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  • Formation of Urine via Henle's Loop and Collecting Duct

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    Muhammad Abro
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    Urine is formed through a mechanism involving the loops of Henle and the collecting ducts. As fluid passes down the thin descending limb of Henle, it becomes more concentrated due to water reabsorption into the interstitium. As it ascends back up and through the collecting ducts, the fluid remains hypotonic due to the pumping of chloride ions out and the resorption of urea and water back into the blood with antidiuretic hormone, concentrating the urine.

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    Urine Formation

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    Urine is formed through a mechanism involving the loops of Henle and the collecting ducts. As fluid passes down the thin descending limb of Henle, it becomes more concentrated due to water reabsorption into the interstitium. As it ascends back up and through the collecting ducts, the fluid remains hypotonic due to the pumping of chloride ions out and the resorption of urea and water back into the blood with antidiuretic hormone, concentrating the urine.

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    18 Ansichten1 Seite

    Formation of Urine via Henle's Loop and Collecting Duct

    Hochgeladen von

    Muhammad Abro
    Urine is formed through a mechanism involving the loops of Henle and the collecting ducts. As fluid passes down the thin descending limb of Henle, it becomes more concentrated due to water reabsorption into the interstitium. As it ascends back up and through the collecting ducts, the fluid remains hypotonic due to the pumping of chloride ions out and the resorption of urea and water back into the blood with antidiuretic hormone, concentrating the urine.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Als DOC, PDF, TXT herunterladen oder online auf Scribd lesen
    Markieren Sie unangemessene Inhalte
    von 1

    Mechanism of Formation of Urine

    Descending thin limb of Henle is freely permeable to water and salt Due to increasing osmolarity of interstitium: lumenal volume decreases and osmolarity increases Ascending (thin and thick) limb of Henle and DCT are not permeable to water Lumenal volume does not change Urea enters lumen Cl- pumped into interstitium (Na+ follows) increases salt deep in medulla ultrafiltrate becomes hypotonic as it ascends Without ADH: collecting tubule/duct impermeable to water ADH (pars nervosa of pituitary) makes collecting tubule/duct freely permeable to water and urea increases water resorption, decreases urine volume, and increases urine tonicity increases urea content deep in medulla to maintain interstitial osmolarity gradient

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