Chapter 3,4,5 and 7 Copstead and Banasik

Chapter 4 and 5 Lehne

Study Guide

Please note that this a general guide; you are still responsible for the readings, and
there may be things on the exam not mentioned specifically in the guide.

Expect multiple choice, True and False and matching questions.

Chapter 3
1. Know the functions of the plasma membrane Pg31-61
2. The major function of the organelles
3. Know how a cell conducts cellular metabolism
4. Know how a cell transports small molecules (pumps) and
large molecules (Endocytosis)

Chapter 4
1. Know the characteristics that all cell exhibit to cell injury; Pg 65-82
specifically Hydropic swelling and Intracellular
Accumulations.
2. Know the difference between reversible and irreversible
injury
3. Know the cellular adaptations to injury when presented
with a description.
4. Know the difference between necrosis and gangrene
5. Know the mechanisms of apoptosis

Chapter 5
1. Know what a gene, chromosome, and helix are Pg 86-100
2. Know how a gene prevents defective base pairs from
being sent to the newly synthesized cell.
3. Know the four categories of differentiated cell/tissue types
based on a description

Chapter 7
1. Know the difference between neoplasia, cancer and Pg 129-155
benign growth
2. Know the difference between a proto oncogene and a
tumor suppressor cell
3. Know the definition of metastasis
4. Given a set of staging variables for breast cancer; be able
to state what the prognosis for the individual is.
5. Be able to identify the common effects cancer has on the
body when presented with a description.
6. Identify the tumor suppressor cells and their function.
 Lehne Chap 4 and 5
• Define the difference between Antagonist and Agonist Pg 25 - 55
and what happens at the receptor site.
• Understand the 4 step process of Pharmacokinetics
and the difference from Pharmacodynamics.
• Think of pt. scenarios that might affect the
pharmacokinetics process
• Name and understand the General Properties of drugs
• Define the Therapeutic index, range and half life
• Terms of affinity
• The basic concept of why RN’s need to know about the
CYP 450 system and its isoforms.
• Really understand the basic ideas of each step of
pharmacokinetics.