CH14 Study Questions

Biology, 8e (Campbell)
Chapter 14 Mendel and the Gene Idea

Multiple‐Choice Questions
1) Pea plants were particularly well suited for use in Mendel's breeding experiments for all of
the following reasons except that
A) peas show easily observed variations in a number of characters, such as pea shape and
flower color.
B) it is possible to control matings between different pea plants.
C) it is possible to obtain large numbers of progeny from any given cross.
D) peas have an unusually long generation time.
E) many of the observable characters that vary in pea plants are controlled by single
genes.
Answer: D
Topic: Concept 14.1
Skill: Knowledge/Comprehension
2) What is the difference between a monohybrid cross and a dihybrid cross?

A) A monohybrid cross involves a single parent, whereas a dihybrid cross involves two
parents.
B) A monohybrid cross produces a single progeny, whereas a dihybrid cross produces
two progeny.
C) A dihybrid cross involves organisms that are heterozygous for two characters and a
monohybrid only one.
D) A monohybrid cross is performed for one generation, whereas a dihybrid cross is
performed for two generations.
E) A monohybrid cross results in a 9:3:3:1 ratio whereas a dihybrid cross gives a 3:1 ratio.
Answer: C
Topic: Concept 14.1
3) A cross between homozygous purple‐flowered and homozygous white‐flowered pea plants

results in offspring with purple flowers. This demonstrates
A) the blending model of genetics.
B) true‐breeding.
C) dominance.
D) a dihybrid cross.
E) the mistakes made by Mendel.
Answer: C
Topic: Concept 14.1
1
4) The F1 offspring of Mendel's classic pea cross always looked like one of the two parental
varieties because
A) one phenotype was completely dominant over another.
B) each allele affected phenotypic expression.
C) the traits blended together during fertilization.
D) no genes interacted to produce the parental phenotype.
E) different genes interacted to produce the parental phenotype.
Answer: A
Topic: Concept 14.1
5) What was the most significant conclusion that Gregor Mendel drew from his experiments
with pea plants?
A) There is considerable genetic variation in garden peas.
B) Traits are inherited in discrete units, and are not the results of "blending."
C) Recessive genes occur more frequently in the F1 than do dominant ones.
D) Genes are composed of DNA.
E) An organism that is homozygous for many recessive traits is at a disadvantage.
Answer: B
Topic: Concept 14.1
6) How many unique gametes could be produced through independent assortment by an

individual with the genotype AaBbCCDdEE?
A) 4
B) 8
C) 16
D) 32
E) 64
Answer: B
Topic: Concept 14.1
Skill: Application/Analysis
7) Two plants are crossed, resulting in offspring with a 3:1 ratio for a particular trait. This
suggests
A) that the parents were true‐breeding for contrasting traits.
B) incomplete dominance.
C) that a blending of traits has occurred.
D) that the parents were both heterozygous.
E) that each offspring has the same alleles.
Answer: D
Topic: Concept 14.1
2
8) Two characters that appear in a 9:3:3:1 ratio in the F2 generation should have which of the
following properties?
A) Each of the traits is controlled by single genes.
B) The genes controlling the characters obey the law of independent assortment.
C) Each of the genes controlling the characters has two alleles.
D) Four genes are involved.
E) Sixteen different phenotypes are possible.
Answer: B
Topic: Concept 14.1
9) A sexually reproducing animal has two unlinked genes, one for head shape (H) and one for
tail length (T). Its genotype is HhTt. Which of the following genotypes is possible in a gamete
from this organism?
A) HT
B) Hh
C) HhTt
D) T
E) tt
Answer: A
Topic: Concept 14.1
10) It was important that Mendel examined not just the F1 generation in his breeding
experiments, but the F2 generation as well, because
A) he obtained very few F1 progeny, making statistical analysis difficult.
B) parental traits that were not observed in the F1 reappeared in the F2.
C) analysis of the F1 progeny would have allowed him to discover the law of segregation,
but not the law of independent assortment.
D) the dominant phenotypes were visible in the F2 generation, but not in the F1.
E) many of the F1 progeny died.
Answer: B
Topic: Concept 14.1
Skill: Synthesis/Evaluation
11) When crossing an organism that is homozygous recessive for a single trait with a
heterozygote, what is the chance of producing an offspring with the homozygous recessive
phenotype?
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
Answer: C
Topic: Concept 14.1
3
Use Figure 14.1 and the following description to answer the questions below.
 
