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  • Punch Biopsies of Melanoma: A Diagnostic Peril

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    Deba P Sarma
    13 Ansichten5 Seiten
    Dermatol Online J. 2005 Mar 1;11(1):7. Punch biopsies of melanoma: a diagnostic peril. Lorusso GD, Sarma DP, Sarwar SF. Source Department of Pathology, Veterans Affairs Medical Center and Louisiana State University Health Sciences Center, USA. glorus@lsuhsc.edu Abstract Excisional or incisional biopsies of melanoma are used to determine depth of tumor invasion and to plan subsequent treatment. Accurate determination of depth of melanoma invasion is critical for treatment decisions and prognosis. Incisional or punch biopsies can be perilous for histopathologic determination of invasion, and both over- and underestimation of invasion can occur when using incisional methods. Likewise, histologic factors can lead to over- and underestimation of invasion. Prognosis and treatment of melanoma are primarily determined by depth of tumor invasion. We discuss several scenarios that can lead to over- and underestimation of depth of invasion in incisional biopsy specimens. We therefore discourage incisional or punch biopsies of suspected melanoma and recommend that depth of invasion not be reported on these types of specimens. PMID: 15748548 [PubMed - indexed for MEDLINE]

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    Punch Biopsies of Melanoma: a Diagnostic Peril

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    Dermatol Online J. 2005 Mar 1;11(1):7. Punch biopsies of melanoma: a diagnostic peril. Lorusso GD, Sarma DP, Sarwar SF. Source Department of Pathology, Veterans Affairs Medical Center and Louisiana State University Health Sciences Center, USA. glorus@lsuhsc.edu Abstract Excisional or incisional biopsies of melanoma are used to determine depth of tumor invasion and to plan subsequent treatment. Accurate determination of depth of melanoma invasion is critical for treatment decisions and prognosis. Incisional or punch biopsies can be perilous for histopathologic determination of invasion, and both over- and underestimation of invasion can occur when using incisional methods. Likewise, histologic factors can lead to over- and underestimation of invasion. Prognosis and treatment of melanoma are primarily determined by depth of tumor invasion. We discuss several scenarios that can lead to over- and underestimation of depth of invasion in incisional biopsy specimens. We therefore discourage incisional or punch biopsies of suspected melanoma and recommend that depth of invasion not be reported on these types of specimens. PMID: 15748548 [PubMed - indexed for MEDLINE]

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    13 Ansichten5 Seiten

    Punch Biopsies of Melanoma: A Diagnostic Peril

    Hochgeladen von

    Deba P Sarma
    Dermatol Online J. 2005 Mar 1;11(1):7. Punch biopsies of melanoma: a diagnostic peril. Lorusso GD, Sarma DP, Sarwar SF. Source Department of Pathology, Veterans Affairs Medical Center and Louisiana State University Health Sciences Center, USA. glorus@lsuhsc.edu Abstract Excisional or incisional biopsies of melanoma are used to determine depth of tumor invasion and to plan subsequent treatment. Accurate determination of depth of melanoma invasion is critical for treatment decisions and prognosis. Incisional or punch biopsies can be perilous for histopathologic determination of invasion, and both over- and underestimation of invasion can occur when using incisional methods. Likewise, histologic factors can lead to over- and underestimation of invasion. Prognosis and treatment of melanoma are primarily determined by depth of tumor invasion. We discuss several scenarios that can lead to over- and underestimation of depth of invasion in incisional biopsy specimens. We therefore discourage incisional or punch biopsies of suspected melanoma and recommend that depth of invasion not be reported on these types of specimens. PMID: 15748548 [PubMed - indexed for MEDLINE]

    Copyright:

    Attribution Non-Commercial (BY-NC)
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    Lorusso GD, Sarma DP, Sarwar SF. (2005): Punch biopsies of melanoma: a diagnostic peril.

    Dermatol Online J 11(1) PMID: 15748548 [PubMed - indexed for MEDLINE]

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