a TH/NPY TH/NPY

b TH NPY TH NPY

MPTP, MPTP,
+ Dark + Light
St 41 St 42

MPTP-treated VSC neurons

TH core NPY annulus Dark Light
20
20
∗∗ ∗∗
Neurons / VSC

10
10

∗∗ ∗∗ 0
0 TH NPY TH/NPY
[MPTP] 0 200 400 600 700 800 µM
Before WA
0 µM (control) c 30 min WA
Pigmented area (%)

80 700 µM 30 min WA in Sulpiride

60
800 µM
TH neurons

40 30 ∗∗
∗∗
∗∗ ∗∗
0 0
DLSC VSC PT MPTP- MPTP- Control
Dark Light

Figure 6