In a particular plant, leaf color is controlled by gene locus D. Plants with at least one allele D have dark
green leaves, and plants with the homozygous recessive dd genotype have light green leaves. A true‐
breeding dark‐leaved plant is crossed with a light‐leaved one, and the F1 offspring is allowed to self‐
pollinate. The predicted outcome of the F2 is diagrammed in the Punnett square shown in Figure 14.1,
where 1, 2, 3, and 4 represent the genotypes corresponding to each box within the square. 
Figure 14.1
12) Which of the boxes marked 1‐4 correspond to plants with dark leaves?
A) 1 only
B) 1 and 2
C) 2 and 3
D) 4 only
E) 1, 2, and 3
Answer: E
Topic: Concept 14.1
13) Which of the boxes correspond to plants with a heterozygous genotype?

A) 1
B) 1 and 2
C) 1, 2, and 3
D) 2 and 3
E) 2, 3, and 4
Answer: D
Topic: Concept 14.1
14) Which of the plants will be true‐breeding?

A) 1 and 4
B) 2 and 3
C) 1—4
D) 1 only
E) None
Answer: A
Topic: Concept 14.1
4
15) Mendel accounted for the observation that traits which had disappeared in the F1 generation
reappeared in the F2 generation by proposing that
A) new mutations were frequently generated in the F2 progeny, "reinventing" traits that
had been lost in the F1.
B) the mechanism controlling the appearance of traits was different between the F1 and
the F2 plants.
C) traits can be dominant or recessive, and the recessive traits were obscured by the
dominant ones in the F1.
D) the traits were lost in the F1 due to blending of the parental traits.
E) members of the F1 generation had only one allele for each character, but members of
the F2 had two alleles for each character.
Answer: C
Topic: Concept 14.1
16) Which of the following about the law of segregation is false?

A) It states that each of two alleles for a given trait segregate into different gametes.
B) It can be explained by the segregation of homologous chromosomes during meiosis.
C) It can account for the 3:1 ratio seen in the F2 generation of Mendel's crosses.
D) It can be used to predict the likelihood of transmission of certain genetic diseases
within families.
E) It is a method that can be used to determine the number of chromosomes in a plant.
Answer: E
Topic: Concept 14.1
17) The fact that all seven of the pea plant traits studied by Mendel obeyed the principle of
independent assortment most probably indicates which of the following?
A) None of the traits obeyed the law of segregation.
B) The diploid number of chromosomes in the pea plants was 7.
C) All of the genes controlling the traits were located on the same chromosome.
D) All of the genes controlling the traits behaved as if they were on different
chromosomes.
E) The formation of gametes in plants occurs by mitosis only.
Answer: D
Topic: Concept 14.1
18) Mendel was able to draw his ideas of segregation and independent assortment because of
the influence of which of the following?
A) His reading and discussion of Darwin's Origin of Species
B) The understanding of particulate inheritance he learned from renowned scientists of
his time
C) His discussions of heredity with his colleagues at major universities
D) His reading of the scientific literature current in the field
E) His experiments with the breeding of plants such as peas
Answer: E
Topic: Concept 14.1
19) Mendel's observation of the segregation of alleles in gamete formation has its basis in which
of the following phases of cell division?
A) Prophase I of meiosis
B) Prophase II of meiosis
C) Metaphase I of meiosis
D) Anaphase I of meiosis
E) Anaphase of mitosis
Answer: D
Topic: Concept 14.1
5
20) Mendel's second law of independent assortment has its basis in which of the following
events of meiosis I?
A) Synapsis of homologous chromosomes
B) Crossing over
C) Alignment of tetrads at the equator
D) Separation of homologs at anaphase
E) Separation of cells at telophase
Answer: C
Topic: Concept 14.1
21) Black fur in mice (B) is dominant to brown fur (b). Short tails (T) are dominant to long tails
(t). What fraction of the progeny of the cross BbTt × BBtt will have black fur and long tails?
A) 1/16
B) 3/16
C) 3/8
D) 1/2
E) 9/16
Answer: D
Topic: Concept 14.2
22) In certain plants, tall is dominant to short. If a heterozygous plant is crossed with a
homozygous tall plant, what is the probability that the offspring will be short?
A) 1
B) 1/2
C) 1/4
D) 1/6
E) 0
Answer: B
Topic: Concept 14.2
6
23) Two true‐breeding stocks of pea plants are crossed. One parent has red, axial flowers and
the other has white, terminal flowers; all F1 individuals have red, axial flowers. The genes
for flower color and location assort independently. If 1,000 F2 offspring resulted from the
cross, approximately how many of them would you expect to have red, terminal flowers?
A) 65
B) 190
C) 250
D) 565
E) 750
Answer: B
Topic: Concept 14.2
24) In a cross AaBbCc × AaBbCc, what is the probability of producing the genotype AABBCC?
A) 1/4
B) 1/8
C) 1/16
D) 1/32
E) 1/64
Answer: E
Topic: Concept 14.2
25) Given the parents AABBCc × AabbCc, assume simple dominance and independent
assortment. What proportion of the progeny will be expected to phenotypically resemble the
first parent?
A) 1/4
B) 1/8
C) 3/4
D) 3/8
E) 1
Answer: C
Topic: Concept 14.2
Use the following information to answer the questions below.

