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System

System Excretary

Firstly described by Camilo Golgi (1898) in Nerve Cells of Barn Owl

Also called as Dictyosomes (Gr. Dictyes = net) / Golgi Complex / Lipochondria / Chondriome / Lipoidal Mitohondria

Has key position in functioning membrane system Provides connection between ER, perinuclear space, vesicles and plasmalemma

Formation involves synthesis of Cisternae

 Cisternae Tubules
N-acetylglucosamine galactose

Vescicles

N-acetylneuraminic acid

 Stacks of membrane-bound structures known as cisternae (1 m diameter) An individual stack is sometimes called a dictyosome A mammalian cell typically contains 40 to 100 stacks. Between four and eight cisternae are usually present in a stack Each cisterna comprises a flattened membrane disk, and carries Golgi enzymes to help or to modify cargo proteins that travel through them Golgi are involved in the sorting and post-translational modification of proteins

 It is a discrete granule or mass to a dispersed filamentous reticulum Shape and function varies with the metabolic state of the cell Consists of series of concentrically bent double membranes These are Cisternae / Saccules / Lamellar Units / Golgiosomes Cisternae interconnected and stacked together Each has 4 6 Cisternae having Cis (Entry) and Trans (Exit) face Originated by fusion of vesicles coming from ER

 Consist of Lipids : Protein (40 : 60) Low Level of nucleic acids Polysaccharides Enzymes of P.M., E.R., Mitochondria, Peroxysome (Thiamine Pyrophosphatase, Glycosyl transferase) Molecular Signals

 Inter and intracellular Transport (Protein Trafficking) Formation of cell plate The Golgi plays an important role in the synthesis of proteoglycans, which are molecules present in the extracellular matrix of animals Important part of endomembrane system Major site of carbohydrate synthesis. Protein Signaling Endosome formation Golgi has a putative role in apoptosis (GAAP-Golgi anti-apoptotic protein) Reverse Pinocytosis and exocytosis