 4 mg
CONTROL ALLERGIC COMPONENTS
• SODIUM CITRATE : 150 mg
SOOTHES THE INFLAMMED BRONCHIAL TREE
PROMOTES EXPECTORATION
ACTIONS OF WATER
SOLUBLE VITAMINS
• B1 = FUNCTIONS PRIMARILY AS CO-ENZYME WITH
CO - CARBOXYLASE, IN CARBOHYDRATE
METABOLISM.. D.R. 1 - 15mg
• B2 = FUNCTIONS IN THE TISSUE RESPIRATORY
ENZYME SYSTEM , WHICH IS CONCERNED
WITH THE OXYGEN TRANSPORT. D.R. 0.5-1.5mg
• B6 = SERVES AS A CO - ENZYME IN DE-CARBOXYL-
ATION OF AMINO ACIDS. USED IN TREATMENT
OF PREGNANCY VOMITING AND RADIATION
SICKNESS. D.R. 2mg
WATER SOLUBLE VITAMINS
• B12 = ESSENTIAL FOR NORMAL GROWTH AND
PROPER FORMATION OF BONE MARROW
THUS NORMAL FORMATION OF RBCs. 1-2mcg
• C = NECESSARY FOR FORMATION OF COLLAGEN
AND INTERCELLULAR CEMENT SUBSTANCE
THUS HELPFUL FOR CARTILAGE,BONE,TEETH
AND FOR HEALING OF WOUNDS.D.R 550 -75 mg