 
Labrador retrievers are black, brown, or yellow. In a cross of a black female with a brown male, results
can be either all black puppies, 1/2 black to 1/2 brown puppies, or 3/4 black to 1/4 yellow puppies.
26) These results indicate which of the following?

A) Brown is dominant to black.
B) Black is dominant to brown and to yellow.
C) Yellow is dominant to black.
D) There is incomplete dominance.
E) Epistasis is involved.
Answer: E
Topic: Concept 14.2
7
27) How many genes must be responsible for these coat colors in Labrador retrievers?
A) 1
B) 2
C) 3
D) 4
Answer: B
Topic: Concept 14.2
28) In one type cross of black × black, the results were as follows: 
  9/16 black 
  4/16 yellow 
  3/16 brown 
The genotype aabb must result in which of the following?
A) Black
B) Brown
C) Yellow
D) A lethal result
Answer: C
Topic: Concept 14.2

 
Radish flowers may be red, purple, or white. A cross between a red‐flowered plant and a white‐flowered
plant yields all‐purple offspring. The part of the radish we eat may be oval or long, with long being the
dominant characteristic.
29) If true‐breeding red long radishes are crossed with true breeding white oval radishes, the F1
will be expected to be which of the following?
A) Red and long
B) Red and oval
C) White and long
D) Purple and long
E) Purple and oval
Answer: D
Topic: Concept 14.2
30) In the F2 generation of the above cross, which of the following phenotypic ratios would be
expected?
A) 9:3:3:1
B) 9:4:3
C) 1:1:1:1
D) 1:1:1:1:1:1
E) 6:3:3:2:1:1
Answer: E
Topic: Concept 14.2
31) Drosophila (fruit flies) usually have long wings (+) but mutations in two different genes can
result in bent wings (bt) or vestigial wings (vg). If a homozygous bent wing fly is mated with
a homozygous vestigial wing fly, which of the following offspring would you expect?
A) All +bt +vg heterozygotes
B) 1/2 bent and 1/2 vestigial flies
C) All homozygous + flies
D) 3/4 bent to 1/4 vestigial ratio
E) 1/2 bent and vestigial to 1/2 normal
Answer: A
Topic: Concept 14.2
8
32) The flower color trait in radishes is an example of which of the following?
A) A multiple allelic system
B) Sex linkage
C) Codominance
D) Incomplete dominance
E) Epistasis
Answer: D
Topic: Concept 14.3
33) A 1:2:1 phenotypic ratio in the F2 generation of a monohybrid cross is a sign of

A) complete dominance.
B) multiple alleles.
C) incomplete dominance.
D) polygenic inheritance.
E) pleiotropy.
Answer: C
Topic: Concept 14.3
34) In snapdragons, heterozygotes for one of the genes have pink flowers, whereas homozygotes
have red or white flowers. When plants with red flowers are crossed with plants with white
flowers, what proportion of the offspring will have pink flowers?
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
Answer: E
Topic: Concept 14.3
9
35) Tallness (T) in snapdragons is dominant to dwarfness (t), while red (R) flower color is
dominant to white (r). The heterozygous condition results in pink (Rr) flower color. A dwarf,
red snapdragon is crossed with a plant homozygous for tallness and white flowers. What are
the genotype and phenotype of the F1 individuals?
A) ttRr–dwarf and pink
B) ttrr–dwarf and white
C) TtRr–tall and red
D) TtRr–tall and pink
E) TTRR–tall and red
Answer: D
Topic: Concept 14.3
36) Skin color in a certain species of fish is inherited via a single gene with four different alleles.
How many different types of gametes would be possible in this system?
A) 1
B) 2
C) 4
D) 8
E) 16
Answer: C
Topic: Concept 14.3
37) In cattle, roan coat color (mixed red and white hairs) occurs in the heterozygous (Rr)
offspring of red (RR) and white (rr) homozygotes. Which of the following crosses would
produce offspring in the ratio of 1 red : 2 roan : 1 white?
A) red × white
B) roan × roan
C) white × roan
D) red × roan
E) The answer cannot be determined from the information provided.
Answer: B
Topic: Concept 14.3
10
Refer to the following to answer the questions below.
 
