ANTIPSYCHOTICS:

SIDE- EFFECTS
G.SONIYA
MSc (N) IYr
TARDIVE DYSKINESIA
TARDIVE DYSKINESIA
• EARLY SIGNS
• Fine wormlike
movements of the
tongue
• Increased blinking
TARDIVE DYSKINESIA
• Involuntary
choreoathletic
movements
affecting face,
tongue, perioral,
buccal and
mzsticatory
muscles
TARDIVE DYSKINESIA
• RABBIT • Tongue
SYNDROME protrusion.
• Unusual mouth
movements such
as smacking lips
or chewing jaw
movements
TARDIVE DYSKINESIA
TARDIVE DYSKINESIA
AKATHISIA- SIGNS & SYMPTOMS
Occurs at 5 to 60 days
after initiation of
treatment.
Walkie- talkie
syndrome.
Restless or inability to
sit still
Excitement
Agitation
Foot tapping
Motoric hyperactivity
AKATHISIA
AKATHISIA
AKATHISIA- Treatment
• Antiparkinsonis
m drugs.
• Trihexyphenidyl
• Propanolol
• Benzodiazipines
• Clonidine
• Changing to
different
neuroleptics.
Oculogyric crisis
Eyes rolling
upward &
unable to move
downward.
Treatment;
i.v.
benzotrophine
mesylate
DYSTONIA
• Acute dystonic
reaction occur
within 5 days of
treatment..
• Muscular
hypertonicity
DYSTONIA
• MUSCULAR
CONTRACTION
DYSTONIA
• Spasm of face, • Involuntary tonic
arms, legs contraction of
muscles of mouth
and torso.

• TREATMENT
Anticholinergic
Antiparkinsonisian
drugs
PSEUDOPARKINSONISM
• Symptoms develop 1
to 5 days after
initiation of treatment.
• Tremors( finger and
hand)
• Shuffling gait
• Drooling
• Rigid mask like face
• Muscular
rigidity(cogwhweel
syndrome)
PSEUDOPARKINSONISM
UTYIL
TREMORS:
PSEUDOPARKI
NSONISM
PSEUDOPARKINSONISM
THANK YOU