\

\
, t 1l
V \
Name: h f,Y
PHR 142P- Quiz#8 - F2002
(points)

(2) 1 Ephedrineis a weakly basicdrug with Ku : 2.3 x IIa . Define intrinsic

partition coefficient for ephedrine.
, fFl
V =::3 [u: i, 6fc
f\!
[E] \o

(2) 2. Define apparentpartition coefficientfor a weak acid.

lrrn]"
K* :
t-.^-1
LA-J*
LHAJ,,n
r
'1

(2) 3. Write an equationwhich relatesKuooto pH for a weak acid. Be certain

(4) 4.Sketch a graphof Kuoovs pH for a weakacid. Indicatepredominantspecies

at variouspoints on the graphand indicatesignificant featuresjust as has
beendone in lecture.

Ko
u,.{
H.K K,7,