Gene S controls the sharpness of spines in a type of cactus. Cactuses with the dominant allele, S, have
sharp spines, whereas homozygous recessive ss cactuses have dull spines. At the same time, a second
gene, N, determines whether cactuses have spines. Homozygous recessive nn cactuses have no spines at
all.
38) The relationship between genes S and N is an example of

A) incomplete dominance.
B) epistasis.
C) complete dominance.
D) pleiotropy.
E) codominance.
Answer: B
Topic: Concept 14.3
39) A cross between a true‐breeding sharp‐spined cactus and a spineless cactus would produce
A) all sharp‐spined progeny.
B) 50% sharp‐spined, 50% dull‐spined progeny.
C) 25% sharp‐spined, 50% dull‐spined, 25% spineless progeny
D) all spineless progeny.
E) It is impossible to determine the phenotypes of the progeny.
Answer: A
Topic: Concept 14.3
40) If doubly heterozygous SsNn cactuses were allowed to self‐pollinate, the F2 would segregate
in which of the following ratios?
A) 3 sharp‐spined : 1 spineless
B) 1 sharp‐spined : 2 dull‐spined : 1 spineless
C) 1 sharp spined : 1 dull‐spined : 1 spineless
D) 1 sharp‐spined : 1 dull‐spined
E) 9 sharp‐spined : 3 dull‐spined : 4 spineless
Answer: E
Topic: Concept 14.3
11
Use the information given here to answer the following questions.
 
Feather color in budgies is determined by two different genes Y and B, one for pigment on the outside
and one for the inside of the feather. YYBB, YyBB, or YYBb is green; yyBB or yyBb is blue; YYbb or Yybb is
yellow; and yybb is white.
41) A blue budgie is crossed with a white budgie. Which of the following results is not possible?
A) Green offspring only
B) Yellow offspring only
C) Blue offspring only
D) Green and yellow offspring
E) a 9:3:3:1 ratio
Answer: D
Topic: Concept 14.3
42) Two blue budgies were crossed. Over the years, they produced 22 offspring, 5 of which were
white. What are the most likely genotypes for the two blue budgies?
A) yyBB and yyBB
B) yyBB and yyBb
C) yyBb and yyBb
D) yyBB and yybb
E) yyBb and yybb
Answer: C
Topic: Concept 14.3

 
A woman who has blood type A positive has a daughter who is type O positive and a son who is type B
negative. Rh positive is a trait that shows simple dominance over Rh negative and is designated by the
alleles R and r, respectively. A third gene for the MN blood group has codominant alleles M and N.
43) Which of the following is a possible partial genotype for the son?
A) IBIB
B) IBIA
C) ii
D) IBi
E) IAIA
Answer: D
Topic: Concept 14.3
12
44) Which of the following is a possible genotype for the mother?
A) IAIA
B) IBIB
C) ii
D) IAi
E) IAIB
Answer: D
Topic: Concept 14.3
45) Which of the following is a possible phenotype for the father?

A) A negative
B) O negative
C) B positive
D) AB negative
E) Impossible to determine
Answer: C
Topic: Concept 14.3
46) Which of the following is the probable genotype for the mother?
A) IAIARR
B) IAIARr
C) IAirr
D) IAiRr
E) IAiRR
Answer: D
Topic: Concept 14.3, Concept 14.4
47) If both children are of blood group MM, which of the following is possible?
A) Each parent is either M or MN.
B) Each parent must be type M.
C) Both children are heterozygous for this gene.
D) Neither parent can have the N allele.
E) The MN blood group is recessive to the ABO blood group.
Answer: A
Topic: Concept 14.3
48) Which describes the ability of a single gene to have multiple phenotypic effects?
A) Incomplete dominance
B) Multiple alleles
C) Pleiotropy
D) Epistasis
Answer: C
Topic: Concept 14.3
13
49) Which describes the ABO blood group system?
B) Multiple alleles
C) Pleiotropy
D) Epistasis
Answer: B
Topic: Concept 14.3
50) Which of the following terms best describes when the phenotype of the heterozygote differs
from the phenotypes of both homozygotes?
B) Multiple alleles
C) Pleiotropy
D) Epistasis
Answer: A
Topic: Concept 14.3
51) Cystic fibrosis affects the lungs, the pancreas, the digestive system, and other organs,
resulting in symptoms ranging from breathing difficulties to recurrent infections. Which of
the following terms best describes this?
B) Multiple alleles
C) Pleiotropy
D) Epistasis
Answer: C
Topic: Concept 14.3
52) Which of the following is an example of polygenic inheritance?

A) Pink flowers in snapdragons
B) The ABO blood groups in humans
C) Huntington's disease in humans
D) White and purple flower color in peas
E) Skin pigmentation in humans
Answer: E
Topic: Concept 14.3
53) Hydrangea plants of the same genotype are planted in a large flower garden. Some of the
plants produce blue flowers and others pink flowers. This can be best explained by which of
the following?
A) Environmental factors such as soil pH
B) The allele for blue hydrangea being completely dominant
C) The alleles being codominant
D) The fact that a mutation has occurred
E) Acknowledging that multiple alleles are involved
Answer: A
Topic: Concept 14.3
54) Which of the following provides an example of epistasis?

