Amiodarone

Ventricular arrhythmias life-threatening recurrent ventricular fibrillation

(VF) hemodynamically unstable ventricular tachycardia (VT)
/

: ( 1 )
- loading dose: 15 mg/kg/ 600-800 mg/1.73m2/ 1-2 414 5
mg/kg/ 200-400 mg/1.73m2/
(2.5 mg/kg/)
- maintenance dose 5 1
:
- loading dose: 800-1600 mg 1-2 1-3
600-800 mg 1-2 1
- maintenance dose : 400 mg ( supraventricular
tachycardias)
: ( 2
)
24 : 1000 mg
- 150 mg (100 ml.) ( 1 amp D5W 100 ml) 10
- 360 mg (200 ml.) ( 6 amp D5W 500 ml) drip 200 ml 6
.
- 540 mg (300 ml.) 18 . drip
(300 ml)
24 : 0.5 mg (720 /24 .) 1-6 mg/.
VF VT: 150 mg D5W 100 . 10
200 mg/tab., 150 mg/3 ml inj.
Pregnancy risk factor D

1.
2. Severe sinus node dysfunction, second and third degree A-V block
(Pacemaker)
3.
4. Ritronavir, Sparfloxacin, Nelfinavir, Amprenavir

( 400 mg./) 75% 520%

1. ( IV.)

2. , fatigue, maliase

3.
4.
5.
6. Pulmonary fibrosis, Pulmonary inflammation, Interstitial
pneumonitis
7. hyperthyroidism hypothyroidism
8. , cornea microdeposits, noninfectious epididymitis

(Sinus bradycardia), AV-block, hypotension Q-T interval

prolongation

1.
2. bradycardia Isoproterenol temporary pacemaker

1. Cyclosporine, Digoxin, Phenytoin, Oral anticoagulants, -blocker,
Methotrexate ( Amiodarone ) Theophylline
2. Cimetidine Amiodarone
3. , Sinus arrest Fentanyl

1.
2. 2
3.
4.
5.
6.