A) Recessive genotypes for each of two genes (aabb) results in an albino corn snake.
B) The allele b17 produces a dominant phenotype, although b1 through b16 do not.
C) In rabbits and many other mammals, one genotype (cc) prevents any fur color from
developing.
D) In Drosophila (fruit flies), white eyes can be due to an X‐linked gene or to a combination
of other genes.
Answer: C
Topic: Concept 14.3
14
55) Most genes have many more than two alleles. However, which of the following is also true?
A) At least one allele for a gene always produces a dominant phenotype.
B) Most of the alleles will never be found in a live‐born organism.
C) All of the alleles but one will produce harmful effects if homozygous.
D) There may still be only two phenotypes for the trait.
E) More than two alleles in a genotype is lethal.
Answer: D
Topic: Concept 14.3
56) Huntington's disease is a dominant condition with late age of onset in humans. If one parent
has the disease, what is the probability that his or her child will have the disease?
A) 1
B) 3/4
C) 1/2
D) 1/4
E) 0
Answer: C
Topic: Concept 14.4
57) A woman has six sons. The chance that her next child will be a daughter is
A) 1.
B) 0.
C) 1/2.
D) 1/6.
E) 5/6.
Answer: C
Topic: Concept 14.4
15
The following questions refer to the pedigree chart in Figure 14.2 for a family, some of whose members exhibit the
dominant trait, wooly hair. Affected individuals are indicated by an open square or circle. 
Figure 14.2
58) What is the genotype of individual II‐5?

A) WW
B) Ww
C) ww
D) WW or ww
E) ww or Ww
Answer: C
Topic: Concept 14.4
59) What is the likelihood that the progeny of IV‐3 and IV‐4 will have wooly hair?
A) 0%
B) 25%
C) 50%
D) 75%
E) 100%
Answer: C
Topic: Concept 14.4
60) What is the probability that individual III‐1 is Ww?

A) 3/4
B) 1/4
C) 2/4
D) 2/3
E) 1
Answer: E
Topic: Concept 14.4
16
61) People with sickle‐cell trait
A) are heterozygous for the sickle‐cell allele.
B) are usually healthy.
C) have increased resistance to malaria.
D) produce normal and abnormal hemoglobin.
E) All of the above
Answer: E
Topic: Concept 14.4
62) When a disease is said to have a multifactorial basis, it means that

A) both genetic and environmental factors contribute to the disease.
B) it is caused by a gene with a large number of alleles.
C) it affects a large number of people.
D) it has many different symptoms.
E) it tends to skip a generation.
Answer: A
Topic: Concept 14.4
63) An ideal procedure for fetal testing in humans would have which of the following features?
A) Lowest risk procedure that would provide the most reliable information
B) The procedure that can test for the greatest number of traits at once
C) A procedure that provides a 3D image of the fetus
D) The procedure that can be performed at the earliest time in the pregnancy
E) A procedure that could test for the carrier status of the fetus
Answer: A
Topic: Concept 14.4
64) A scientist discovers a DNA‐based test for the allele of a particular gene. This and only this
allele, if homozygous, produces an effect that results in death at or about the time of birth.
Of the following, which is the best use of this discovery?
A) To screen all newborns of an at‐risk population
B) To design a test for identifying heterozygous carriers of the allele
C) To introduce a normal allele into deficient newborns
D) To follow the segregation of the allele during meiosis
E) To test school‐age children for the disorder
Answer: B
Topic: Concept 14.4
17
65) An obstetrician knows that one of her patients is a pregnant woman whose fetus is at risk for
a serious disorder that is detectable biochemically in fetal cells. The obstetrician would most
reasonably offer which of the following procedures to her patient?
A) CVS
B) Ultrasound imaging
C) Amniocentesis
D) Fetoscopy
E) X‐ray
Answer: C
Topic: Concept 14.4
66) The frequency of heterozygosity for the sickle cell anemia allele is unusually high,
presumably because this reduces the frequency of malaria. Such a relationship is related to
which of the following?
A) Mendel's law of independent assortment
B) Mendel's law of segregation
C) Darwin's explanation of natural selection
D) Darwin's observations of competition
E) The malarial parasite changing the allele
Answer: C
Topic: Concept 14.4
67) Cystic fibrosis (CF) is a Mendelian disorder in the human population that is inherited as a
recessive. Two normal parents have two children with CF. The probability of their next child
being normal for this characteristic is which of the following?
A) 0
B) 1/2
C) 1/4
D) 3/4
E) 1/8
Answer: C
Topic: Concept 14.4
68) Phenylketonuria (PKU) is a recessive human disorder in which an individual cannot

appropriately metabolize a particular amino acid. This amino acid is not otherwise produced
by humans. Therefore the most efficient and effective treatment is which of the following?
A) Feed them the substrate that can be metabolized into this amino acid.
B) Transfuse the patients with blood from unaffected donors.
C) Regulate the diet of the affected persons to severely limit the uptake of the amino acid.
D) Feed the patients the missing enzymes in a regular cycle, i.e., twice per week.
Answer: C
Topic: Concept 14.4
18
69) Hutchinson‐Gilford progeria is an exceedingly rare human genetic disorder in which there is
very early senility, and death, usually of coronary artery disease, at an average age of
approximately 13. Patients, who look very old even as children, do not live to reproduce.
Which of the following represents the most likely assumption?
A) All cases must occur in relatives; therefore, there must be only one mutant allele.
B) Successive generations of a family will continue to have more and more cases over
time.
C) The disorder may be due to mutation in a single protein‐coding gene.
D) Each patient will have had at least one affected family member in a previous
generation.
E) The disease is autosomal dominant.
Answer: C
Topic: Concept 14.4
70) A pedigree analysis for a given disorder's occurrence in a family shows that, although both
parents of an affected child are normal, each of the parents has had affected relatives with
the same condition. The disorder is then which of the following?
A) Recessive
B) Dominant
C) Incompletely dominant
D) Maternally inherited
E) A new mutation
Answer: A
Topic: Concept 14.4
71) One of two major forms of a human condition called neurofibromatosis (NF 1) is inherited as
a dominant, although it may be either mildly to very severely expressed. If a young child is
the first in her family to be diagnosed, which of the following is the best explanation?
A) The mother carries the gene but does not express it at all.
B) One of the parents has very mild expression of the gene.
C) The condition skipped a generation in the family.
D) The child has a different allele of the gene than the parents.
Answer: B
Topic: Concept 14.4
19
Self‐Quiz Questions
Match each term on the left with a statement on the right.
1) Gene A) A variant for a character
2) Allele B) A cross between an individual

with an unknown genotype and a
homozygous recessive individual
3) Character
4) Trait C) Having two identical alleles for a

gene
5) Dominant allele
6) Recessive allele D) Having two different alleles for a

gene
7) Genotype E) An alternative version of a gene
8) Phenotype F) An organism's appearance or

observable traits
9) Homozygous
10) Heterozygous G) A heritable unit that determines a

character and can exist in
different forms.
11) Testcross
12) Monohybrid cross H) Determines phenotype in a

heterozygote
I) A heritable feature that varies

among individuals
J) The genetic makeup of an

individual
K) A cross between individuals

heterozygous for a single
character
L) Has no effect on phenotype in a

heterozygote
1) G 2) E 3) I 4) A 5) H 6) L
7) J 8) F 9) C 10) D 11) B 12) K
20
13) Two pea plants heterozygous for the characters of pod color and pod shape are crossed.
Draw a Punnett square to determine the phenotypic ratios of the offspring.
Answer:
14) In some plants, a true‐breeding, red‐flowered strain gives all pink flowers when crossed
with a white‐flowered strain: CRCR (red) × CWCW (white) CRCW (pink). If flower position
(axial or terminal) is inherited as it is in peas (see Table 14.1 in your textbook), what will be
the ratios of genotypes and phenotypes of the F1 generation resulting from the following
cross: axial‐red (true‐breeding) × terminal‐white? What will be the ratios in the F2
generation?
Answer: Parental cross is AACRCR × aaCWCW. Genotype of F1 is AaCRCW, phenotype is all
axial‐pink. Genotypes of F2 are 4 AaCRCW : 2 AaCRCR : 2 AACRCW : 2 aaCRCW : 2
AaCWCW : 1 AACRCR : 1 aaCRCR : 1 AACWCW : 1 aaCWCW. Phenotypes of F2 are 6
axial‐pink : 3 axial‐red : 3 axial‐white : 2 terminal‐pink : 1 terminal‐white : 1 terminal‐
red.
15) Flower position, stem length, and seed shape were three characters that Mendel studied.
Each is controlled by an independently assorting gene and has dominant and recessive
expression as follows: 
 
Character   Dominant   Recessive 
Flower position   Axial (A)   Terminal (a) 
Stem length   Tall (T)   Dwarf (t) 
Seed shape   Round (R)   Wrinkled (r) 
 
If a plant that is heterozygous for all three characters is allowed to self‐fertilize, what
proportion of the offspring would you expect to be as follows? (Note: Use the rules of
probability instead of a huge Punnett square.) 
A) Homozygous for the three dominant traits 
B) Homozygous for the three recessive traits 
C) Heterozygous for all three characters 
D) Homozygous for axial and tall, heterozygous for seed shape
Answer: A) 1⁄64, B) 1⁄64, C) 1⁄8, D) 1⁄32
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16) A black guinea pig crossed with an albino guinea pig produces 12 black offspring. When the
albino is crossed with a second black one, 7 blacks and 5 albinos are obtained. What is the
best explanation for this genetic situation? Write genotypes for the parents, gametes, and
offspring.
Answer: Albino (b) is a recessive trait; black (B) is dominant. First cross: parents BB × bb;
gametes B and b; offspring all Bb (black coat). Second cross: parents Bb × bb; gametes
1⁄2 B and 1⁄2 b (heterozygous parent) and b; offspring 1⁄2 Bb and 1⁄/2 bb.
17) In sesame plants, the one‐pod condition (P) is dominant to the three‐pod condition (p), and
normal leaf (L) is dominant to wrinkled leaf (l). Pod type and leaf type are inherited
independently. Determine the genotypes for the two parents for all possible matings
producing the following offspring: 
A) 318 one‐pod, normal leaf and 98 one‐pod, wrinkled leaf 
B) 323 three‐pod, normal leaf and 106 three‐pod, wrinkled leaf 
C) 401 one‐pod, normal leaf 
D) 150 one‐pod, normal leaf, 147 one‐pod, wrinkled leaf, 51 three‐pod, normal leaf, and 48
three‐pod, wrinkled leaf 
E) 223 one‐pod, normal leaf, 72 one‐pod, wrinkled leaf, 76 three‐pod, normal leaf, and 27
three‐pod, wrinkled leaf
Answer: A) PPLl × PPLl, PPLl × PpLl, or PPLl × ppLl. B) ppLl × ppLl. C) PPLL × any of the 9
possible genotypes or PPll × ppLL. D) PpLl × Ppll. E) PpLl × PpLl.
18) A man with type A blood marries a woman with type B blood. Their child has type O blood.
What are the genotypes of these individuals? What other genotypes, and in what
frequencies, would you expect in offspring from this marriage?
Answer: Man IAi; woman IBi; child ii. Other genotypes for children are 1⁄4 IAIB, 1⁄4 IAi, 1⁄4 IBi.
19) Phenylketonuria (PKU) is an inherited disease caused by a recessive allele. If a woman and
her husband, who are both carriers, have three children, what is the probability of each of
the following? 
A) All three children are of normal phenotype. 
B) One or more of the three children have the disease. 
C) All three children have the disease. 
D) At least one child is phenotypically normal. 
(Note: Remember that the probabilities of all possible outcomes always add up to 1.)
Answer: A) 3⁄4 × 3⁄4 × 3⁄4 = 27⁄64, B) 1 — 27⁄64 = 37⁄64, C) 1⁄4 × 1⁄4 × 1⁄4 = 1⁄64, D) 1 — 1⁄64=63⁄64
20) The genotype of F1 individuals in a tetrahybrid cross is AaBbCcDd. Assuming independent

assortment of these four genes, what are the probabilities that F2 offspring will have the
following genotypes? 
A) aabbccdd 
B) AaBbCcDd 
C) AABBCCDD 
D) AaBBccDd 
E) AaBBCCdd
Answer: A) 1⁄256, B) 1⁄16, C) 1⁄256, D) 1⁄64, E) 1/128
22
21) What is the probability that each of the following pairs of parents will produce the indicated
offspring? (Assume independent assortment of all gene pairs.) 
A) AABBCC × aabbcc AaBbCc 
B) AABbCc × AaBbCc AAbbCC 
C) AaBbCc × AaBbCc AaBbCc 
D) aaBbCC × AABbcc AaBbCc
Answer: A) 1, B) 1⁄32, C) 1⁄8, D) 1⁄2
22) Karen and Steve each have a sibling with sickle‐cell disease. Neither Karen nor Steve nor any
of their parents have the disease, and none of them have been tested to reveal sickle‐cell
trait. Based on this incomplete information, calculate the probability that if this couple has a
child, the child will have sickle‐cell disease.
Answer: 1/9
23) In 1981, a stray black cat with unusual rounded, curled‐back ears was adopted by a family in
California. Hundreds of descendants of the cat have since been born, and cat fanciers hope
to develop the curl cat into a show breed. Suppose you owned the first curl cat and wanted
to develop a true‐breeding variety. How would you determine whether the curl allele is
dominant or recessive? How would you obtain true‐breeding curl cats? How could you be
sure they are true‐breeding?
Answer: Matings of the original mutant cat with true‐breeding noncurl cats will produce both
curl and noncurl F1 offspring if the curl allele is dominant, but only noncurl offspring
if the curl allele is recessive. You would obtain some true‐breeding offspring
homozygous for the curl allele from matings between the F1 cats resulting from the
original curl × noncurl crosses whether the curl trait is dominant or recessive. You
know that cats are true‐breeding when curl × curl matings produce only curl
offspring. As it turns out, the allele that causes curled ears is dominant.
24) Imagine that a newly discovered, recessively inherited disease is expressed only in
individuals with type O blood, although the disease and blood group are independently
inherited. A normal man with type A blood and a normal woman with type B blood have
already had one child with the disease. The woman is now pregnant for a second time. What
is the probability that the second child will also have the disease? Assume that both parents
are heterozygous for the gene that causes the disease.
Answer: 1/16
25) In tigers, a recessive allele causes an absence of fur pigmentation (a white tiger) and a cross‐
eyed condition. If two phenotypically normal tigers that are heterozygous at this locus are
mated, what percentage of their offspring will be cross‐eyed? What percentage will be
white?
Answer: 25% will be cross‐eyed; all of the cross‐eyed offspring will also be white.
26) In corn plants, a dominant allele I inhibits kernel color, while the recessive allele i permits
color when homozygous. At a different locus, the dominant allele P causes purple kernel
color, while the homozygous recessive genotype pp causes red kernels. If plants
heterozygous at both loci are crossed, what will be the phenotypic ratio of the offspring?
Answer: The dominant allele I is epistatic to the P/p locus, and thus the genotypic ratio for the
F1 generation will be 9 I_P_ (colorless) : 3 I_pp (colorless) : 3 iiP_ (purple) : 1 iipp (red).
Overall, the phenotypic ratio is 12 colorless : 3 purple : 1 red.
23
27) The pedigree below traces the inheritance of alkaptonuria, a biochemical disorder. Affected
individuals, indicated here by the colored circles and squares, are unable to metabolize a
substance called alkapton, which colors the urine and stains body tissues. Does alkaptonuria
appear to be caused by a dominant allele or by a recessive allele? Fill in the genotypes of the
individuals whose genotypes can be deduced. What genotypes are possible for each of the
other individuals? 
Answer: Recessive. All affected individuals (Arlene, Tom, Wilma, and Carla) are homozygous
recessive aa. George is Aa, since some of his children with Arlene are affected. Sam,
Ann, Daniel, and Alan are each Aa, since they are all unaffected children with one
affected parent. Michael also is Aa, since he has an affected child (Carla) with his
heterozygous wife Ann. Sandra, Tina, and Christopher can each have the AA or Aa
genotype.
28) A man has six fingers on each hand and six toes on each foot. His wife and their daughter
have the normal number of digits. Extra digits is a dominant trait. What fraction of this
couple's children would be expected to have extra digits?
Answer: 1/2
29) Imagine that you are a genetic counselor, and a couple planning to start a family comes to
you for information. Charles was married once before, and he and his first wife had a child
with cystic fibrosis. The brother of his current wife, Elaine, died of cystic fibrosis. What is the
probability that Charles and Elaine will have a baby with cystic fibrosis? (Neither Charles
nor Elaine has cystic fibrosis.)
Answer: 1/6
30) In mice, black color (B) is dominant to white (b). At a different locus, a dominant allele (A)
produces a band of yellow just below the tip of each hair in mice with black fur. This gives a
frosted appearance known as agouti. Expression of the recessive allele (a) results in a solid
coat color. If mice that are heterozygous at both loci are crossed, what is the expected
phenotypic ratio of their offspring?
Answer: 9 B_A_ (agouti) : 3 B_aa (black) : 3 bbA_ (white) : 1 bbaa (white). Overall, 9 agouti : 3
black : 4 white.
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Biology, 8e (Campbell)

Chapter 14 Mendel and the Gene Idea

2) What is the difference between a monohybrid cross and a dihybrid cross?

3) A cross between homozygous purple‐flowered and homozygous white‐flowered pea plants

6) How many unique gametes could be produced through independent assortment by an

13) Which of the boxes correspond to plants with a heterozygous genotype?

14) Which of the plants will be true‐breeding?

16) Which of the following about the law of segregation is false?

Use the following information to answer the questions below.

26) These results indicate which of the following?

Use the following information to answer the questions below.

33) A 1:2:1 phenotypic ratio in the F2 generation of a monohybrid cross is a sign of

38) The relationship between genes S and N is an example of

Use the following information to answer the questions below.

45) Which of the following is a possible phenotype for the father?

52) Which of the following is an example of polygenic inheritance?

54) Which of the following provides an example of epistasis?

58) What is the genotype of individual II‐5?

60) What is the probability that individual III‐1 is Ww?

62) When a disease is said to have a multifactorial basis, it means that

68) Phenylketonuria (PKU) is a recessive human disorder in which an individual cannot

1) Gene A) A variant for a character

2) Allele B) A cross between an individual

4) Trait C) Having two identical alleles for a

6) Recessive allele D) Having two different alleles for a

7) Genotype E) An alternative version of a gene

8) Phenotype F) An organism's appearance or

10) Heterozygous G) A heritable unit that determines a

12) Monohybrid cross H) Determines phenotype in a

I) A heritable feature that varies

J) The genetic makeup of an

K) A cross between individuals

L) Has no effect on phenotype in a

20) The genotype of F1 individuals in a tetrahybrid cross is AaBbCcDd. Assuming independent

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